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Senior Clinical Trial Manager, Clinical Operations

Iambic Therapeutics - Remote - US, San Diego, California, United States

Posted Jun 11, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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Childcare support
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Learning budget
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Verification
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Salary
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401(k) match
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Market context

U.S. role benchmark (BLS OEWS)
$81,444 U.S. median for this role
Projected growth (BLS Employment Projections)
+6.9% - Faster than average

Matched to SOC 29-1141 - Healthcare aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function
Healthcare From the posting source checked Jun 20, 2026
Seniority
Senior From the posting source checked Jun 20, 2026
Work mode
Remote From the posting source checked Jun 20, 2026
In-office days
0 days From the posting source checked Jun 20, 2026

Schedule

Shift type
Not verified
Weekend work
Not verified

Company

Company stage
Growth-stage From the posting source checked Jun 20, 2026

Application

Cover letter
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Assessment
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Deadline
Not stated

Where they hire

State eligibility is not yet verified.

About this role

Senior Clinical Trial Manager, Clinical Operations Remote - US, San Diego, California, United States JOB SUMMARY The Senior Clinical Trial Manager, Clinical Operations, serves as the operational lead for assigned early-phase oncology studies, providing end-to-end trial leadership from start-up through close-out. In close partnership with Clinical Development, Regulatory, Biometrics, and external CROs, this role drives high-quality, inspection-ready trial execution within a collaborative, growth-stage biotech environment. The Senior CTM is accountable for vendor oversight, risk management, timeline and budget performance, and cross-functional alignment to ensure studies are delivered efficiently and in compliance with global regulatory requirements, ICH-GCP, and company SOPs. This position reports to the Director of Clinical Operations and can be remote or onsite in San Diego. KEY RESPONSIBILITIES - Provide end-to-end operational leadership for complex clinical trials from start-up through close-out, ensuring delivery on time, within budget, and in compliance with global regulations and company SOPs - Lead cross-functional study teams and drive alignment across Clinical Development, Regulatory, Biometrics, and external partners - Develop and execute enrollment, site management, and monitoring strategies to ensure high-quality trial conduct and performance - Oversee CRO and vendor performance, including KPI management, monitoring quality oversight, document review and approval, and vendor selection support - Partner with Data Management and Medical to conduct ongoing data review and ensure timely query resolution - Develop and manage key study documents and operational tools, including protocols, informed consent forms, project plans, budgets, and study materials. - Lead study-related training for investigators, site personnel, and internal teams. -

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