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Director, Program Management Office

Alkermes - Waltham, MA, United States

Posted Feb 4, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
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Mental health support
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Relocation assistance
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Childcare support
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Learning budget
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Verification
Not verified last checked Jun 13, 2026
Salary
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401(k) match
Listed Source: EMPLR_CONTRIB_INCOME_AMT. source Last checked Jun 13, 2026.

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Schedule

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Weekend work
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Application

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Deadline
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Where they hire

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About this role

Director, Program Management Office Waltham, MA, United States Alkermes is seeking an experienced Program Manager to support our ALKS 2680 program which is currently in Phase 2 development and preparing for Phase 3 and registration. ALKS 2680 is a novel, investigational, oral, selective orexin 2 receptor (OX2R) agonist in development as a once-daily treatment for narcolepsy and idiopathic hypersomnia. This person will work closely with members across our organization including areas such as research, pre-clinical, clinical, pharmaceutical development, regulatory affairs, medical affairs, commercial, operations, policy and government affairs, patient engagement and corporate communications, as well as the senior management team to orchestrate development and execution of our fully-integrated program strategic and operational plans to support key corporate goals including the development and ultimate approval of ALKS 2680 as well as identify and execute a comprehensive lifecycle management program. This is a hybrid on-site position based at our Waltham, MA office. Areas of responsibility will include: Facilitates development and execution of fully-integrated program strategic and operational plans, including: Development of program strategy, business objectives, activities to achieve these, and potential constraints with team recommendations for how to address Identifies cross-functional linkages/potential gaps, supports team with optimization of plans and execution Given the phase of this program the ideal candidate will have previous experience with late-stage development and registration submission preparation and support Proactive management of project execution as well as facilitating and maintaining comprehensive risk management plans Provides strong project management support to ensure issues are resolved by the team and

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