Information Systems Security Manager (ISSM)

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About this role

Information Systems Security Manager (ISSM) Santa Clara, CA or Remote Thanks for your interest in Oklo! We are searching for an Information Systems Security Manager (ISSM) to join our team. Position Description The Information Systems Security Manager (ISSM) at Oklo, Inc. reports to the Senior Manager of IT and Cyber and is responsible for the implementation, operation, and continuous improvement of Oklo's information system security program. This role owns the day-to-day security posture of Oklo's information systems, ensuring confidentiality, integrity, and availability while maintaining compliance with applicable regulatory frameworks, including NIST 800-53, NIST 800-171, and DOE export control requirements under 10 CFR Part 810. The ISSM is a hands-on security leader who bridges technical execution with compliance rigor. This role partners closely with IT, engineering, legal, and compliance stakeholders to ensure secure system design, secure operations, and audit readiness across Oklo's rapidly evolving technology environment. This position is ideal for someone who thrives in a fast-paced startup, enjoys building and operating security programs, and is motivated by protecting mission-critical systems that support advanced nuclear energy innovation. Specific responsibilities may include: Information System Security Management - Serve as the primary authority for the security posture of Oklo's information systems. - Implement, maintain, and continuously improve information system security controls in alignment with NIST 800-53 and NIST 800-171. - Ensure security requirements are embedded into system design, configuration, and operations across on-premises and cloud environments. - Implement, assess, and remediate system configurations against security baselines and hardening standards, including DISA STIGs and

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