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Scientist II, ADC/AOC Conjugation

AbbVie Inc. - Worcester, MA, United States

Posted Jun 10, 2026

Benefits

Parental leave
12 weeks Source: https://www.abbvie.com/join-us/life-at-abbvie/well-being-in-the-workplace.html. source Last checked May 7, 2026.
Non-birth-parent leave
12 weeks Source: https://www.abbvie.com/join-us/life-at-abbvie/well-being-in-the-workplace.html. source Last checked May 7, 2026.
Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
Not verified
Relocation assistance
Not verified
Childcare support
Not verified
Learning budget
Not verified
Verification
Source-linked last checked May 7, 2026
Salary
Not verified
401(k) match
Listed Source: EMPLR_CONTRIB_INCOME_AMT. source Last checked May 7, 2026.

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Market context

U.S. role benchmark (BLS OEWS)
$111,944 U.S. median for this role
Projected growth (BLS Employment Projections)
+13.7% - Much faster than average

Matched to SOC 15-1252 - Data and ML aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

Shift type
Not verified
Weekend work
Not verified

Application

Cover letter
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Assessment
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Deadline
Not stated

Where they hire

State eligibility is not yet verified.

About this role

Scientist II, ADC/AOC Conjugation Worcester, MA, United States Company Description: About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube. Job Description: Key Responsibilities: Synthesis, purification, and characterization of antibody drug conjugates (ADCs) and antibody oligonucleotide conjugates (AOCs) on mg to gram scale under minimal supervision. Development, optimization, and validation of conjugation protocols specifically for antibody oligonucleotide conjugates. Optimization and validation of formulation buffers for bioconjugates. Lead application and refinement of automated techniques for ADC/AOC synthesis and purification. Collaboration with cross-functional teams to advance ADC/AOC discovery programs from conceptualization to early development. Qualifications: Qualifications B.S. degree with 7 years of experience or M.S. degree with 5 years' experience in Biochemistry, Organic, Bioorganic or Analytical Chemistry, Molecular Biology, or related field. Demonstrated hands-on expertise in laboratory-scale protein purification using Hydrophobic Interaction Chromatography (HIC), Size Exclusion Chromatography (SEC), Ion-Exchange (IEX), mixed-mode chromatography, and/or affinity chromatography. Experience with GE AKTA FPLC and Unicorn software is preferred. Hands-on experience with relevant analytical techniques such as HIC-HPLC, SEC, IEX, RP-HPLC, LCMS and capillary electrophoresis techniques (e.g., CE-SDS, icIEF). Strong experience in the discovery, design, synthesis, and purification

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