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Fullstack Software Engineer (Senior / Staff)

Genesis Molecular AI - San Mateo, CA, New York, NY

Posted Mar 3, 2026

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About this role

Fullstack Software Engineer (Senior / Staff) San Mateo, CA, New York, NY Fullstack Software Engineer (Senior / Staff) Genesis Molecular AI is building a world-class software team to solve problems in drug discovery through machine learning, biophysical simulation, and computational chemistry. We are looking for engineers excited to help develop new medicines and play a critical role in building out our software platform. You will - Own and evolve the full-stack platform that computational chemists use daily, from data exploration and experiment management to real-time visualization, shipping AI-native workflows and modern interaction patterns that shorten the loop between hypothesis and insight - Build and expand tools for visualizing molecules and proteins, analyzing ML models, and managing complex chemical workflows - Partner with machine learning engineers and computational chemists to develop and productionize new computational methods for molecular property prediction - Scale our data infrastructure to handle billions of datapoints and thousands of parallel deep learning and molecular dynamics jobs You are - A deep thinker who reasons from first principles, balances attention to detail with architectural thinking, and has an investigative curiosity to find the root cause of a problem - Comfortable owning problems across the entire stack - frontend interfaces, backend services, data pipelines, and infrastructure - Experienced shipping production code and driving projects end-to-end with minimal hand-holding - Excited to work at the intersection of software engineering, drug discovery, and machine learning What we offer - The opportunity to work on high impact tools and products that are

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