Mirum Pharmaceuticals Inc jobs

Patient Navigator Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY Are you someone who has the proven ability to thrive in a dynamic, evolving environment and contribute to building new capabilities in healthcare. We're seeking an empathetic, detail-driven Patient Navigator to join our growing rare disease team. In this pivotal role, you'll serve as the primary liaison for patients, caregivers, and healthcare providers, ensuring a seamless experience from prescription to ongoing therapy. You will provide inbound and outbound phone support and serve as the primary contact for patients, caregivers, and providers. You will facilitate a collaborative process that gauges, coordinates, and monitors patient need and appropriately facilitates a patient's journey utilizing services offered through the Patient Support Program on behalf of Mirum and coordination with our specialty pharmacy partner. You'll work closely with the specialty pharmacy, reimbursement specialists, and internal partners to make sure patients receive their medications on time, every time. The outcome of your efforts will be providing unparalleled customer service to patients, caregivers and, providers. If you have a nursing or case management background, can thrive in a fast-paced biotech environment, and are passionate about helping patients with rare diseases

Medical Science Liaison, Florida US Remote MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The medical science liaison (MSL) is a field-based Medical Affairs professional who is primarily responsible for establishing and maintaining relationships with thought leaders and other healthcare professionals (HCPs) as well as engaging in scientific exchange in their assigned territory. This individual will also serve as a scientific resource and scientific expert in the support of Mirum's rare disease liver portfolio. This includes medical affairs and related activities such as medical congress staffing, advisory boards and cross-collaborative initiatives. We are looking for someone living in Florida. Field Medical territory is Florida and Puerto Rico. No relocation will be offered for this role. JOB FUNCTIONS/RESPONSIBILITIES - Identifies, can gain access to, and develops professional relationships with thought leaders and other healthcare professionals, active and potential study investigators, and professional organizations within their assigned geography - Supports research initiatives across development and provides support to clinical site investigators - Serve as a liaison between HCPs who express interest in conducting investigator-initiated research to facilitate review and consideration of research proposals - Engages in scientific exchange in response to HCP requests - Can effectively articulate

Director, Clinical Development Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Director/Senior Director, Clinical Development will be responsible for all clinical trial related activities for Brelovitug, a key asset in Phase 3 on a cross-functional team of internal and external experts, investigators and government agencies. Activities include but are not limited to protocol development, support study startup, oversight of trial execution, recruitment, ongoing clinical development management and closeout as appropriate. Compliance with internal processes, GCP/ICH and regulatory requirements, study and data monitoring, data analysis are required. Participation in health authority meetings and regulatory filing activities are also part of this role. The Director/Senior Director, Clinical Development operates in collaboration with other functions including internal Safety, Regulatory, Biometrics, and Clinical Operations teams. JOB FUNCTIONS/RESPONSIBILITIES - Leadership and management of all aspects of complex, global development clinical studies. - Primary point of contact for clinical inquiries from sites, CRO and site monitors; answer or triage questions as appropriate integration of clinical/regulatory strategy into global product development strategy. - Primary liaison for internal Clinical Operations for site selection, site start-up activities, study management and closeout activities, etc. - Support the creation of and/or review of

Senior Specialist, Clinical Supply Chain Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSTION SUMMARY Reporting to the Executive Director, Clinical Supply Chain, the Senior Specialist is responsible for supporting the senior team members in managing the global supply and distribution of investigational drug product for Mirum's ongoing clinical trials inclusive of the oversight management of multiple Contract Manufacturing Organizations (CMOs) and distribution providers. The ideal candidate is a detailed oriented, self-starter, proactive, with the ability to work independently under minimal supervision. JOB FUNCTIONS/RESPONSIBILITIES - Supports the development and execution of Clinical Supply strategies for all Mirum investigational drug products in collaboration with senior team members. - Assists in creating and maintaining the Clinical Supply forecasting models to ensure investigational material production aligns with corporate and financial goals, study enrollment, and business continuity. - Supports Clinical Supply program activities for investigational drug product inventory management and distribution in partnership with CMOs; evaluates drug utilization versus forecast considering country requirements and logistical timelines. - Provides support for the oversight of Clinical Supply CMOs, including assisting in selection (RFI), contract negotiations, financial review, daily operations, and routine assessment of CMO performance via formal Business Reviews. - Assists

