Stoke Therapeutics jobs

Director, Strategic Purchasing Bedford, Massachusetts, United States About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/ Position Purpose: We are seeking a Strategic Purchasing Director. In this newly created position, you will lead Stoke's strategic sourcing and procurement function as we continue to grow into a later stage clinical development and potentially commercial biotechnology company. Reporting to the VP, Controller, you will have the opportunity to establish this critical function and build it as the company grows. A key component of this role is to build and manage long-term, mutually beneficial vendor relationships that drive value and support the company's mission to address the underlying cause of severe diseases. Additionally, you will act as a strategic partner with functional business partners across the company, in particular clinical development, clinical

Pharmacovigilance Scientist Bedford, Massachusetts, United States About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/ Position Purpose: We are building our Pharmacovigilance department in support of ongoing clinical development activities and NDA submission for a first-in-class antisense oligonucleotide (ASO) therapy in a rare pediatric neurological disease. The PV Scientist is a newly created role and a genuine opportunity to shape the scientific infrastructure of PV department at a critical inflection point. The PV Scientist is accountable for overall PV science support for pharmacovigilance department at Stoke, which includes working in collaboration with the Safety Physician(s) and cross-functional teams to lead signal detection activities conducted in the safety governance model within the company. The ideal candidate will have deep PV science experience and will contribute across clinical and regulatory workstreams

Senior Director, Clinical Quality Compliance Bedford, Massachusetts, United States About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/ Position Purpose: The Sr. Director, Clinical Quality Compliance, will be responsible for overseeing all aspects of GCP and GCLP associated with the development, maintenance and oversight of activities related to Clinical Trials sponsored by Stoke. This role will report into The VP of Quality and will partner closely with other cross-functional groups such as Clinical Development, Clinical Development Operations, DMPK, Toxicology, Regulatory and other functions within Quality to embed GCP quality considerations into clinical development. This person will lead clinical quality strategy across Stoke's clinical programs. This role ensures global GCP and GCLP compliance (e.g., FDA, EMA, ICH etc.), provides guidance on clinical trial operations, and fosters a culture of quality,

Associate Director, HCP Marketing Bedford, Massachusetts, United States About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/ Position Purpose: The Associate Director, HCP Marketing will report to the Executive Director, Marketing. Along with the Executive Director of Marketing, you will be responsible for all HCP activities from disease education (DE) campaign development and deployment, as well as the creation of the branded campaign for the potential launch of zorevunersen. We are looking for someone with a particular expertise in non-personal marketing, but experience in others areas, such as KOL engagement, market research and congress strategy & execution, are a bonus. As a small company, we operate at a fast pace with many competing priorities so the ability to thrive in this type of requirement is essential. Key Responsibilities: Work

Vice President, Field Leader, Market Access Field National & Regional Bedford, Massachusetts, United States About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/ Position Purpose: The Executive Director/Vice President, Field Leader - Market Access Field National & Regional will be responsible for building and leading Stoke's market access organization, including Market Access Account Directors (MADs) and Field Reimbursement Managers (FRMs). This leader will develop and execute the field strategy to ensure broad, timely, and sustained access to Zorevunersen across payers and ensure provider sites are compliantly supported on reimbursement processes. The role will focus on establishing trusted relationships with national and regional payers, Commercial and Medicaid, along with healthcare providers to minimize barriers to patient access. As part of the Market Access leadership team, this individual will play a

Director, Financial Planning & Analysis (R&D) Bedford, Massachusetts, United States About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/ Position Purpose: The Director, Financial Planning & Analysis (R&D) will play a critical role in financial and strategic decision making at the Company, playing a key role in the future growth of the organization. The focus of this position will be to provide overall financial business partnering to the Research & Development (R&D) functions including leading the budgeting, forecasting and long-range planning processes, supporting the monthly and quarterly close process, providing monthly reporting to department leads and the Executive Leadership Team, supporting external collaborations, and performing ad hoc financial analysis. This person will work closely with team members, department heads and program teams to understand and manage the performance of

