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Senior / Principal Scientist, AI for Protein Engineering

Lila Sciences - San Francisco, CA USA

Posted May 4, 2026

Benefits

Parental leave
Not verified
Non-birth-parent leave
Not verified
Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
Not verified
Relocation assistance
Not verified
Childcare support
Not verified
Learning budget
Offered From the posting source checked Jun 20, 2026
Verification
Not verified
Salary
$268K-$358K From the posting source checked Jun 20, 2026
401(k) match
Not verified

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Market context

U.S. role benchmark (BLS OEWS)
$55,390 U.S. median for this role
Projected growth (BLS Employment Projections)
-0.1% - Decline

465% above the BLS role benchmark for teaching and education aggregate.

Posted salary is far from this role benchmark; treat it as low confidence.

Matched to SOC 25-2021 - Teaching and Education aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function
Teaching Education From the posting source checked Jun 20, 2026
Seniority
Principal From the posting source checked Jun 20, 2026

Schedule

Shift type
Not verified
Weekend work
Not verified

Company

Company stage
Early From the posting source checked Jun 20, 2026
Equity
Offered From the posting source checked Jun 20, 2026

Application

Cover letter
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Assessment
Not verified
Deadline
Not stated

Where they hire

State eligibility is not yet verified.

About this role

Senior / Principal Scientist, AI for Protein Engineering San Francisco, CA USA Your Impact at LILA Lila is building a platform where AI and automation co-evolve to solve the hardest problems in medicine. Within Life Sciences AI (LSAI), the AI for Protein Engineering team develops and uses the generative and predictive models that drive Lila's biomolecule design programs from in silico hypothesis to wet-lab validated lead. We are seeking a Senior or Principal Scientist to join this team as a senior IC focused on antibody design and engineering. You will develop and execute the methods and workflows that ensure successful completion of antibody campaigns. Scope may expand to additional modalities such as enzymes and peptides as needs evolve. This role sits at the bilingual edge of ML and biology. You will own biological understanding of campaign needs and partner closely with the Life Science Research team to design and validate computational predictions in the lab. You will shape the technical agenda for AI protein engineering at Lila and represent that work both internally and to the broader research community. What You'll Be Building - Develop and own protein design and engineering workflows for antibody campaigns, including de novo design, affinity maturation, and developability optimization - Execute design workflows end-to-end for active campaigns and deliver wet-lab-validated leads against program milestones - Translate campaign requirements - epitope selection, affinity targets, biophysical constraints, and developability criteria - into well-defined ML problems and design specifications - Adapt and extend state-of-the-art AI methods (generative models,

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