Director, Discovery Chemistry

Benefits

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Salary

$184K-$246K not verified - source not recorded; timestamp not recorded

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About this role

Director, Discovery Chemistry Cambridge, MA USA Your Impact at LILA The Director, Discovery Chemistry will lead the design, synthesis, and optimization of small molecules across Lila's discovery platform, with a primary focus on organic synthesis, molecular design, and scalable chemistry execution . This leader will build and scale a world-class molecular chemistry program that translates AI-generated molecular hypotheses into high-quality, synthetically tractable, and functionally validated chemical matter. Working closely with Lila's AI, automation, computational, biology, and platform teams, this role will establish the chemistry infrastructure required to rapidly progress novel molecules from concept to validated candidates across a broad range of discovery efforts. The Director will drive synthetic strategy, route design, analog generation, molecular property optimization, and chemistry-enabled innovation, while enabling seamless integration with robotic synthesis and platform-based experimentation. This leader will play a central role in shaping Lila's molecular discovery engine by combining deep expertise in synthetic organic chemistry, molecular design, and data-enabled experimentation to accelerate the discovery of high-value molecules for therapeutic and broader platform applications. What You'll Be Building - Drive discovery chemistry strategy across discovery programs, with strong emphasis on small molecule design, synthetic innovation, analog generation, and optimization of chemical matter. - Lead the design and execution of synthetic routes for novel small molecules, emphasizing speed, robustness, scalability, and compatibility with automated synthesis platforms. - Develop and implement efficient workflows for molecular design, compound prioritization, analog generation, and iterative design-make-test cycles in collaboration with AI and computational teams. - Partner closely with automation and platform

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