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Member of the Technical Staff, Cheminformatics

Output Biosciences - New York HQ 🗽 | Remote

Posted Jun 10, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
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  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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401(k) match
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Market context

U.S. role benchmark (BLS OEWS)
$116,543 U.S. median for this role
Projected growth (BLS Employment Projections)
+9.8% - Much faster than average

Matched to SOC 15-1252 - Software Engineering aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

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Weekend work
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Application

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Assessment
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Deadline
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Where they hire

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About this role

Member of the Technical Staff, Cheminformatics New York HQ 🗽 | Remote The Role Output has built a biological reasoning model that understands biology at the scale and complexity life actually operates. Our model independently learned the principles of molecular interactions, opening up drug treatments that were previously impossible. We're already generating therapies that traditional approaches cannot reach. The hardest problems in both AI and biology are being solved here, and there is room for you to own one. Output is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI x Bio, and backed by top-tier VCs including Y Combinator. You accelerate the path from a generated molecule to a synthesized compound. This role continues to build the models and computational methods that optimize Output's molecular generation for practical chemistry. - You will continue developing and training models that incorporate knowledge of chemical synthesis routes and reactions, steering molecular generation toward molecules that are efficient to synthesize - You will build scalable computational tools and methods that evaluate synthetic feasibility across generated molecular libraries, systematically and at scale - You will interpret model inputs and outputs in chemistry terms, translating between the language of generative AI and the language of synthesis - You will work with the drug discovery and model teams, bringing chemistry expertise to molecular evaluation and candidate prioritization - You will build and maintain cheminformatics pipelines for molecular analysis, property calculation, and candidate assessment About You You have

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