Crinetics Pharmaceuticals INC jobs

Senior Director, Clinical Science Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Senior Director, Clinical Science will be working within a multi-disciplinary team and leading a group of Clinical Scientists implementing Endocrine Clinical Development programs. This individual will provide clinical expertise and scientific insights to clinical development activities (phase 1 - 3 studies), including regulatory documents. The incumbent will collaborate with all the groups involved in Clinical Development e.g., Clinical Pharmacology (CP), Clinical Operations, Medical Writing, Biometrics, Pharmacovigilance, Regulatory Affairs, HEOR and Medical Affairs. Essential Job Functions and Responsibilities: These may include but are not limited to: Lead and mentor the Clinical Scientist team (including consultants), reviewing their work and supporting their professional development. Serve as a scientific liaison between clinical research

Senior Clinical Scientist Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Senior Clinical Scientist will be working within a multi-disciplinary team focusing on a Clinical Development Program. This individual will provide clinical expertise and scientific insights to help monitor, track, and analyze subjects' data in phase 1 - 3 studies. The incumbent will work closely with the Medical Lead and will collaborate with all the groups involved in Clinical Development e.g., Pharmacokinetics (DMPK), Clinical operations, Biometrics, Pharmacovigilance, and Medical Affairs. Essential Job Functions and Responsibilities: These may include but are not limited to: Responsible for monitoring, tracking, and analyzing clinical trials subjects' data, under the supervision of the Clinical Medical Lead. This involves collaborating with investigators, CRO medical monitors, Clinical Operations and

Manager, Centralized Start Up Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Manager, Centralized Start-up will support centralized study and site activation activities with a focus on leading the detailed review, negotiation, and acceptance of informed consent documentation for Crinetics clinical studies that is compliant with ICH GCP, Crinetics internal processes, and local regulations. Incumbent will also support and/or coordinate study-start up activities such as feasibility, site identification, essential document collection and tracking, and site activation. The Manager will also support or develop processes related to informed consent review and study start-up activities. Essential Job Functions and Responsibilities: These may include but are not limited to: Lead country and site-level review, negotiation, and acceptance of new and updated informed consent documentation

Manager, Clinical Business Operations Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Manager, CBO will support the AD, CBO with the internal growth of the newly formed CBO pillar under the Outsourcing and Vendor Governance (OVG) department. This role will primarily develop and negotiate US site budgets for Crinetics' late phase clinical trials. Strong negotiation and cross-functional relationship skills are key to this position. This role will also provide input into developing processes, various trackers, and metrics reporting for CBO. Essential Job Functions and Responsibilities: These may include but are not limited to: Develop, negotiate and execute site budgets and ensure consistency among sites with multiple Crinetics' studies Close collaboration with global CRO partners on the site budget template development and

Director, Patient Marketing Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Director, Patient Marketing, will be instrumental in crafting and implementing strategies and tactics tailored to the rare disease community. Your responsibilities will include spearheading a range of initiatives, from near-term execution to developing new capabilities for mid-to-long-term brand success. This encompasses managing educational initiatives, cultivating relationships with key opinion leaders, and ensuring all marketing initiatives for patients and healthcare professionals adhere to company compliance standards. Essential Job Functions and Responsibilities: These may include but are not limited to: Develop comprehensive patient-centric strategies across multiple disease states including understanding the patient journey, identifying unmet needs, developing innovative solutions, and executing programs to meet those needs. Lead patient ambassador programs to include

Director, Program Management Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Director, Program Management is a leadership role responsible for driving cross-functional execution and providing strategic operational leadership for Crinetics' drug development programs. As a senior member of the Program and Portfolio Management organization, this role serves as a strategic partner to the Program Global Product Leader (GPL), translating program strategy into integrated, executable plans and enabling timely, high-quality decision-making across a complex matrix. The Director owns the integrated program plan and critical path across one or more programs, leads program operating rhythms and governance forums, and proactively identifies risks, interdependencies, and tradeoffs across timeline, scope, and resourcing. The role provides clear, executive-ready visibility into program status, decisions, and delivery implications

Senior Director, Intellectual Property Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Senior Director, Intellectual Property will be responsible for independently developing and implementing strategies to protect Crinetics' intellectual property, primarily its patent assets. This position will also play a critical role in the management of patent prosecution in-house and by outside counsel. The Senior Director, Intellectual Property will serve a variety of business partners and must have the ability to communicate complex legal advice to colleagues with a wide range of scientific backgrounds at all levels of the organization. Work can be based at Crinetics' headquarters in San Diego or remote. Essential Job Functions and Responsibilities: These may include but are not limited to: Identify commercially valuable IP in collaboration

