Director, Medicinal Chemistry

Benefits

Parental leave

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Non-birth-parent leave

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Family-building benefits

• Fertility benefits: Not verified
• Adoption assistance: Not verified
• Surrogacy assistance: Not verified

Mental health support

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Relocation assistance

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Childcare support

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Learning budget

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Verification

Not verified checked Jun 13, 2026

Salary

$223K-$234K From the posting source checked Jun 20, 2026

401(k) match

Reported from DOL Form 5500 industry filing (not employer-specific)

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Role

Seniority

Director Plus From the posting source checked Jun 20, 2026

Schedule

Shift type

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Weekend work

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Company

Equity

Offered Verified - SEC 10-K source checked Jun 20, 2026

Application

Cover letter

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Assessment

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Deadline

Not stated

Where they hire

State eligibility is not yet verified.

About this role

Director, Medicinal Chemistry Waltham, MA, United States Alkermes has an exciting opportunity for a talented scientist to join our Research Organization as a Director to help lead medicinal chemistry efforts from target ideation through to candidate nomination for neurological disease indications. The desired candidate will be a recognized expert in successfully initiating and managing the medicinal chemistry activities inside a given portfolio and will play a key strategic role in shaping discovery direction and compound design strategy. The candidate will have a proven track record of utilizing structure-based drug design (SBDD) to rationally design compounds that have progressed to candidate delivery. Additionally, the candidate must have direct experience of working with both internal and external partners (e.g., CROs) to facilitate medicinal chemistry activities. Exceptional cross-functional communication skills as well as experience in leading drug discovery teams are necessary attributes. Lead medicinal chemistry projects to ensure project progression and candidate drug delivery using state-of-the-art design principles and strategies. Work closely with computational chemistry to implement relevant predictive models to aid in the design of new compounds. Foster a close collaboration with synthetic chemistry to enhance design through synthesis. Utilize state of the art design tools to provide systematic data analysis to assist in hypothesis driven compound design. Collaborate with cross-functional colleagues to focus project priorities, objectives, and outcomes. Advise and assist project leaders in the development of strategic, scientific, and technical strategies for the progression of molecules by evaluating the needs of projects across the portfolio for all proposed compounds. Provide

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