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Senior Software Backend Engineer, Platform Computing

Iambic Therapeutics - San Diego HQ, San Diego, California, United States, Boston Office

Posted May 18, 2026

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About this role

Senior Software Backend Engineer, Platform Computing San Diego HQ, San Diego, California, United States, Boston Office JOB SUMMARY We are seeking a Senior Software Backend Engineer, Platform Computing to integrate and operate the compute layer that powers data processing and model inference across Iambic's drug discovery platform. You will work within the Software Platform team, partnering with ML engineers and scientists to ensure production workloads are reliable, performant, and scalable. Your focus will be on integrating and operating compute infrastructure and orchestration systems that enable scientific workflows across the platform. This position will be based at our San Diego Headquarters. KEY RESPONSIBILITIES - Integrate and maintain the compute layer supporting data processing and model inference workflows in production - Ensure reliable and performant execution of workloads through monitoring, troubleshooting, and failure resolution - Operate and extend workflow orchestration systems (e.g., Prefect, Coiled, Modal or similar frameworks) - Support deployment and execution of ML model outputs in production environments - Enable scientific workflows by integrating external data sources and supporting analysis and inference workloads within and outside of Insight (e.g., large-scale assay refits) - Collaborate with ML engineers and cross-functional teams to translate model capabilities into production-ready systems - Integrate new compute capabilities into the platform as they are developed, ensuring scalability and flexibility - Establish and maintain best practices for reliability, observability, and operational support QUALIFICATIONS - 10+ years of relevant experience with a Bachelor's degree; or 8 years and a Master's degree; or equivalent experience - Strong software engineering

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