Director, Quality Engineering Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. POSITION SUMMARY: The Director of Quality Engineering will lead the development, integration, and execution of strategic GMP quality initiatives within a fast-paced, highly regulated pharmaceutical environment. This key leadership role is responsible for embedding a proactive, risk-based mindset across global operations to ensure product quality, patient safety, and sustained regulatory compliance. As the enterprise lead for Quality Risk Management (QRM) and Continuous Improvement (CI), the Director will oversee the design and implementation of scalable, risk-based quality frameworks that anticipate and mitigate compliance and supply chain risks. Responsibilities include strengthening inspection readiness, reinforcing data integrity, and driving a robust Corrective and Preventive Action (CAPA) culture across the organization. The role will also lead initiatives to

Manager, Trial Disclosure, Medical Writing Operations Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Manager of Medical Writing Operations - Trial Disclosure role is responsible for clinical trial transparency and disclosure activities, including initial trial postings, results postings, document redaction, and plain language summary development. The role is responsible for ensuring accurate and compliant public release of clinical trial information while working in close collaboration with cross-functional teams. This role is also responsible for redacted documentation in accordance with company confidential information (CCI) and the General Data Protection Regulation. Essential Job Functions and Responsibilities: These may include but are not limited to: Ensure company compliance with clinical trial transparency laws and requirements by applying expert knowledge of key regulatory frameworks, including

Director, Global Product Leader Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: This position will lead several early or one late-stage development programs and contribute to portfolio strategy for other programs within a growing preclinical and clinical stage pipeline covering endocrinology and endocrine related tumors. The Director, Global Product Leader is responsible for the strategic leadership of a Global Product Team, overseeing strategic planning, decision making, and resource/budget management and prioritization across development, regulatory, CMC, operations, and business functions to ensure rapid, efficient, and successful progression of the program(s). This role will be responsible for the full lifecycle management of their product and ensure that strategic plans and goals are met. The Global Product Leader will ensure cross-functional and organizational readiness for regulatory

Senior Medical Affairs Operations Manager Remote Crinetics is a pharmaceutical company based in San Diego, California that develops much-needed therapies for people with rare endocrine diseases. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and robust pipeline across preclinical and clinical development . We are driven by science with a patient-centric and team-oriented culture . This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Come join our team as we transform the lives of others. Position Summary: The Senior Medical Affairs Operations Manager is responsible for managing the execution of medical affairs operations, investigator initiated clinical studies, post-marketing clinical studies and post-trial access programs. The incumbent oversees the review, monitoring, and adherence to clinical protocols, taking ownership of key projects and working independently. The Senior Manager, Medical Affairs Operations, will interact internally and externally with members of the cross-functional study team and may supervise more junior managers and/or assistants as required. Essential Job Functions and Responsibilities: These may include but are not limited to: Provide oversight of clinical affairs programs across all functional areas of the drug development process, including post-trial access programs coordinating the continued provision of investigational product to participants, in accordance with regional regulations. Provide

Senior Director, Clinical Pharmacology Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Senior Director, Clinical Pharmacology will be a key member of the development team, developing clinical pharmacology strategy suitable for target product profile (TPP) and clinical development plan (CDP), leading the design, execution, interpretation and reporting of Phase 1 clinical pharmacology studies, and serve as clinical pharmacology lead on studies and project teams. The work will support projects at various stages of development thereby allowing the selected candidate to play an active role in our drug discovery and development efforts to advance small molecule therapeutics for rare endocrine disorders and endocrine-related cancers. Essential Job Functions and Responsibilities: These may include but are not limited to: Develop clinical pharmacology strategy and related

Director, Quality Systems, Project Management, QRM, RS US California Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: We are seeking a highly skilled Director of Quality Systems with a focus on Project Management, Quality Risk Management (QRM), and Regulatory Surveillance to join our Quality team. This role will be instrumental in managing QA projects, implementing risk management strategies and tools, and ensuring adherence to cGMP regulations and global pharmaceutical quality standards. The ideal candidate brings cross-functional leadership, regulatory knowledge, and strong analytical capabilities to support our commitment to patient safety and product integrity. This role is also responsible for developing collaborative and productive partnerships internally, as well as externally with Global sites and strategic partners. Essential Job Functions and Responsibilities: These may include but

