Scientist/Senior Scientist, PK/PD Assays
NewLimit - South San Francisco
Posted Apr 17, 2026
Benefits
- Parental leave
- Not verified
- Non-birth-parent leave
- Not verified
- Family-building benefits
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- Fertility benefits: Not verified
- Adoption assistance: Not verified
- Surrogacy assistance: Not verified
- Mental health support
- Not verified
- Relocation assistance
- Not verified
- Childcare support
- Not verified
- Learning budget
- Not verified
- Verification
- Not verified
- Salary
- $130K-$160K Verified - from the job posting source checked Jun 20, 2026
- 401(k) match
- Reported not verified - source not recorded; source URL not recorded; timestamp not recorded
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Market context
- U.S. role benchmark (BLS OEWS)
- $81,444 U.S. median for this role
- Projected growth (BLS Employment Projections)
- +6.9% - Faster than average
78% above the BLS role benchmark for healthcare aggregate.
Matched to SOC 29-1141 - Healthcare aggregate by role bucket.
Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.
Schedule
- Shift type
- Not verified
- Weekend work
- Not verified
Application
- Cover letter
- Not verified
- Assessment
- Not verified
- Deadline
- Not stated
Where they hire
State eligibility is not yet verified.
About this role
Scientist/Senior Scientist, PK/PD Assays South San Francisco About NewLimit NewLimit is seeking a Scientist or Senior Scientist with deep expertise in molecular biology, pharmacokinetics and translational biomarker assay development. In this role, you will lead the design, development, and qualification of pharmacokinetic (PK) and pharmacodynamic (PD) assays that characterize the biodistribution and biological activity of our mRNA-LNP medicines in preclinical and IND enabling studies. You will serve as a technical leader within our bioanalytical function, shaping biomarker assay strategy and partnering cross-functionally to advance our therapeutic programs toward IND-enabling milestones. What you'll do - Own the end-to-end design, development, and qualification of PK and PD biomarker assays across various platforms to support preclinical and IND-enabling studies - Discover and validate pharmacodynamic biomarkers to support the clinical development of drugs across multiple programs - Drive data analysis, interpretation, and reporting for bioanalytical studies to support program decision-making with audit-ready data packages - Contribute to sample processing workflows including tissue harvesting, primary cell culture, and complex matrix handling - Mentor research associates, establish SOPs, and build institutional knowledge within the bioanalytical function Requirements - PhD in molecular biology, biochemistry, cell biology, or a related field or equivalent industry experience (5+ years) - 3+ years of hands-on experience in various quantitative bioanalytical assay platforms (e.g., RT-qPCR, ddPCR, ELISA, MSD, Olink, SOMAscan, NGS-based methods) in complex biological matrices (serum, plasma, tissue homogenates) - Strong working knowledge of bioanalytical method qualification/validation principles for PK/PD biomarker measurements, including familiarity with ICH M10 guidelines and fit-for-purpose frameworks
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