Director, Clinical Development Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Director, Clinical Development will join the Clinical Development group and will be responsible for all clinical trial related activities in all stages of clinical development in a cross-functional team of internal and external experts, investigators and government agencies. Activities include but are not limited to protocol development, support study startup, oversight of trial execution, recruitment, ongoing clinical development management and closeout as appropriate. Compliance with internal processes, GCP/ICH and regulatory requirements, study and data monitoring, data analysis, are required. Participation in health authority meetings and regulatory filing activities are also part of this role. The Director, Clinical Development, operates in collaboration with other functions including internal Safety and Clinical Operations teams. JOB FUNCTIONS/RESPONSIBILITIES - Leadership and management of all aspects of complex, global development clinical study program(s), from phase 1 through registration globally. - Primary point of contact for medical inquiries from sites, CRO and site monitors; answer or triage questions as appropriate integration of clinical/regulatory strategy into global product development strategy. - Primary liaison for internal Clinical Operations for site selection, site start-up activities, study management and closeout activities, etc.

Senior Director, International Medical Affairs Zug MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY This position reports to the Head of International Medical Affairs and is responsible of conceiving, planning and implementing the medical affairs tactics in the assigned therapeutic area. He/she will also contribute to establish the international medical strategy through cross functional interaction, in alignment with medical leads in the Countries and sitting in the Global medical Affairs Team (GMAT). He/she will lead the scientific initiatives within the European countries that Mirum directly supports and with our distributor partners. JOB FUNCTIONS/RESPONSIBILITIES - Coordinate the international medical plan development and execution for the assigned area, ensuring consistency with the country level plans and with the GMAT. - Lead the development of scientific symposia at congresses and other medical education initiatives - Plan and execute EU congress related medical activities: KOL engagement, advocacy engagement, scientific booths in alignment with product strategy - Organize and support scientific advisory boards - Present scientific data at key congresses and provide input/feedback into final congress presentations. - Represent Int Med Affairs in EU PAG engagement/ advocacy; collaborate with and support Int PAG strategy and develop/ execute related tactics -

Senior Manager, Bioanalytical Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Senior Manager, Bioanalytical will be responsible for all aspects of bioanalytical in the development and approval of Mirum rare disease assets. As a key member of the small Clinical Pharmacology & Nonclinical Sciences group, the individual will represent these multiple functions on multidisciplinary drug development teams to define the strategy and oversee the execution of required studies/analyses through CROs to achieve team goals. JOB FUNCTIONS/RESPONSIBILITIES - Serves as the bioanalytical lead on project and study teams, providing subject matter expertise on clinical development programs - Leads the design and is responsible for the execution of nonclinical and clinical bioanalytical studies for all Mirum assets - Manages collaborations with CROs and consultants, providing technical oversight as needed and ensuring timely and quality deliverables to fulfill project goals - Leads the completion of the relevant sections of IND, NDA, MAA, other regulatory documents and works closely with Regulatory to support clinical document submission - Provides CROs with technical oversight as needed and ensures that assay development, validations, sample analysis, and data transfers occur at CROs and in-house to meet project goals QUALIFICATIONS Education/Experience:

Director, Publications Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Director of Publications manages external publication vendors as well as edits medically relevant scientific presentations (i.e., clinical, scientific, and health economics, abstracts, posters, and oral presentations) to fulfill scientific and medical objectives, in accordance with authors' direction and in adherence to Publication Policy Procedures and ICMJE and GPP3 guidelines. Assists with the creation of other scientific documents (e.g., medical science liaison [MSL] training slide decks, training tools, and FAQs). Communicates effectively with external authors and internal stakeholders and presents project updates to Sr. Director VLX GMAT Team, Executive Director, Publications, Executive Director, Medical Affairs, Senior Vice President of Medical Affairs, and Mirum Senior Leadership. JOB FUNCTIONS/RESPONSIBILITIES Key Responsibilities: - Understand scientific and medical content in given areas of the company. - Review and edit scientific content for oral and poster presentations at congresses. - Manage publications vendor and work closely with key internal and external stakeholders. - Implement the publication management system (Datavision). - Development of scientific training tactics (eg, internal training MSL decks, tools, FAQs). - Engage internal and external subject matter experts, when appropriate, for participation in scientific communication tactics