Sr. Medical Director, Pharmacovigilance Bedford, Massachusetts, United States About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/ Position Purpose: The Senior Medical Director, Pharmacovigilance will be responsible for the medical review of adverse event data, the development of company causality assessment frameworks in post-marketing surveillance, and leading signal detection and management activities. This individual will work in close partnership with PV operations to build rigorous, scalable, medical safety practices suited to a clinical development and complex postmarketing environment. This position will report into the Head of Pharmacovigilance. This is a role for a physician who is energized by developing business practice frameworks and review processes that a growing medical safety function requires and leading the medical safety domain within the organization. Rare disease carries meaningful responsibility to patient and

Director/Senior Director, Global Medical Information & Operations Bedford, Massachusetts, United States About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/ Position Purpose: Stoke Therapeutics is seeking an experienced and hands-on Medical Information leader to build, operationalize, and scale the Medical Information (MI) function in advance of commercialization. This role will have end-to-end ownership of Medical Information, including contact center strategy and operations, scientific response content, inquiry management, and development of a scalable, digitally enabled self-service medical information portal. This role requires strong operational rigor and a forward-looking mindset, with comfort working in ambiguity and establishing new ways of working. The ideal candidate brings a balance of scientific credibility, operational excellence, and curiosity about how Medical Information can continue to evolve in a growing organization. Key Responsibilities: Medical Information Strategy

Band 5 - Chemotherapy Nurse - Stoke-on-Trent Stoke-on-Trent

VodafoneThree - Incident Specialist Stoke on Trent, United Kingdom | ST1 5GP | Stoke-on-Trent ST1 5GP, UK

Occupational Hygiene & SHE Technician Stoke On Trent posted: Posted 24 Days Ago

Technical Writer Stoke on Trent posted: Posted 30+ Days Ago

Short-term Temporary Team Member - Stoke Talke Outlet (N119972) Stoke-On-Trent, Staffordshire, United Kingdom SHIFTS YOU ARE APPLYING FOR: 5.50hrs p/w; Sat 12:00 - 18:00

Short-term Temporary Team Member - Stoke Talke Outlet (N119974) Stoke-On-Trent, Staffordshire, United Kingdom SHIFTS YOU ARE APPLYING FOR: 5.50hrs p/w; Sat 09:00 - 15:00

Short-term Temporary Team Member - Stoke Talke Outlet (N119973) Stoke-On-Trent, Staffordshire, United Kingdom SHIFTS YOU ARE APPLYING FOR: 5.50hrs p/w; Sat 09:00 - 15:00

Short-term Temporary Team Member - Stoke Talke Outlet (N119970) Stoke-On-Trent, Staffordshire, United Kingdom SHIFTS YOU ARE APPLYING FOR: 5.50hrs p/w; Sat 11:00 - 17:00

Short-term Temporary Team Member - Stoke Talke Outlet (N119971) Stoke-On-Trent, Staffordshire, United Kingdom SHIFTS YOU ARE APPLYING FOR: 5.50hrs p/w; Sat 11:00 - 17:00

Industrial Engineer Stoke On Trent posted: Posted 22 Days Ago

Associate Director, Patient Services New York, NY Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain's biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X . About This Role Axsome Therapeutics is seeking an Associate Director, Patient Services to lead the establishment and growth of a new Patient Services Hub. This role will work closely with the Director, Patient Services for developing, implementing, and overseeing all aspects of the Hub's operations, ensuring efficient and seamless patient access to therapies and support services. This role requires a strong leader to build and manage the hub team, foster collaborative relationships, and drive continuous improvement within a fast-paced environment. This role will have close collaboration among, and provide ad hoc support to, Field Access and Patient Service functions within the Market Access team, as related to the HUB.

