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Executive Director, Early-Stage Program Team Leader

Immunome Inc - Bothell, Washington, United States

Posted May 19, 2026

Benefits

Parental leave
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Family-building benefits
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Salary
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401(k) match
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About this role

Executive Director, Early-Stage Program Team Leader Bothell, Washington, United States Company Overview Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been submitted to the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-3050, an IND-cleared FAP-targeted radiotherapy; and IM-1617, an IND-cleared solid tumor ADC. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets. Position Overview The Executive Director, Early-Stage Program Team Leader provides enterprise-level leadership for three or more strategically critical early-stage development programs spanning preclinical through early clinical development (Phase I/II). This role is accountable for defining and driving integrated program strategy, ensuring alignment with corporate objectives, portfolio priorities, and long-term value creation. This person will serve as the strategic and operational leader of cross-functional program teams, with authority to drive decisions, manage trade-offs, and escalate key investment considerations to executive governance forums. They will partner closely with senior functional leaders across Research, Clinical Development, CMC, Regulatory, and Commercial to ensure cohesive execution and disciplined portfolio advancement. This role represents the program(s) at executive leadership reviews and plays a key role in shaping portfolio strategy, resource allocation, and development prioritization. Responsibilities Enterprise Program Strategy & Portfolio Leadership - Define and drive integrated, end-to-end program

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