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Sr. Bioinformatics Scientist – Novel Cell Free DNA Applications

Personalis INC - Fremont, CA

Posted Feb 4, 2026

Benefits

Parental leave
Not verified
Non-birth-parent leave
Not verified
Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
Not verified
Childcare support
Not verified
Learning budget
Offered Verified - from the job posting source checked Jun 20, 2026
Verification
Not verified checked Jun 13, 2026
Salary
$155K-$190K Verified - from the job posting source checked Jun 20, 2026
401(k) match
Reported from DOL Form 5500 industry filing (not employer-specific)

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Market context

U.S. role benchmark (BLS OEWS)
$111,944 U.S. median for this role
Projected growth (BLS Employment Projections)
+13.7% - Much faster than average

54% above the BLS role benchmark for data and ml aggregate.

Matched to SOC 15-1252 - Data and ML aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

Shift type
Not verified
Weekend work
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Company

Company stage
Public-company Verified - from the job posting source checked Jun 20, 2026
Equity
Offered Verified - from the job posting source checked Jun 20, 2026

Application

Cover letter
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Assessment
Not verified
Deadline
Not stated

Where they hire

State eligibility is not yet verified.

About this role

Sr. Bioinformatics Scientist – Novel Cell Free DNA Applications Fremont, CA Personalis, Inc. is a leader in advanced genomics for precision oncology. NeXT Personal is an ultra-sensitive, tumor-informed, WGS-based liquid biopsy assay designed to detect minimal residual disease (MRD) and cancer recurrence. It leverages whole-genome sequencing of a patient's tumor and matched normal samples to create personalized panel of up to 1,800 somatic variants, enabling the detection of circulating tumor DNA (ctDNA) at very low levels (down to ~1-3 PPM) in blood samples. To enable cancer and population sequencing, Personalis' Clinical Laboratory was built with a focus on clinical accuracy, quality, big data, scale, and efficiency. Days Onsite: Monday & Tuesday Summary: The Senior Bioinformatics Scientist will work with a world-class, dynamic team of bioinformatics scientists, software engineers, and laboratory scientists, developing, testing, and applying cutting-edge cell-free and solid tumor cancer genomics products. Further, the Senior Bioinformatics Scientist will work closely with our clinical evidence generation teams, applying our cell-free technology solutions to large cancer patient cohorts and profiling patient response to therapy with our cfDNA platforms. This position will directly contribute to a new generation of genomics-based precision-medicine products for profiling MRD, ctDNA dynamics, and patient response to treatment. Our products are used by pharma, biotech, hospitals, and clinicians for managing patient treatment and therapeutic selection. Responsibilities: Design and develop novel cell-free technologies and products Collaborate closely with laboratory scientists to design experiments to develop and evaluate novel applications for cell-free DNA assays Draw on deep experience with genomics

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