Senior Director, Project & Portfolio Management
Insitro - South San Francisco, CA
Posted Jan 9, 2026
Benefits
- Parental leave
- Not verified
- Non-birth-parent leave
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- Family-building benefits
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- Fertility benefits: Not verified
- Adoption assistance: Not verified
- Surrogacy assistance: Not verified
- Mental health support
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- Relocation assistance
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- Childcare support
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- Learning budget
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- Verification
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- Salary
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- 401(k) match
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Market context
- U.S. role benchmark (BLS OEWS)
- $106,409 U.S. median for this role
- Projected growth (BLS Employment Projections)
- +7.7% - Faster than average
Matched to SOC 13-2011 - Finance aggregate by role bucket.
Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.
Schedule
- Shift type
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- Weekend work
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Application
- Cover letter
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- Assessment
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- Deadline
- Not stated
Where they hire
State eligibility is not yet verified.
About this role
Senior Director, Project & Portfolio Management South San Francisco, CA The Opportunity The unprecedented convergence of multi-modal data, advanced disease modeling, and computational power is revolutionizing drug discovery. insitro is harnessing this moment to redefine how medicines are developed for complex diseases. Our AI/ML-enabled platforms integrate and scale data to rapidly discover novel biological insights to redefine complex diseases and identify new targets and drugs. To enable this vision we are seeking a Senior Director of Project & Portfolio Management (PPM) who will build an AI-forward PPM organization that will partner with Therapeutic Area, Operations, Clinical and Business Development teams to discover and advance a high-value portfolio of exciting drug candidates into the clinic for neurological, ophthalmological and metabolic indications. Reporting into the CSO, you and your staff will partner with project team leaders in developing rightsized project strategies and create successful team environments to foster high performance and rapid advancement. You will develop and execute high quality integrated project plans with clear timelines spanning research, discovery, clinical development, software engineering, and data science/machine learning. As the leader of PPM you will partner with Compute, Operations and Finance colleagues in establishing agentic AI project management, decision and resource allocation tools and methodologies across our portfolio to support critical initiatives. This role will be hybrid, coming onsite to our South San Francisco headquarters with three days per week in the office. About You - BS degree required in a life science field, MS or PhD preferred - Minimum of 15 years
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