Keros Therapeutics Inc jobs

Medical Director Lexington, MA (Hybrid) At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients. Job Summary: Keros is searching for a Medical Director to drive clinical development of assets in its pipeline. The ideal candidate will be a physician or medical provider with therapeutic area expertise, medical monitoring experience, and a general understanding of clinical drug development within the biopharmaceutical industry. The role requires medical and scientific oversight along with hands-on participation in all aspects of clinical trial execution, ensuring the safety of trial participants and the scientific integrity of the data collected. The Medical Director will also lead and participate in teleconferences with study Investigators, advisory meetings with key opinion leaders (KOLs), and interactions with Health Authorities, as indicated. A genuine interest in learning and understanding the science supporting the pipeline, an ability to work collaboratively in a highly matrixed multidisciplinary team setting, and a commitment to developing new treatments for patients in need are critical

Research Associate Co-Op, In Vitro Pharmacology Lexington, Massachusetts, United States At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients. Job Summary We are seeking a highly motivated Biology/Biochemistry Major Co-op to join our In Vitro Pharmacology team for a 6-month Research Associate position. As a co-op student, you will have the opportunity to collaborate with our experienced scientists and researchers, gaining valuable insights into the field of cell/molecular biology, and contributing to our ongoing drug discovery projects. Primary Responsibilities - Maintain and culture multiple cell lines - Participate in protocol development and optimization of cellular assays - Conduct reporter assays to assess cellular signaling events - Regularly perform gene expression, protein detection analysis - Maintain accurate and detailed laboratory records - Collaborate with team members on research projects Core Competencies (Required Skills) - Previous training in cell/molecular biology laboratory skills and familiarity with cell culture techniques Preferred Skills - Excellent attention to detail and organizational skills -

Contract Process Development Associate II Lexington, Massachusetts, United States At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients. This role is responsible for providing overall support in early stages of process development and acting as an interface with the Research and CMC organizations. This person will be responsible for executing and developing stage appropriate downstream processes for novel protein therapeutics. Developing downstream purification processes for expression scales that range from shake flasks to pilot scale bioreactors. Theis person will also be involved in providing and analyzing data and relevant information for reports supporting tech transfer activities for external manufacturing. Responsibilities: - Hands-on execution, and optimization of protein purification processes including primary recovery unit operations (centrifugation, homogenization, flocculation, tangential-flow filtration (TFF), and depth filtration), chromatography (ion-exchange, affinity, hydrophobic interaction), and pre-formulation (TFF, dialysis) - Generate and analyze process and analytical data supporting key documents such as development reports, regulatory submissions, and technology transfer packages - Execute routine scale

Senior Research Associate I, Bioanalytical Lexington, Massachusetts, United States At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients. Job Summary: Keros is seeking a Senior Research Associate with working knowledge of large molecule/ biologics bioanalytical techniques and laboratory skills. This person will develop and perform bioanalytical methods for programs in preclinical and clinical development, document the methods used, interpret, and summarize the data collected. This role will report into the Bioanalytical Scientist and will be responsible for activities related to the development, qualification and bio-analysis for non-regulated methods and samples in support of drug candidate development. This individual will have the opportunity to directly contribute to the bioanalytical assay development for platform and therapeutic areas, and work in a fast-paced environment as part of a highly collaborative team. This is a full-time laboratory position based in Lexington, MA. Primary Responsibilities: - Design, develop, optimize, and execute bioanalytical assays to support nonclinical studies, including PK, PD, biomarker, and

Join our Talent Community Lexington, Massachusetts, United States At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients. Don't see a job posting that fits your background? That's OK. Please apply below to be considered for future opportunities. Our Diversity, Equity & Inclusion Mission Statement: Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members. Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law. Recruitment & Staffing Agencies: Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any

Contract Research Associate II, Protein Science Lexington, Massachusetts, United States At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients. Keros Therapeutics is seeking a highly motivated and collaborative individual to join our protein biochemistry group within our Research Department. Our group exploits multidisciplinary approaches in protein sciences and protein engineering, to better the understanding of the biochemical, biophysical, and structural functional properties of the biomolecules within the TGF-β superfamily that drive the signaling pathway. Our efforts greatly contribute to advance innovative research and drug discovery and heavily support our discovery pipeline. You will have the opportunity to learn about and contribute to early-stage drug discovery from a protein chemistry perspective as well as through internal and external collaboration with other departments. You will play an important role supporting in vivo and in vitro studies crucial for the progress of our therapeutic research programs by generating high-quality proteins and other reagents in this hands-on laboratory position. The successful

