Director/Senior Director, Medicinal Chemistry
Iambic Therapeutics - San Diego HQ, San Diego, California, United States
Posted Apr 15, 2026
Benefits
- Parental leave
- Not verified
- Non-birth-parent leave
- Not verified
- Family-building benefits
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- Fertility benefits: Not verified
- Adoption assistance: Not verified
- Surrogacy assistance: Not verified
- Mental health support
- Not verified
- Relocation assistance
- Not verified
- Childcare support
- Not verified
- Learning budget
- Not verified
- Verification
- Not verified
- Salary
- Not verified
- 401(k) match
- Reported not verified - source not recorded; source URL not recorded; timestamp not recorded
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Market context
- U.S. role benchmark (BLS OEWS)
- $116,543 U.S. median for this role
- Projected growth (BLS Employment Projections)
- +9.8% - Much faster than average
Matched to SOC 15-1252 - Software Engineering aggregate by role bucket.
Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.
Role
Schedule
- Shift type
- Not verified
- Weekend work
- Not verified
Company
- Company stage
- Growth-stage From the posting source checked Jun 20, 2026
Application
- Cover letter
- Not verified
- Assessment
- Not verified
- Deadline
- Not stated
Where they hire
State eligibility is not yet verified.
About this role
Director/Senior Director, Medicinal Chemistry San Diego HQ, San Diego, California, United States JOB SUMMARY We seek an accomplished and creative medicinal chemistry leader with a proven track record of success in advancing drug discovery programs, setting scientific strategy, and leading cross-functional teams to deliver impact. Candidates should be motivated to work in an intensely collaborative, multidisciplinary, team-based setting. The role will entail leading drug discovery projects, coordinating a medicinal chemistry team with internal and external experimental capabilities, as well as proactively interfacing with diverse teams working on automated experimentation, ML-driven molecular generation, property predictions, and bioassay data generation. This position will be on-site at our San Diego Headquarters. KEY RESPONSIBILITIES - Lead a group of project scientists and drive molecular discovery efforts to deliver development and clinical candidates - Devise strategies to execute hit ID, identify lead molecules and optimize them for potency, selectivity, and ADME properties using multivariant SAR analysis and hypothesis driven design principles. - Act as a liaison between Iambic, CROs, and other external collaborators, including partnered research projects - Influence the prospective use of computational methods and leverage automated synthesis and high-throughput experimentation capabilities - Work closely with AI/ML teams to develop and implement relevant predictive models to aid in the design of new molecules - Contribute to platform development by collaborating with AI/ML and chemistry automation teams to enhance processes and accelerate the design-make-test (DMT) cycle. - Communicate project updates clearly and effectively to the broader team and key stakeholders - Work as a senior
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