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Associate Director/Director, Biology (Oncology Drug Discovery)

Iambic Therapeutics - San Diego HQ, San Diego, California, United States

Posted Apr 15, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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Childcare support
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Learning budget
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Salary
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401(k) match
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Market context

U.S. role benchmark (BLS OEWS)
$81,444 U.S. median for this role
Projected growth (BLS Employment Projections)
+6.9% - Faster than average

Matched to SOC 29-1141 - Healthcare aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function
Healthcare From the posting source
Seniority
Staff Plus From the posting source

Schedule

Shift type
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Weekend work
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Application

Cover letter
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Assessment
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Deadline
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Where they hire

State eligibility is not yet verified.

About this role

Associate Director/Director, Biology (Oncology Drug Discovery) San Diego HQ, San Diego, California, United States JOB SUMMARY Iambic Therapeutics is seeking a highly motivated and experienced Associate Director or Director to lead oncology drug discovery efforts and advance our core mission of accelerating small molecule drug discovery through the integration of experimental and AI/ML-driven approaches. The successful candidate will have a proven track record of driving oncology drug discovery programs and will lead project teams with a deep understanding of the progression of drug candidates from hit identification to IND submission. This role will set scientific direction and drive cross-functional collaboration with Chemistry, DMPK, Safety, and Computational teams. This position is based at our San Diego headquarters. IMPACT & SCOPE - Partner with Iambic's computational and ML scientists to incorporate AI/ML-based tools and models that accelerate data interpretation, hypothesis generation, and decision-making across biology workflows. - This is a high-impact role that influences portfolio strategy and progression. KEY RESPONSIBILITIES - Program leadership: Initiate, direct, and execute biology plans that support medicinal chemistry and translational goals across discovery stages (hit-to-lead, LO, candidate selection, IND-enabling). - Cross-functional integration: Chair or co-lead cross-functional workstreams; align assay strategy with SAR hypotheses, DMPK/PD needs, and safety/translational biomarkers. - Collaboration leadership: Lead or co-lead key scientific collaborations with internal and external partners, driving integration of data and strategy toward shared objectives. - Assay strategy & data integrity: Conceptualize and oversee the design and validation of in vitro and ex vivo assays (signaling, binding, trafficking, imaging, and mechanism

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