Director, Regulatory Operations Lexington, MA (Hybrid) At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients. Job Summary: Reporting to the Head Regulatory Affairs, the Director of Regulatory Operations will be responsible for establishing the Regulatory Operations role at Keros. This individual will leverage their extensive knowledge of Regulatory Operations to support Keros' growing regulatory needs including inhouse publishing as well as working with multiple external vendors. Primary Responsibilities: - Oversee all Regulatory Operations deliverables, including management of Health Authority correspondence/submission archives, business administration of the Veeva Vault Regulatory Information Management system, submission management, and training of associated business processes - Implement training strategies, develop training materials, and lead training delivery for effective adoption of Vault RIM - Manage user groups and workflows and create and maintain archives of Health Authority interactions - Develop, manage, and distribute reports, dashboards, and templates to meet user needs - Contribute to the writing, review, and implementation of standards and procedures related

Therapeutic Area Lead Vaccines & Infectious Diseases POL - Mazowieckie Wojewodztwo - Warsaw (Trade Center) posted: Posted 2 Days Ago

Therapeutic Area Head – Respiratory Remote About Apogee Therapeutics Founded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. At Apogee, you can actively contribute to shaping the company culture, take on various roles and responsibilities, and grow professionally. Apogee Therapeutics is a clinical-stage biotechnology company advancing novel biologics with potential for differentiated efficacy and dosing in the largest I&I markets, Apogee's antibody programs are designed to overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. Zumilokibart (APG777), the company's most advanced program, is being initially developed for the treatment of atopic dermatitis (AD), which is the largest and one of the least penetrated I&I markets, as well as asthma. With four validated targets in its portfolio, Apogee is seeking to achieve best-in-class efficacy and dosing through monotherapies and combinations of its novel antibodies. Based on a broad pipeline and depth of leadership and expertise, the company believes it can deliver value and meaningful benefit to patients underserved by today's standard of care. We are a fast-paced company committed to building an exceptional culture, founded on our C.O.R.E. values: C aring, O riginal, R esilient and E goless and a commitment to refusing to stop at “good enough”. If this sounds like you, keep reading! Role Summary We are seeking a Therapeutic Area (TA) Head, Respiratory - Clinical Development. In this

Principal Scientist, Peptide Therapeutics South San Francisco, California, United States of America This is a primarily lab-based, technical leadership position within the Peptide Therapeutics department. In this lab-based leadership role, you will combine hands-on synthetic expertise with strategic...

Associate Therapeutic Development Manager HKG - Hong Kong Island - Hong Kong (Lee Garden Two) posted: Posted 16 Days Ago

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Manager, Market Intelligence and Strategy Boston, MA The Organization What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. Through proprietary and versatile approaches, Entrada is advancing a robust development portfolio of genetic medicines for the potential treatment of neuromuscular and inherited retinal diseases, among others. Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne muscular dystrophy (DMD) who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered with Vertex Pharmaceuticals to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1 (DM1). 2026 represents a catalyst-rich period for Entrada. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51). These programs are complemented by the ongoing clinical progress of our DM1 collaboration with Vertex (VX-670). We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families. The Perfect Addition to Our Team You are interested in working at the intersection of life sciences and business. You want to join a high

Senior/Executive Director, Health Economics & Outcomes Research (HEOR) Viking Therapeutics, Inc. Senior/Executive Director, Health Economics & Outcomes Research (HEOR)

Executive Director, Investor Relations Boston, MA The Organization What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. Through proprietary and versatile approaches, Entrada is advancing a robust development portfolio of genetic medicines for the potential treatment of neuromuscular and inherited retinal diseases, among others. Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne muscular dystrophy (DMD) who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered with Vertex Pharmaceuticals to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1 (DM1). 2026 represents a catalyst-rich period for Entrada. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51). These programs are complemented by the ongoing clinical progress of our DM1 collaboration with Vertex (VX-670). We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families. The Perfect Addition to Our Team You are intellectually curious and can bring new ideas and perspectives to lead the development, implementation, and management of our

