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Scientist/Senior Scientist, PK/PD Assays

NewLimit - South San Francisco

Posted Apr 17, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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Childcare support
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Learning budget
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Verification
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Salary
$130K-$160K Verified - from the job posting source checked Jun 20, 2026
401(k) match
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Market context

U.S. role benchmark (BLS OEWS)
$81,444 U.S. median for this role
Projected growth (BLS Employment Projections)
+6.9% - Faster than average

78% above the BLS role benchmark for healthcare aggregate.

Matched to SOC 29-1141 - Healthcare aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

Shift type
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Weekend work
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Application

Cover letter
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Assessment
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Deadline
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Where they hire

State eligibility is not yet verified.

About this role

Scientist/Senior Scientist, PK/PD Assays South San Francisco About NewLimit NewLimit is seeking a Scientist or Senior Scientist with deep expertise in molecular biology, pharmacokinetics and translational biomarker assay development. In this role, you will lead the design, development, and qualification of pharmacokinetic (PK) and pharmacodynamic (PD) assays that characterize the biodistribution and biological activity of our mRNA-LNP medicines in preclinical and IND enabling studies. You will serve as a technical leader within our bioanalytical function, shaping biomarker assay strategy and partnering cross-functionally to advance our therapeutic programs toward IND-enabling milestones. What you'll do - Own the end-to-end design, development, and qualification of PK and PD biomarker assays across various platforms to support preclinical and IND-enabling studies - Discover and validate pharmacodynamic biomarkers to support the clinical development of drugs across multiple programs - Drive data analysis, interpretation, and reporting for bioanalytical studies to support program decision-making with audit-ready data packages - Contribute to sample processing workflows including tissue harvesting, primary cell culture, and complex matrix handling - Mentor research associates, establish SOPs, and build institutional knowledge within the bioanalytical function Requirements - PhD in molecular biology, biochemistry, cell biology, or a related field or equivalent industry experience (5+ years) - 3+ years of hands-on experience in various quantitative bioanalytical assay platforms (e.g., RT-qPCR, ddPCR, ELISA, MSD, Olink, SOMAscan, NGS-based methods) in complex biological matrices (serum, plasma, tissue homogenates) - Strong working knowledge of bioanalytical method qualification/validation principles for PK/PD biomarker measurements, including familiarity with ICH M10 guidelines and fit-for-purpose frameworks

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