Principal Software Engineer, Instrument Simulations

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About this role

Principal Software Engineer, Instrument Simulations Cambridge, MA USA Your Impact at LILA Lila Sciences is seeking a Principal Software Engineer, Instrument Simulations to architect and lead the development of our next-generation laboratory automation platform. In this role, you'll be responsible for designing the simulation infrastructure and integration layer that connects AI-driven experimental design with physical robotic systems, enabling closed-loop scientific discovery at unprecedented scale. What You'll Be Building - Architect and implement high-fidelity simulation environments that model complex laboratory instrumentation, fluidics, and robotic workflows - Design robust integration patterns between heterogeneous hardware systems, ensuring reliable and safe execution of fully automated experiments - Lead the development of APIs and interfaces that enable scientists and AI agents to seamlessly interact with sophisticated automation infrastructure - Maintain and help establish best practices for hardware-software integration, system monitoring, and CI/CD in laboratory automation contexts for all newly developed systems - Mentor engineers, likely leading a small agile team What You'll Need to Succeed - Bachelor's or Master's degree in Computer Science, Engineering, or a related field: Background that supports technical and leadership capabilities. - 10+ years of software development experience, including 5+ years in a leadership role: Demonstrates ability to lead and manage complex projects and engineering teams. - Proven experience in architecting and directing large-scale software projects: Skilled in designing and leading the development of scalable, reliable, and maintainable systems. - Strong proficiency in programming languages such as C++, Python, or Java: Capable of setting technical standards and guiding development practices. -

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