Sr. Network and Infrastructure Engineer
Personalis INC - Fremont, CA
Posted Feb 6, 2026
Benefits
- Parental leave
- Not verified
- Non-birth-parent leave
- Not verified
- Family-building benefits
-
- Fertility benefits: Not verified
- Adoption assistance: Not verified
- Surrogacy assistance: Not verified
- Mental health support
- Not verified
- Relocation assistance
- Not verified
- Childcare support
- Not verified
- Learning budget
- Offered From the posting source checked Jun 20, 2026
- Verification
- Not verified checked Jun 13, 2026
- Salary
- $150K-$170K From the posting source checked Jun 20, 2026
- 401(k) match
- Reported from DOL Form 5500 industry filing (not employer-specific)
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Market context
- U.S. role benchmark (BLS OEWS)
- $116,543 U.S. median for this role
- Projected growth (BLS Employment Projections)
- +9.8% - Much faster than average
37% above the BLS role benchmark for software engineering aggregate.
Matched to SOC 15-1252 - Software Engineering aggregate by role bucket.
Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.
Role
Schedule
- Shift type
- Not verified
- Weekend work
- Not verified
Company
Application
- Cover letter
- Not verified
- Assessment
- Not verified
- Deadline
- Not stated
Where they hire
State eligibility is not yet verified.
About this role
Sr. Network and Infrastructure Engineer Fremont, CA At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California. Onsite: Monday, Tuesday & Thursday Summary: We are seeking a highly skilled and versatile Senior Network & Infrastructure Engineer to join our growing team. This role is designed for a technical "bridge" builder-someone who possesses deep expertise in high-performance networking (HPC) and Cisco security, but who is also comfortable managing a modern, hyperconverged infrastructure stack. The successful candidate will lead the architecture and maintenance of our Cisco Nexus fabric, secure our perimeter with NextGen firewalls, and support a robust environment consisting of VxRail, VMware, and petabyte-scale HPC storage. You will be equally at home in a CLI environment as you are performing hands-on hardware management within our colocation data centers. Responsibilities: Network & Security Architecture (60%) HPC Networking: Architect, deploy, and optimize Cisco Nexus switches within a High-Performance Computing (HPC) environment, ensuring low latency and high throughput. Security & Firewalls: Full lifecycle management of Cisco NextGen Firewalls (NGFW) . You
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Apply link verified; last checked Aug 3, 2026.
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