Senior Director, Intellectual Property Attorney Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY We are seeking an experienced Senior Director, Intellectual Property to lead our intellectual property (IP) strategy in support of our mission to develop and commercialize transformative therapies for patients with rare diseases. This role reports to the Chief Legal Officer, requires a balance of strategic acumen and hands-on execution and will be responsible for shaping and executing a comprehensive global IP program across our clinical and commercial programs. As a senior legal leader in a dynamic, high-growth biopharmaceutical organization (~350 employees worldwide), you will partner closely with internal teams and outside counsel to maximize the value of our programs while mitigating risk. PRIMARY RESPONSIBILITIES IP Strategy & Portfolio Management - In partnership with the Chief Legal Officer and outside intellectual property counsel, develop and oversee a global IP strategy for the company's patents, trademarks and trade secrets. - Lead and oversee the drafting, filing, prosecution, and maintenance of a worldwide patent portfolio. - Provide guidance on patent term extensions and regulatory exclusivities. - Deliver freedom-to-operate (FTO), patent validity, and infringement analyses to inform decision-making across development and commercial programs. -

Director, Medical Writing Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY Director, Medical Writing works closely with stakeholders in Clinical Development, Clinical Operations, Biostatistics, and other functional areas and manages medical writing service providers to develop Regulatory documents, including but not limited to clinical study protocols and clinical protocol amendments, clinical study reports, patient narratives, clinical development plans, IND submissions, integrated summary reports, NDA/MAA and eCTD submissions, and Investigator Brochures, etc. JOB FUNCTIONS/RESPONSIBILITIES - Participate in and oversee vendors for the writing, editing, and confirmation of the scientific and medical accuracy of clinical and regulatory documents. - Work collaboratively to incorporate/adjudicate comments from internal and external stakeholders through document development to produce final high-quality deliverables. - Interact with internal stakeholders and with external service providers to ensure the timely development, review, and publication of documents. - Critically analyze complex data and information and collaborate with clinical, medical, and biostatistics/data science teams on data analysis, description, and presentation. - Coordinate the development of the documents named above and others as assigned by the Head of Medical Writing. - Ensure quality control of documents as well as formatting finalization. - Provide support in development of

Associate Director, GCP QA Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Associate Director of GCP/GVP/GLP-QA is responsible for supporting Mirum's clinical study programs as the GCP-QA representative on the study management team; managing activities involving GCP quality assurance and compliance with applicable regulatory requirements; development and implementation of policies and procedures to ensure quality standards in compliance with relevant regulatory and quality guidelines. Additionally, this position will support GVP and GLP QA operational activities to ensure data integrity and meeting regulatory expectations and industry standards. This position requires experience with global contract research organizations (CROs) and GCP Vendors as well as knowledge of global GCP regulations. JOB FUNCTIONS/RESPONSIBILITIES - Achieve established timelines for deliverables. - QA Representative for assigned Mirum's Program's Clinical Study Management Teams. - Manage/Support BIMO inspection readiness activities - Support GCP/GCLP/GVP internal audits. - Provide quality oversite for the GCP/GVP/GLP vendor activities, including internal/external deviations, CAPAs, change controls, and KPIs/KQIs. - Support GCP, GCLP and GVP Vendor Management/Audit Program. Ad hoc audits may be requested. - Assist with planning and supporting Clinical Site Management/Audit Program. Ad hoc site audits may be requested. - Assist with and support regulatory

Vice President, Clinical Pharmacology Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY Executive leader responsible for Clinical Pharmacology strategy and its integration across all development programs at Mirum, with potential scope to oversee broader pharmacology functions, including nonclinical pharmacology, depending on candidate experience. JOB FUNCTIONS/RESPONSIBILITIES - Lead the design and execution of a clinical pharmacology development plan for all Mirum assets - Set the clinical pharmacology strategy across the portfolio aligned with corporate and regulatory objectives - Develop resource plans via employees and vendors to enable clinical pharmacology development of Mirum assets - Build and lead the Clinical Pharmacology function, including talent strategy and capability development - Lead and influence cross-functional teams to achieve clinical pharmacology goals - Serve as a key contributor to development governance and decision-making - Continually review and monitor guidance, regulations, and publications in clinical pharmacology development and relevant therapeutic areas - Provide input on clinical safety programs (informed consent, exclusion criteria, pregnancy, etc.) and clinical pharmacology programs (ADME, DDIs, PK/PD, BE, etc.) - Identify and work with expert consultants as needed to fill project needs - Ensure completion of relevant sections of IND, NDA, MAA, and other regulatory

