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Senior Engineer III, Small Molecules – High Throughput Screening & Technology

Ginkgo Bioworks - Boston, Massachusetts

Posted May 14, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
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  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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Childcare support
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Learning budget
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Salary
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401(k) match
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Market context

Median wage (BLS OEWS)
$111,944 national median
Projected growth (BLS Employment Projections)
+13.7% - Much faster than average

52% above the BLS national median for data and ml aggregate.

Matched to SOC 15-1252 - Data and ML aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

Shift type
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Weekend work
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Application

Cover letter
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Assessment
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Deadline
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Where they hire

State eligibility is not yet verified.

About this role

Senior Engineer III, Small Molecules – High Throughput Screening & Technology Boston, Massachusetts Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe's growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Senior Engineer III, Small Molecules - High Throughput Screening & Technology Location: Boston, MA Team: Datapoints - Small Molecule Developability & Functional Genomics Reporting to: Vice President, Small Molecules Role Overview We are hiring a Senior Engineer III, Small Molecules for a key technical leadership role owning Datapoints' high‑throughput small‑molecule and functional genomics screening capabilities. This person is a player-coach and the technical heart of the screening and automation workflows that enable ADME, Drug‑Seq, imaging/viability assays, and related workcell operations across Datapoints. You will design and run complex, automation‑enabled experiments, harden them into reliable platform workflows, and lead a small group of scientists/engineers (directly and indirectly) to deliver multiple programs in parallel. You will also balance scientific thought leadership (connecting the "why" to the "how/when") with an intense focus on operational excellence. Key Responsibilities - End‑to‑end ownership of screening workflows - Own HTS and Drug‑Seq‑linked workflows (workcell and walk‑up), including design, execution, QC, and data handoff. - Translate program objectives into executable workplans with realistic timelines and risk trade‑offs. - Assay & workflow development - Develop, optimize, and qualify phenotypic and viability assays (e.g., imaging + CTG, Drug‑Seq primary/secondary).

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