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Associate Director, Medicinal Chemistry

Maplight Therapeutics Inc - Remote

Posted May 4, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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Childcare support
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Learning budget
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Verification
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Salary
$180K-$205K Verified - from the job posting source checked Jun 20, 2026

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Market context

U.S. role benchmark (BLS OEWS)
$116,543 U.S. median for this role
Projected growth (BLS Employment Projections)
+9.8% - Much faster than average

U.S. benchmark only; posted salary is not compared across countries or currencies.

Matched to SOC 15-1252 - Software Engineering aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

Shift type
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Weekend work
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Company

Company stage
Public-company Verified - from the job posting source checked Jun 20, 2026
Equity
Offered Verified - from the job posting source checked Jun 20, 2026

Application

Cover letter
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Assessment
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Deadline
Not stated

Where they hire

State eligibility is not yet verified.

About this role

Associate Director, Medicinal Chemistry Remote Who We Are: MapLight Therapeutics is a clinical stage biotech company that focuses on drug discovery for central nervous system disorders. We combine cutting-edge technologies including optogenetics, in vivo physiology, and spatial transcriptomics to identify novel drug targets and develop effective therapies to address psychiatric symptoms. What You'll Do: We are searching for a highly motivated Medicinal Chemist to join our drug discovery team at the Associate Director level. Reporting to the Executive Director of Chemistry, the candidate will be expected to co-lead, or lead, preclinical medicinal chemistry programs from hit to candidate nomination. A highly qualified candidate will have experience in CNS drug discovery and an in-depth understanding of designing efficacious and safe brain-penetrant small molecules. While MapLight has in-house laboratories for pre-clinical research, many activities like chemical synthesis are outsourced to external vendors. Experience managing remote CRO teams, logistics across multiple partners, and coordinating internal drug discovery activities across different time zones is essential. This is a fantastic opportunity to join a small medicinal chemistry team and have a significant impact in addressing unmet patient needs by advancing MapLight's pipeline. Responsibilities: - Co-lead, or lead, preclinical medicinal chemistry programs from hit to candidate nomination. - Design and execute successful medicinal chemistry strategies to meet project and corporate goals. - Conduct multi-parameter optimization to deliver orally bioavailable, brain-penetrant candidates without secondary pharmacology, ADME, or safety concerns of initial hits. - Apply structure-based drug design principles utilizing in-house resources and external computational partners. - Manage

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