Associate Director, Program Management Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Associate Director, Program Management plays a central role within Mirum by providing program management expertise and ensuring cross-functional planning and execution. The program manager partners with the Program Lead and functional leads to develop and manage the integrated product plan, develop timelines, and ensure adherence to the budget for one of our pipeline programs. JOB FUNCTIONS/RESPONSIBILITIES - Support the Program Lead with the development, communication, and timely execution of the program strategy - Organize and drive effective and action-oriented program team meetings by preparing and distributing agendas/minutes, identifying and tracking decisions and action items to resolution, and escalating areas of concern as needed - Partner with the Program Lead to facilitate effective cross-functional decision making with transparent communication and clear escalation pathways - Facilitate identification of risks which could impact the program's strategic goals; propose and implement plans to mitigate risks or develop contingencies - Develop and maintain integrated program timelines in conjunction with functional leads - Identify and communicate program priorities, interdependencies, and critical path activities to all stakeholders to allow long term planning, including resource allocation - Organize

Associate Director, Patient Services Operations Charlotte, NC MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Associate Director, Patient Services Operations will manage the day-to-day hub operations for the Mirum in-house Mirum Access Plus (MAP) program, supporting Mirum's product portfolio and continued expansion over time. The Associate Director will support the Director, Patient Services Operations, leading all day-to-day operations of their team. Duties will include overseeing ensuring all KPIs are met or exceeded, anticipating/identifying/resolving potential operational challenges, overseeing accurate and timely reporting of results, monitoring program budgets, and ensuring all legal, regulatory and pharmacovigilance requirements are being met. The Associate Director will also interact regularly with brand teams and other internal functional areas including finance, legal, safety, quality, training and others as needed. JOB FUNCTIONS/RESPONSIBILITIES - Team Leadership: Lead a team responsible for specialty pharmacy access, reimbursement, and affordability activities. This includes, but not limited to supporting day-to-day activities, managing work queues, delegating assignments, developing team skills, establishing baseline goals, and motivating the team. Develop plans for team members within the team to support in achieving their desired goals. Ensure team goals are aligned with overall organizational strategies. - Program Operations: Ensure that all program

Senior Director, International FP&A Zug MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY Reporting to the Executive Director of FP&A (based in US), the Senior Director, FP&A - International will lead and own the financial planning and analysis function for Mirum's International Commercial Operations. Based in Zug, this role serves as the primary finance partner to International leadership, with full accountability for financial performance, planning, and strategic decision support across Europe and expanding global markets. This individual will play a critical role in building and scaling the international finance capability to support the commercialization of LIVMARLI and future pipeline assets. As a core member of the International leadership team, the role will drive financial visibility, inform strategic decisions, and ensure alignment between regional execution and global corporate objectives. This position combines strategic leadership with hands-on execution in a dynamic, growth-stage biotech environment and requires close collaboration with Commercial, Market Access, Supply Chain, R&D, Legal, Compliance, HR, and global Finance teams. JOB FUNCTIONS/RESPONSIBILITIES International Commercial Finance Leadership - Own and lead FP&A for International Commercial Operations, with full accountability for regional P&L performance - Serve as the primary finance partner to International leadership, influencing strategy, investment

Senior Director, CMC Project Management Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY We are looking for a Senior Director of CMC Project Management who is upbeat, organized, self-motivated, collaborative, detail-oriented, and has a strong technical background and knowledge base. The person filling this player/coach role will partner with the Head of Tech Ops, Biologics to provide strategic and operational leadership to the brelovitug CMC program, overseeing the development and implementation of integrated CMC plans from PPQ campaigns through global regulatory submission, approval, commercial launch, and lifecycle management activities. This role requires being able to prioritize to meet both short-term and long-term goals. This is a fantastic opportunity to make an impact, wear many hats, and be a part of an exciting growing biotech company. This position is located in Foster City. JOB FUNCTIONS/RESPONSIBILITIES - Manage program CMC budgets and related contracts, partnering with internal Finance and Contract functions. - Serve as the primary business lead for external partners, ensuring technical transfers, manufacturing campaigns, testing, and other externally sourced activities stay on schedule and within budget. - Maintain dashboards and reporting mechanisms for program status, risks, decisions, and critical path updates for team

