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BreezeBio

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  • Office & Operations Coordinator (Part-time)

    South San Francisco, CA

    unspecified Salary not disclosed

    Office & Operations Coordinator (Part-time) South San Francisco, CA Office & Operations Coordinator (Part-time) Brisbane, CA About BreezeBio BreezeBio is an early-stage biotech company building a next-generation delivery platform for genetic medicines. Our team integrates chemistry, payload design, formulation, and preclinical science to translate platform innovation into a pipeline of transformative therapies. As we scale our platform toward the clinic, we are seeking a strategic leader to architect our analytical function and build the infrastructure necessary for long-term success. BreezeBio is seeking a highly self-motivated Office & Operations Coordinator to provide support to the Operations team. This position will be responsible for assisting the Operations Team in the daily activities 50% of office and 50% of the lab space. The ideal candidate will have an extreme attention to detail as well as the ability to juggle priorities. Key Responsibilities for Office: Provide high level and comprehensive administrative support to the executive leadership team (ELT) and the CEO including complex calendaring and detailed travel plans and agendas. Organize department meetings, and special events. Coordinate activities, set agendas, and summarize deliverables for meetings impacting ELT and the research leadership team (RLT). Manage administrative operations' communications and development activities for Sr. Operations Manager and SVP of Business Operations, including HR, IT, Facilities. Ability to develop, implement, understand general company operations, work flows, and procedures as appropriate. Ability to work autonomously to manage the office and keep everything running smoothly and effectively. Key Responsibilities for Operations: Responsible for ensuring the policies, infrastructure, and equipment

  • Office Coordinator (Part-time)

    South San Francisco, CA

    unspecified Salary not disclosed

    Office Coordinator (Part-time) South San Francisco, CA Office Coordinator (Part-time) Brisbane, CA About BreezeBio BreezeBio is an early-stage biotech company building a next-generation delivery platform for genetic medicines. Our team integrates chemistry, payload design, formulation, and preclinical science to translate platform innovation into a pipeline of transformative therapies. As we scale our platform toward the clinic, we are seeking a strategic leader to architect our analytical function and build the infrastructure necessary for long-term success. BreezeBio is seeking a highly self-motivated Office Coordinator to provide high-level administrative and operational support to our executive leadership team. This role is primarily office-focused, responsible for ensuring smooth day-to-day operations, managing executive priorities, and supporting cross-functional coordination across the organization. The ideal candidate is exceptionally organized, detail-oriented, and thrives in a fast-paced environment while managing multiple priorities with professionalism and discretion. Key Responsibilities: Executive & Administrative Support Provide high-level, comprehensive administrative support to the CEO and Executive Leadership Team (ELT), including complex calendaring, meeting coordination, and travel planning. Prepare detailed agendas, briefing materials, and follow-ups for executive meetings. Serve as a liaison between executives and internal/external stakeholders, maintaining professionalism and confidentiality. Draft, edit, and manage communications on behalf of leadership. Office Coordination & Operations: Oversee daily office operations to ensure a productive, organized, and efficient work environment. Coordinate company meetings, events, and team gatherings. Manage office vendors, supplies, and facilities-related needs. Support cross-functional initiatives across HR, IT, and Operations. Maintain and improve office processes, workflows, and administrative systems. Ensure office policies and procedures are

  • Principal Scientist / Senior Scientist, Analytical Chemistry (Biopolymers)

    South San Francisco, CA

    onsite Salary not disclosed

    Principal Scientist / Senior Scientist, Analytical Chemistry (Biopolymers) South San Francisco, CA Principal Scientist / Senior Scientist, Analytical Chemistry (Biopolymers) Location: Brisbane, CA (Onsite) About BreezeBio BreezeBio is an early-stage biotech company building a next-generation delivery platform for genetic medicines. Our team integrates chemistry, payload design, formulation, and preclinical science to translate platform innovation into a pipeline of transformative therapies. We operate in a fast-paced environment where creative problem-solving and high-impact data drive decisions. The Role We are seeking a Principal/Senior Scientist with deep expertise in polymer-based nanoparticle characterization to lead our analytical efforts from the bench. This is a hands-on role focused on developing the methods that define our platform. You will serve as the Subject Matter Expert (SME) for biopolymer characterization, driving method development, early-stage QC, and the analytical documentation required to successfully navigate IND-enabling studies. The ideal candidate thrives at the interface of discovery and development, ensuring that our innovative chemistry is backed by robust, reproducible analytical methods. Key Responsibilities Method Development & Characterization Lead the development and optimization of analytical methods for polymer-based nanoparticles, with a heavy emphasis on GPC/SEC-MALS and HPLC. Characterize polymer molecular weight distributions, architecture, and purity to support formulation and process development. Translate early-stage "research" methods into robust, qualified procedures suitable for formal development. QC, Documentation & Compliance Establish and execute QC protocols for incoming polymers and nanoparticle batches; perform routine testing to support internal programs. Author and review technical documents, including method qualification reports, SOPs, and batch records. Ensure all analytical

