Senior/Research Associate, Functional Genomics

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About this role

Senior/Research Associate, Functional Genomics South San Francisco, CA About NewLimit NewLimit is a biotechnology company working to radically extend human healthspan. We're developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale. Position NewLimit is seeking a Senior/Research Associate with experience in molecular biology to join our Epigenetic Editing group. Pooled screening technologies are at the heart of our discovery engine, allowing us to rapidly search for epigenetic reprogramming therapies that restore cell function and reduce the burden of disease. As a member of our team, you will: - Collaborate with our Single Cell Technology team to implement large-scale, single cell perturbation experiments with custom chemistries - Build recombinant DNA vectors by synthesis and cloning to enable large-scale single cell perturbation experiments - Prepare, titer, and apply viral vectors (lentiviral, AAV) to transduce mammalian cell lines and primary cells - Contribute to scaling and improving pooled single cell perturbation screens Requirements - Bachelor's degree in cell biology, molecular biology, or a related natural science or industry experience - 2+ years of work experience in a cell or molecular biology laboratory (academic or industry) - Experience with molecular cloning, nucleic acid analysis (RT-qPCR, gel electrophoresis), and related molecular biology methods - Experience with mammalian cell culture Nice to have - Experience with next-generation

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