Regional Account Manager, Southern California US Remote MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Regional Account Manager, Southern California (RAM) is a key field position and will have the opportunity to run their own business within their assigned region. Reporting to the Area Business Director, West, this individual will possess experience in business ownership, leadership, analytics, and the implementation of innovative solutions. The RAM will formulate an effective regional strategy focusing on Geneticist, Endocrinology, and Metabolic Specialist as their core customers. They will be tasked with establishing short- and long-term business tactics. It will be the responsibility of the RAM to identify key priorities within territories and create and implement business plan that is organizationally approved and fully compliant with all laws. The RAM will be accountable for improving diagnosis rates of all on label indications within their region, growing sales, and effectively partnering across the organization to ensure all goals are met. The successful RAM will have courage, talent and dedication to seek solutions that can make a meaningful impact within territory or broader team. The ideal candidates are detail orientated, self-structured in their approach to their work, with the ability to

Senior Director, US Market Access Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY Mirum Pharmaceuticals is a rare disease company with a growing portfolio of innovative therapies and a robust pipeline, Mirum is committed to improving the lives of patients who often face limited treatment options and complex care journeys. We operate with a deep sense of purpose and urgency-grounded in our values: Care. Have Fun. Be Real. Get it Done. As we continue to scale, market access plays a critical role in ensuring that innovation translates into real-world patient access. The Senior Director of U.S. Market Access will: - Shape and elevate U.S. market access strategy to drive optimal coverage, pricing, and patient access across the existing portfolio and future assets. - Lead critical access decisions end-to-end-owning pricing strategy, payer positioning, and execution with a high degree of autonomy. - Challenge the status quo by introducing differentiated, insight-driven approaches rooted in real-world payer dynamics and behavior. This role is highly cross-functional and enterprise-facing, partnering across Commercial, Medical, Patient Services (HUB), Government Pricing, Legal/Compliance, and Supply Chain to shape and deliver meaningful access strategies. The ideal candidate blends strategic vision with operational experience,

Senior Director, Regulatory Affairs CMC Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSTION SUMMARY The Senior Director, Regulatory Affairs CMC is a position requiring a strong leader who will provide strategic and operational leadership, and who will ensure the effectiveness of the Regulatory Affairs CMC team within the Regulatory Affairs department and across the organization. The position will be responsible for all CMC-related submissions: strategic planning, execution, and ensuring quality and accurate supporting documents are submitted within the agreed upon timelines. The ideal candidate will need to be able to accurately interpret and discuss CMC data within cross-functional teams and with Health Authorities. JOB FUNCTIONS/RESPONSIBILITIES - Oversees the development and implementation of all regulatory CMC strategies to support market applications, post-marketing CMC commitments, and global development programs across Mirum portfolio. - Directly leads the regulatory CMC strategy for assigned projects. - Responsible for ensuring the appropriate execution of all regulatory CMC strategies. - Actively seeks out knowledge of overall corporate planning, business objectives, and current regulatory requirements to develop regulatory positions for assets in Mirum portfolio, and incorporates this knowledge into submission planning. - Ensures the effectiveness of the Regulatory CMC team in developing

Associate Director, Regulatory Affairs Advertising and Promotion Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Associate Director, Regulatory Affairs Advertising and Promotion provides regulatory guidance on commercial regulatory activities to enable the business to meet its commercial needs in a compliant manner. This position will provide regulatory guidance as a member of the Medical, Legal and Regulatory (MLR). This role is accountable for helping develop strategies and timelines, and managing internal team discussions to support preparation of advertising and promotional materials for regulatory submissions. This role will report to the Director, Global Regulatory Affairs Advertising and Promotion. JOB FUNCTIONS/RESPONSIBILITIES - Responsible for providing commercial regulatory oversight for assigned programs. - Manage and author commercial regulatory submissions, working closely with the Publishing vendor to ensure timely publishing and submission of promotional materials to the Office of Prescription Drug Promotion (OPDP). - Provide regulatory guidance on new concepts and new campaigns. - Maintain a continued awareness and understanding of FDA regulations, guidance documents, and enforcement actions with regards to advertising and promotion of pharmaceutical products. Help monitor enforcement trends and provide timely advice to the team. - Recognized as a resource for commercial regulatory

