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Senior Scientist, Chip and Surface Chemistry

Nautilus Biotechnology - San Carlos, 1561 Industrial Road, San Carlos, California, USA

Posted Feb 25, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
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  • Adoption assistance: Not verified
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Mental health support
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Relocation assistance
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Childcare support
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Market context

U.S. role benchmark (BLS OEWS)
$111,944 U.S. median for this role
Projected growth (BLS Employment Projections)
+13.7% - Much faster than average

Matched to SOC 15-1252 - Data and ML aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function
Data From the posting source
Seniority
Senior From the posting source

Schedule

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Weekend work
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Company

Equity
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Application

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Assessment
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Deadline
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Where they hire

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About this role

Senior Scientist, Chip and Surface Chemistry San Carlos, 1561 Industrial Road, San Carlos, California, USA At Nautilus, our mission is to transform global health by harnessing the potential of the proteome to accelerate drug discovery and advance the era of precision and personalized medicine. We are pioneering the development of a single-molecule protein analysis platform distinguished by its exceptional sensitivity, scalability, and ease of use-aimed at democratizing access to the proteome, one of biology's most dynamic and valuable sources of insight. Achieving this vision requires rigorous scientific innovation paired with an entrepreneurial spirit, and we are assembling a world-class team of talented builders, innovators, and visionaries from diverse fields. We are seeking a highly qualified Senior Scientist to enhance the functionality and reliability of our platform's flow cell and surface chemistry components. The ideal candidate will possess a strong background in surface chemistry and process development, with the ability to apply their expertise across domains such as assay development, metrology, data analysis, and system integration. Responsibilities • Collaborate with lead scientists and engineers to develop and validate processes related to nanofabrication, surface chemistry, and flow cell assembly. • Design and implement analytical and functional methodologies to characterize and assess the effectiveness of chip patterning, surface chemistry, and flow cell assembly processes. • Test and implement assay, flow cell, and surface chemistry improvements on Nautilus' proteomics platform. • Apply statistical process control methods to establish and maintain control and specification limits. • Experience with DNA origami design, fabrication, and integration in

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