Clinical Sales Specialist (CS) - Flint, MI Flint, Michigan, United States For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases. Our commercial portfolio includes treatments for hypercortisolism and oncology, and the company has discovered more than 1,000 proprietary selective cortisol modulators and glucocorticoid receptor antagonists. With advanced clinical trials in patients with hypercortisolism, solid tumors, ALS and liver disease, Corcept is unlocking the power of cortisol modulation to help address some of the most devastating diseases patients face today. Corcept is headquartered in Redwood City, California. To learn more, visit www.corcept.com . The CS is accountable for implementing the sales strategies for approved products consistent with Corcept's compliance standards as well as all applicable legal requirements for those key targeted health care providers and hospital systems within an assigned territory. Responsibilities: - Build and develop professional relationships with influential high prescribers and thought leaders in the territory to enhance Corcept brand and product loyalty - Leverages expertise and knowledge of the therapeutic disease state, the marketplace, applicable competitors, industry, and cross-functional activities/plans to anticipate and effectively manage business opportunities and challenges - Develops and implements effective customer specific territory plans and communicates insights to internal stakeholders - Prioritizes time and effort to ensure optimal coverage of appropriate physician specialists based on opportunity and potential - Plan and participate in education programs and speaker dinner programs - Manage territory

HGV Driver Class 1 or Class 2 Stoke on Trent, Stoke On Trent, United Kingdom LGV C+E or C Drivers (HGV 1 or 2) based Stoke on Trent. Pay Rate: £45,000 (OTE) including driver bonus, shift premiums & overtime. Contract Type: Permanent (Full-Time). Hours: Contracted to work 42...

Senior Medical Director, Oncology Redwood City, California, United States For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases. Our commercial portfolio includes treatments for hypercortisolism and oncology, and the company has discovered more than 1,000 proprietary selective cortisol modulators and glucocorticoid receptor antagonists. With advanced clinical trials in patients with hypercortisolism, solid tumors, ALS and liver disease, Corcept is unlocking the power of cortisol modulation to help address some of the most devastating diseases patients face today. Corcept is headquartered in Redwood City, California. To learn more, visit www.corcept.com . Responsibilities: - Design and implement Phase I to III clinical studies - Develop and participate in the writing and review of protocols, investigator brochures, study reports and other clinical and regulatory documents - Provide scientific oversight for Company operational staff, CROs, and clinical trial sites in all areas related to the therapeutic programs - Act as a clinical subject matter expert for both Company team members and for external contacts related to the assigned therapeutic programs - Establish and approve scientific methods for design and implementation of applicable clinical protocols, data collection systems and final reports - Act to provide medical oversight and safety monitoring for ongoing clinical trials including participation in SAE reporting and serving on the safety committee - Play a key role in the analysis, interpretation and delivery of high-quality clinical data - Interact with

Senior Director, Regulatory Affairs - Netherlands Amsterdam, North Holland, Netherlands For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases. Our commercial portfolio includes treatments for hypercortisolism and oncology, and the company has discovered more than 1,000 proprietary selective cortisol modulators and glucocorticoid receptor antagonists. With advanced clinical trials in patients with hypercortisolism, solid tumors, ALS and liver disease, Corcept is unlocking the power of cortisol modulation to help address some of the most devastating diseases patients face today. Corcept is headquartered in Redwood City, California. To learn more, visit www.corcept.com . As the Senior Director of Regulatory Affairs, you will architect and lead international regulatory strategy and execution to support Corcept's international commercialization and expansion, starting with Europe. This role ensures all regional and local regulatory requirements are met in cooperation with Corcept functions responsible for clinical research, manufacturing, and commercialization. Staying attuned to the evolving regulatory environment, you will assess and communicate the impact of changes on business and product development programs. At times, you will directly represent Corcept with health authorities in Europe and elsewhere, as our expansion continues. Responsibilities: - Develop robust European regulatory plans, aligned with Corcept's global strategy, that lead to commercialization in new countries - Provide regulatory guidance regarding European health authorities and interactions, including EMA - Contribute and independently execute the filing plans for Europe in line with corporate, regional, and

Associate Director/Director, Regulatory Affairs New York, NY Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain's biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X . About This Role Axsome Therapeutics is seeking an Associate Director/Director, Regulatory Affairs. The role is responsible for managing assigned regulatory activities for the development and commercialization of Axsome's product candidates. The right candidate will have had prior experience in independently providing regulatory guidance to investigational and commercial products under oversight provided by the department head when needed. The Associate Director/Director is responsible for mentoring associates as appropriate. This role reports directly to the VP, Regulatory Affairs. This role is based at Axsome's HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully