Principal Scientist / Senior Scientist, Analytical Chemistry (Biopolymers)

Benefits

Parental leave

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Non-birth-parent leave

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Family-building benefits

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Mental health support

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Market context

U.S. role benchmark (BLS OEWS)

$111,944 U.S. median for this role

Projected growth (BLS Employment Projections)

+13.7% - Much faster than average

Matched to SOC 15-1252 - Data and ML aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function

Data From the posting source

Seniority

Staff Plus From the posting source

Work mode

Onsite From the posting source

In-office days

5 days From the posting source

Schedule

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Weekend work

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Company

Equity

Offered From the posting source

Application

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Deadline

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About this role

Principal Scientist / Senior Scientist, Analytical Chemistry (Biopolymers) South San Francisco, CA Principal Scientist / Senior Scientist, Analytical Chemistry (Biopolymers) Location: Brisbane, CA (Onsite) About BreezeBio BreezeBio is an early-stage biotech company building a next-generation delivery platform for genetic medicines. Our team integrates chemistry, payload design, formulation, and preclinical science to translate platform innovation into a pipeline of transformative therapies. We operate in a fast-paced environment where creative problem-solving and high-impact data drive decisions. The Role We are seeking a Principal/Senior Scientist with deep expertise in polymer-based nanoparticle characterization to lead our analytical efforts from the bench. This is a hands-on role focused on developing the methods that define our platform. You will serve as the Subject Matter Expert (SME) for biopolymer characterization, driving method development, early-stage QC, and the analytical documentation required to successfully navigate IND-enabling studies. The ideal candidate thrives at the interface of discovery and development, ensuring that our innovative chemistry is backed by robust, reproducible analytical methods. Key Responsibilities Method Development & Characterization Lead the development and optimization of analytical methods for polymer-based nanoparticles, with a heavy emphasis on GPC/SEC-MALS and HPLC. Characterize polymer molecular weight distributions, architecture, and purity to support formulation and process development. Translate early-stage "research" methods into robust, qualified procedures suitable for formal development. QC, Documentation & Compliance Establish and execute QC protocols for incoming polymers and nanoparticle batches; perform routine testing to support internal programs. Author and review technical documents, including method qualification reports, SOPs, and batch records. Ensure all analytical

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