Sr Associate Scientist I or II, Medicinal Chemistry

Benefits

Parental leave

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Non-birth-parent leave

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Family-building benefits

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Mental health support

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Relocation assistance

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Childcare support

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401(k) match

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Market context

Median wage (BLS OEWS)

$111,944 national median

Projected growth (BLS Employment Projections)

+13.7% - Much faster than average

Matched to SOC 15-1252 - Data and ML aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

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Weekend work

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Application

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Assessment

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Deadline

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Where they hire

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About this role

Sr Associate Scientist I or II, Medicinal Chemistry San Diego HQ, San Diego, California, United States JOB SUMMARY We are seeking a highly skilled and motivated Senior Associate Scientist to join the Chemistry team at Iambic Therapeutics headquarters in San Diego. This position offers the opportunity to work within a dynamic, cross-functional environment, collaborating closely with medicinal chemists, biologists, DMPK scientists, computational chemists, machine learning researchers, and software engineers throughout all stages of discovery, from hit identification and lead optimization through candidate selection. This is a laboratory-based Associate Scientist position that requires strong technical expertise in organic synthesis, catalysis, and medicinal chemistry, as well as hands-on experience in the drug discovery process and a demonstrated “drug hunter” mindset. KEY RESPONSIBILITIES - Design, synthesize, purify, and characterize chemical compounds (10 mg-5 g scale) using modern analytical techniques such as LCMS, HPLC, and NMR, employing both individual and automated parallel synthesis approaches. - Identify and optimize reaction conditions using screening kits and other streamlined methodologies. - Collaborate with the high-throughput experimentation team to ensure the successful execution of parallel chemistry experiments. - Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning. - Partner with computational chemists to leverage machine learning insights for efficient execution of the design-make-test cycle and platform development. - Present results to project teams and senior leadership, clearly communicating data, implications, and recommendations. QUALIFICATIONS - BS in Chemistry with 5+ years experience (pharma/biotech) or MS in Chemistry with 3+ years experience (pharma/biotech).

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