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Senior Scientist, Oligonucleotide Therapeutics

Insitro - South San Francisco, CA

Posted May 7, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
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  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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401(k) match
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Market context

Median wage (BLS OEWS)
$111,944 national median
Projected growth (BLS Employment Projections)
+13.7% - Much faster than average

Matched to SOC 15-1252 - Data and ML aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

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Weekend work
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Application

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Deadline
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Where they hire

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About this role

Senior Scientist, Oligonucleotide Therapeutics South San Francisco, CA The Opportunity At the heart of insitro's strategy is to generate multi-modal phenotypic cellular data in our automated laboratories for our cell machine learning platform and utilize high content human clinical, imaging and genetic data in our clinical machine learning platform to unlock and de-risk novel therapeutic targets for drug discovery. Our drug discovery efforts span from small molecules to oligonucleotides. We are seeking a highly motivated scientist to support our growing efforts in the oligonucleotide drug discovery space. This role will report to the head of our oligonucleotide drug discovery. In this role the candidate will get an opportunity to work across targets and therapeutic areas and will be supporting oligonucleotide drug discovery and tech dev encompassing several modalities such as siRNAs, ASOs and mRNA. The ideal candidate will be working in a highly collaborative environment with our therapeutic area scientists, AI/ML scientists, and chemists, to bring transformative medicines to patients faster. You will be joining a vibrant biotech startup that has long-term stability, with significant funding, and in a high-growth phase, and you will have many opportunities to make a significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro's culture, strategic direction, and outcomes. Join us, and help make a difference to patients! This is an onsite role based in insitro's South San Francisco headquarters, coming onsite 3-4 days a week. Responsibilities - Design and optimize siRNA, antisense

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