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Director/Senior Director, Medicinal Chemistry

Iambic Therapeutics - San Diego HQ, San Diego, California, United States

Posted Apr 15, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
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  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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Childcare support
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Learning budget
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Verification
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Salary
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401(k) match
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Market context

U.S. role benchmark (BLS OEWS)
$116,543 U.S. median for this role
Projected growth (BLS Employment Projections)
+9.8% - Much faster than average

Matched to SOC 15-1252 - Software Engineering aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function
Engineering From the posting source checked Jun 20, 2026
Seniority
Director Plus From the posting source checked Jun 20, 2026

Schedule

Shift type
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Weekend work
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Company

Company stage
Growth-stage From the posting source checked Jun 20, 2026

Application

Cover letter
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Assessment
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Deadline
Not stated

Where they hire

State eligibility is not yet verified.

About this role

Director/Senior Director, Medicinal Chemistry San Diego HQ, San Diego, California, United States JOB SUMMARY We seek an accomplished and creative medicinal chemistry leader with a proven track record of success in advancing drug discovery programs, setting scientific strategy, and leading cross-functional teams to deliver impact. Candidates should be motivated to work in an intensely collaborative, multidisciplinary, team-based setting. The role will entail leading drug discovery projects, coordinating a medicinal chemistry team with internal and external experimental capabilities, as well as proactively interfacing with diverse teams working on automated experimentation, ML-driven molecular generation, property predictions, and bioassay data generation. This position will be on-site at our San Diego Headquarters. KEY RESPONSIBILITIES - Lead a group of project scientists and drive molecular discovery efforts to deliver development and clinical candidates - Devise strategies to execute hit ID, identify lead molecules and optimize them for potency, selectivity, and ADME properties using multivariant SAR analysis and hypothesis driven design principles. - Act as a liaison between Iambic, CROs, and other external collaborators, including partnered research projects - Influence the prospective use of computational methods and leverage automated synthesis and high-throughput experimentation capabilities - Work closely with AI/ML teams to develop and implement relevant predictive models to aid in the design of new molecules - Contribute to platform development by collaborating with AI/ML and chemistry automation teams to enhance processes and accelerate the design-make-test (DMT) cycle. - Communicate project updates clearly and effectively to the broader team and key stakeholders - Work as a senior

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