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Head of Manufacturing

NewLimit - South San Francisco

Posted May 5, 2026

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About this role

Head of Manufacturing South San Francisco Company info NewLimit is a biotechnology company working to radically extend human healthspan. We're developing medicines to treat aging and age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and artificial intelligence systems to unravel the biology of aging and disease using experiments of unprecedented scale. Description NewLimit is recruiting a Head of Manufacturing to lead drug substance and product chemistry, manufacturing, and controls (CMC). We are creating a new class of epigenetic reprogramming medicines for aging that build upon LNP and mRNA technology. Our initial assets are progressing through the complex manufacturing cascade that these modalities entail. In this role, you will orchestrate manufacturing for some of the first reprogramming medicines to enter human trials. You will serve as the company's resident expert in manufacturing & controls, and manage a team of talented scientists & engineers to achieve your goals. As part of the role you will: - Lead manufacturing campaigns for epigenetic reprogramming medicines spanning DNA, mRNA, and lipid nanoparticle manufacturing - Own manufacturing timelines and deliverables for the world's first reprogramming medicines - Orchestrate contract manufacturing organizations, debug logistical issues, and keep timelines on track - Manage and recruit talented scientists and engineers in drug substance and drug product teams - Get in the lab and help teach, troubleshoot, and unblock projects Requirements - Ph.D. in a natural science or engineering discipline (biology, chemistry;

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