Head of Biology
Output Biosciences - New York HQ 🗽
Posted Jun 10, 2026
Benefits
- Parental leave
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- Non-birth-parent leave
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- Family-building benefits
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- Fertility benefits: Not verified
- Adoption assistance: Not verified
- Surrogacy assistance: Not verified
- Mental health support
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- Relocation assistance
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- Childcare support
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- Learning budget
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- Salary
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- 401(k) match
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Schedule
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- Weekend work
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Application
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- Assessment
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- Deadline
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Where they hire
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About this role
Head of Biology New York HQ 🗽 The Role Output has built a biological reasoning model that understands biology at the scale and complexity life actually operates. Our model independently learned the principles of molecular interactions, opening up drug treatments that were previously impossible. We're already generating therapies that traditional approaches cannot reach. The hardest problems in both AI and biology are being solved here, and there is room for you to own one. Output is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI x Bio, and backed by top-tier VCs including Y Combinator. You own the feedback loop between Output's models and the lab. You go deep into specific biological problems, translate what the biology requires into priorities for data and modeling, and manage through CRO partners the experimental cycle that validates model outputs and generates new data. - You will own the active learning cycle between Output's models and experimental validation: designing experiments, managing CRO partners for synthesis and testing, interpreting results, and feeding them back to improve the models - You will dive into specific biological problem areas, developing the expertise needed to translate nuanced biological requirements into priorities for data construction, modeling, and evaluation - You will manage CRO relationships for peptide and molecular synthesis, biological assays, and experimental testing, designing each campaign to generate maximally informative data - You will collaborate with the engineering team to design and build biology-specific agent skills and workflows, encoding
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