Associate Director, Formulation Development Viking Therapeutics, Inc. Associate Director, Formulation Development

Executive Director, Medical Affairs - Eosinophilic Esophagitis (EoE) Remote About Apogee Therapeutics Founded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. At Apogee, you can actively contribute to shaping the company culture, take on various roles and responsibilities, and grow professionally. Apogee Therapeutics is a clinical-stage biotechnology company advancing novel biologics with potential for differentiated efficacy and dosing in the largest I&I markets, Apogee's antibody programs are designed to overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. Zumilokibart (APG777), the company's most advanced program, is being initially developed for the treatment of atopic dermatitis (AD), which is the largest and one of the least penetrated I&I markets, as well as asthma. With four validated targets in its portfolio, Apogee is seeking to achieve best-in-class efficacy and dosing through monotherapies and combinations of its novel antibodies. Based on a broad pipeline and depth of leadership and expertise, the company believes it can deliver value and meaningful benefit to patients underserved by today's standard of care. We are a fast-paced company committed to building an exceptional culture, founded on our C.O.R.E. values: C aring, O riginal, R esilient and E goless and a commitment to refusing to stop at “good enough”. If this sounds like you, keep reading! Role Summary We are seeking a strategic, highly experienced Executive Director, Medical Affairs

Director of Process Validation Viking Therapeutics, Inc. Director of Process Validation

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Vice President, Pharmaceutical Development Watertown, MA Who we are: Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients' lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston's top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn . How we work: - PIONEER : We are courageous, resilient and rigorous in our mission to improve patients' lives through our revolutionary degrader medicines. - COLLABORATE : We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine. - BELONG : We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard. How you'll make an impact: - Define and lead the company's pharmaceutical development strategy across the portfolio, ensuring alignment with corporate priorities and development timelines - Provide strategic leadership for preformulation, biopharmaceutics, and formulation development activities supporting discovery, preclinical, and clinical-stage programs - Champion innovation in formulation sciences and enabling technologies to

Vice President, Marketing Watertown, MA Who we are: Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients' lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston's top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn . How we work: - PIONEER : We are courageous, resilient and rigorous in our mission to improve patients' lives through our revolutionary degrader medicines. - COLLABORATE : We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine. - BELONG : We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard. How you'll make an impact: As we prepare for the potential launch of KT-621, a novel oral protein degrader being developed for immune-mediated diseases, we are seeking an experienced and strategic leader to prepare the organization for Kymera's first commercial launch. The position will be responsible for leading commercial strategy, launch readiness, and

Multimedia Journalist, KERO Bakersfield, CA - KERO posted: Posted Yesterday

Executive Director / Vice President, Corporate and Internal Communications - BioPharma Remote About Us We are developing potentially best in class therapies for patients living with severe autoimmune diseases. Our lead antibody, claseprubart (DNTH103), is purposefully engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein that drives disease pathology - enabling less frequent and more convenient self-administered subcutaneous injections. Our second clinical candidate, DNTH212 is a first and potentially best in class, bifunctional inhibitor that targets clinically validated and complementary disease modifying mechanisms, Type 1 IFN suppression and B cell modulation - enabling potential for improved clinical outcomes and patient friendly convenient, self-administered subcutaneous injections. To learn more, please visit www.dianthustx.com and follow us on LinkedIn . About the Role BioPharma Experience is required. We are seeking a strategic, creative, and execution-oriented ED / VP, Corporate & Internal Communications to build and lead a modern, high-impact communications function in a fast-growing biotech company. This role sits at the intersection of people, corporate brand, and business strategy-responsible for shaping how we communicate internally and externally, strengthening employee engagement, elevating our corporate brand, and ensuring a consistent and compelling company narrative across all audiences, while operating as predominantly a remote company. You will serve as a trusted advisor to senior leadership and partner closely with the VP of Marketing and VP of Investor Relations to ensure alignment across corporate and internal communications. We are building a culture of individuals who hold our core principles at