Senior Scientist, mRNA engineering

Benefits

Parental leave

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Non-birth-parent leave

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Family-building benefits

• Fertility benefits: Not verified
• Adoption assistance: Not verified
• Surrogacy assistance: Not verified

Mental health support

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Relocation assistance

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Childcare support

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Learning budget

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Verification

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Salary

$160K-$185K From the posting source checked Jun 20, 2026

401(k) match

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Market context

U.S. role benchmark (BLS OEWS)

$116,543 U.S. median for this role

Projected growth (BLS Employment Projections)

+9.8% - Much faster than average

48% above the BLS role benchmark for software engineering aggregate.

Matched to SOC 15-1252 - Software Engineering aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function

Engineering From the posting source checked Jun 20, 2026

Seniority

Senior From the posting source checked Jun 20, 2026

Schedule

Shift type

Not verified

Weekend work

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Application

Cover letter

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Assessment

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Deadline

Not stated

Where they hire

State eligibility is not yet verified.

About this role

Senior Scientist, mRNA engineering South San Francisco About NewLimit NewLimit is a biotechnology company working to radically extend human healthspan. We're developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale. Position NewLimit is seeking a Senior Scientist to drive our mRNA production and engineering efforts. This is a hands-on, lab based role focused on the synthesis, purification, and characterization of mRNA at large scales and high purities. You will serve as the technical lead for our production workflow, bridging the gap between molecular design and high quality material generation for in vivo and in vitro studies. What you'll do As a member of our team, you will: - Execute and scale end-to-end mRNA production, including template preparation, in vitro transcription (IVT), and purification (TFF, chromatography). - Implement rigorous quality control assays, including direct RNA sequencing, fragment analysis, dsRNA quantitation, and residual contaminant analysis. - Author and maintain detailed SOPs and batch records, ensuring all production runs meet GLP standards. - Independently design and execute experiments to improve mRNA sequence potency, specificity, and manufacturing performance. - Train, manage, and mentor other team members on mRNA optimization and production workflows. Requirements - PhD in molecular biology, biochemistry, cell biology, or a related field or equivalent industry experience (5+ years). - Deep hands-on experience

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