  • Associate Director / Director, Analytical Development

    South San Francisco, CA

    onsite Salary not disclosed

    Associate Director / Director, Analytical Development South San Francisco, CA Associate Director / Director, Analytical Development Location: Brisbane, CA (Onsite) About BreezeBio BreezeBio is an early-stage biotech company building a next-generation delivery platform for genetic medicines. Our team integrates chemistry, payload design, formulation, and preclinical science to translate platform innovation into a pipeline of transformative therapies. As we scale our platform toward the clinic, we are seeking a strategic leader to architect our analytical function and build the infrastructure necessary for long-term success. The Role The Director of Analytical Development will be a foundational member of the CMC leadership team. You will be responsible for the strategic vision and operational execution of BreezeBio's analytical department. This role requires a "builder" mindset: you will decide what capabilities we build in-house (CAPEX), what we outsource to CDMOs, and how we manage our onsite, non-regulated QC to support rapid platform iteration. You will bridge the gap between early-stage polymer discovery and formal development, serving as the primary analytical architect for our IND-enabling programs and beyond. Key Responsibilities Strategic Infrastructure & CAPEX Build the Lab: Define the internal analytical roadmap; identify and justify CAPEX requirements for essential instrumentation (e.g., advanced GPC-MALS, HPLC/SEC, Particle Characterization) to support onsite development. Make vs. Buy Strategy: Determine which analytical methods are critical for internal "high-touch" development and which are best suited for transfer to external partners. Onsite QC Oversight: Manage the internal, non-regulated QC function to ensure rapid, high-quality data turnaround for the chemistry and formulation teams. CDMO

  • Scientist I, Immunology

    South San Francisco, CA

    unspecified Salary not disclosed

    Scientist I, Immunology South San Francisco, CA Scientist I Location: South San Francisco, CA Position: Full-Time BreezeBio is a rapidly-growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works together across chemistry, payload design, formulation, and screening and preclinical groups to develop the next generation of gene therapies. BreezeBio fosters an exciting and dynamic environment where we value impactful data and creative solutions to accelerate our progression from a platform technology to a pipeline of therapeutic candidates. We are seeking talented and motivated individuals to join our team and are expanding across all functions within the organization. Join us in Brisbane, CA, to be at the forefront of the future of gene therapy. Position Summary We are seeking a talented and motivated Scientist to join our Immunology team and drive the development of genetic medicines for immune-based diseases utilizing our hydrophilic nanoparticle (HNP) technology. This individual will report to the Program Lead and will be responsible for assisting with planning and executing short and long-term R&D strategy for the Immune Program. She/he will be a key contributor to project and study design, method development, program strategy, and HNP and payload screening to identify lead therapeutic candidates that meet strict in vitro and in vivo target criteria for tissue and cell-specific delivery of nucleic acid payloads to achieve the desired immune modulating activity. The ideal individual will have a strong background in cellular immunology, immune modulation and tolerance,

  • Senior Consultant, CMC Development and Manufacturing

    South San Francisco, CA

    unspecified Salary not disclosed

    Senior Consultant, CMC Development and Manufacturing South San Francisco, CA BreezeBio is a rapidly-growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works together across chemistry, payload design, formulation, and screening and preclinical groups to develop the next generation of gene therapies. BreezeBio fosters an exciting and dynamic environment where we value impactful data and creative solutions to accelerate our progression from a platform technology to a pipeline of therapeutic candidates. We are seeking talented and motivated individuals to join our team and are expanding across all functions within the organization. Join us in South San Francisco, CA, to be at the forefront of the future of gene therapy. Senior Consultant, CMC Development and Manufacturing BreezeBio is looking for an individual who will provide technical and organizational leadership and work closely with cross-functional stakeholders to ensure CMC activities are executed seamlessly and in alignment with the integrated product development plan and program timelines. The individual will lead the management of manufacturing of established drug substances and drug products for late-phase clinical trials and the development of new products. The individual will also contribute to the overall CMC strategy, planning, and execution; provide regulatory documentation for all phases of clinical trials and commercialization; and play a role in CDMO management for other CMC areas including analytical and drug product. The senior consultant will be a contributing member of the R&D management team to plan and execute on company