Regional Account Manager, Carolinas – GEM US Remote MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Regional Account Manager, Carolinas (RAM) is a key field position and will have the opportunity to run their own business within their assigned region. Reporting to the Area Business Director, East, this individual will possess experience in business ownership, leadership, analytics, and the implementation of innovative solutions. The RAM will formulate an effective regional strategy focusing on Geneticist, Endocrinology, and Metabolic Specialist as their core customers. They will be tasked with establishing short- and long-term business tactics. It will be the responsibility of the RAM to identify key priorities within territories and create and implement business plan that is organizationally approved and fully compliant with all laws. The RAM will be accountable for improving diagnosis rates of all on label indications within their region, growing sales, and effectively partnering across the organization to ensure all goals are met. The successful RAM will have courage, talent and dedication to seek solutions that can make a meaningful impact within territory or broader team. The ideal candidates are detail orientated, self-structured in their approach to their work, with the ability to

Regional Account Manager, Keystone – GEM US Remote MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Regional Account Manager, Keystone (RAM) is a key field position and will have the opportunity to run their own business within their assigned region. Reporting to the Area Business Director, East, this individual will possess experience in business ownership, leadership, analytics, and the implementation of innovative solutions. The RAM will formulate an effective regional strategy focusing on Geneticist, Endocrinology, and Metabolic Specialist as their core customers. They will be tasked with establishing short- and long-term business tactics. It will be the responsibility of the RAM to identify key priorities within territories and create and implement business plan that is organizationally approved and fully compliant with all laws. The RAM will be accountable for improving diagnosis rates of all on label indications within their region, growing sales, and effectively partnering across the organization to ensure all goals are met. The successful RAM will have courage, talent and dedication to seek solutions that can make a meaningful impact within territory or broader team. The ideal candidates are detail orientated, self-structured in their approach to their work, with the ability to

Regional Account Manager, South Central – GEM US Remote MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Regional Account Manager, South Central (RAM) is a key field position and will have the opportunity to run their own business within their assigned region. Reporting to the Area Business Director, West, this individual will possess experience in business ownership, leadership, analytics, and the implementation of innovative solutions. The RAM will formulate an effective regional strategy focusing on Geneticist, Endocrinology, and Metabolic Specialist as their core customers. They will be tasked with establishing short- and long-term business tactics. It will be the responsibility of the RAM to identify key priorities within territories and create and implement business plan that is organizationally approved and fully compliant with all laws. The RAM will be accountable for improving diagnosis rates of all on label indications within their region, growing sales, and effectively partnering across the organization to ensure all goals are met. The successful RAM will have courage, talent and dedication to seek solutions that can make a meaningful impact within territory or broader team. The ideal candidates are detail orientated, self-structured in their approach to their work, with the

Associate Director, Medical Communications (VLX) Foster City MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we're looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Associate Director/Director, Medical Communications for the volixibat Portfolio Global Medical Affairs Team (GMAT) is a critical team role with a high-level of accountability, reporting to the GMAT Lead. This role will focus on developing and executing GMAT materials and initiatives, including development, approval, and roll-out of Field Medical Materials; creation of content for and execution of Medical Advisory Boards; and creation of content for and execution of Scientific Symposia and other Medical Education initiatives. The Associate Director/Director of Medical Communications will collaborate with external Medical Communications agencies and Medical Education partners to create timely, relevant, accurate, and engaging tools and programs that support Mirum scientific and medical objectives. They will also collaborate in the management of the database of Medical Field tools, including updating, archiving, and tracking of existing materials, and strategic planning and development of new tools based on the needs and objectives of the GMAT. Essential to this role is the ability to effectively communicate and work with internal stakeholders and external thought leaders in a fast-paced environment. JOB FUNCTIONS/RESPONSIBILITIES - Ensuring Medical Affairs initiatives and tactics