Senior Manager, Analytical Development and QC, Small Molecule

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Not verified last checked Jun 13, 2026

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401(k) match

Listed Source: SMALL_EMPLR_CONTRIB_INCOME_AMT. source Last checked Jun 13, 2026.

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About this role

Senior Manager, Analytical Development and QC, Small Molecule Bothell, Washington, United States Company Overview Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been submitted to the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-3050, an IND-cleared FAP-targeted radiotherapy; and IM-1617, an IND-cleared solid tumor ADC. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets. Position Overview Immunome is seeking a highly experienced and collaborative Senior Manager, Analytical Development and QC, Small Molecule to lead analytical method development, validation, and quality control activities supporting our small molecule programs from early development through regulatory submissions and commercialization. The successful candidate will bring deep technical expertise in small molecule analytical chemistry, understanding of cGMP and ICH expectations, and proven experience operating in an outsourced development model with CDMOs and contract testing laboratories. Reporting to the Director, Analytical Development & QC, this individual will shape Immunome's small molecule analytical development and QC strategy and advance our oncology pipeline. Responsibilities Strategic Leadership - Develop and execute phase-appropriate analytical development and QC strategies for ADC linker payload components, small molecule intermediates, and drug substance, including specifications and control strategies. - Provide technical leadership for analytical method development, qualification, validation, and

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