Senior Manager, Supply Chain Quality Assurance Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Senior Manager, Supply Chain Quality is primarily responsible for management and oversight of quality processes overseeing packaging / labeling, distribution, QP oversight for clinical and commercial supplies, and supportive operations in compliance with Good Manufacturing / Distribution Processes. Essential Job Functions and Responsibilities: These may include but are not limited to: Perform batch record review, and disposition related activities for Clinical and Commercial Supplies Coordinate and manage Quality Events (Deviations, CAPAs) with CMOs and escalate them to QA management Oversee QA Packaging / Labeling Operations and distribution for Crinetics products Review and approve labeling artwork for clinical and commercial product Partner with Clinical Trial Supply organization to develop

Senior Director, Global Privacy Remote Position Summary: Crinetics is seeking a highly experienced and strategic Senior Director, Global Privacy to provide enterprise-level leadership of the company's global privacy and data protection. Reporting to the VP, Global Compliance, this role serves as a senior legal and strategic advisor responsible for advancing privacy governance and strategy while managing complex privacy risk across clinical development, research pharmacovigilance, and commercial operations. This position plays a critical role in scaling and maturing the privacy function, including oversight of policies, controls, third-party risk, incident response, and regulatory change management. The role requires significant independent judgment, cross-functional leadership, and the ability to influence and guide senior leaders through complex privacy, cybersecurity, and data-use issues in a public-company pharmaceutical environment. Essential Job Functions and Responsibilities: These may include but are not limited to: Lead the design, implementation, and ongoing enhancement of Crinetics' global privacy and data-protection program, including the design, implementation, and ongoing oversight of policies, standards, procedures, and controls aligned with U.S. and international privacy laws and industry best practices. Establish and chair enterprise privacy and data-governance forums, defining decision rights, escalation pathways, and accountability across functions. Provide regular executive-level reporting on privacy risk posture, program effectiveness, and emerging regulatory developments. Serve as the company's senior legal authority on privacy, data protection, and data-use governance, advising executives and cross-functional leaders on risk-based, compliant approaches to business initiatives. Translate complex legal requirements into practical operating guidance that supports innovation, patient trust, and responsible data use. Provide senior-level oversight

Senior Shipping and Receiving Clerk San Diego, CA Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Senior Shipping and Receiving Clerk is a detail-oriented and experienced operations professional who works effectively in a fast-paced, collaborative, and regulated environment. This role is responsible for executing daily shipping and receiving operations, coordinating inbound and outbound logistics, ensuring accurate documentation, and maintaining a safe and organized work environment. The position requires prior experience in a pharmaceutical, biotechnology, life sciences, or similarly regulated industry. The Senior Shipping and Receiving Clerk partners closely with Facilities and Operations teams, vendors, and logistics providers to support compliant, efficient, and cost-effective material movement while adhering to all applicable safety and regulatory requirements. Essential Job Functions and Responsibilities: These may include but

Director, Omnichannel Marketing Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Director, Omnichannel Marketing will play a critical role in designing, executing, and optimizing integrated omnichannel strategies that engage patients, healthcare professionals, and other key stakeholders across the customer journey. This role will lead the development of cohesive, data-driven experiences across digital, non-personal, and personal channels, ensuring consistent messaging, optimal channel mix, and measurable impact. The Director will be responsible for building and scaling omnichannel capabilities, partnering closely with brand, analytics, IT, commercial operations, and agency partners to drive short-term execution while establishing sustainable mid- to long-term omnichannel excellence. This role ensures all initiatives are executed in compliance with company policies and applicable regulatory requirements. Essential Job Functions and Responsibilities: These may

Associate Director, Clinical Pharmacology Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Associate Director, Clinical Pharmacology will be responsible for developing clinical pharmacology strategy suitable for target product profile (TPP) and clinical development plan (CDP), leading the design, execution, interpretation, and reporting of Phase 1 clinical pharmacology studies, and serve as clinical pharmacology lead on studies and project teams. The work will support projects at various stages of development thereby allowing the selected candidate to play an active role in our drug discovery and development efforts to advance therapeutics for rare endocrine disorders and endocrine-related cancers. This is a unique opportunity to work with a proven and well-funded drug discovery and development team in a small company environment in the heart of

Senior Contracts Manager Remote Position Summary: The Senior Contracts Manager is responsible for comprehensive support of the organization's commercial and general and administrative (G&A) contracting program, including the review, drafting, negotiation, and administration of a broad range of commercial and operational agreements. These include master services agreements, confidentiality agreements, consulting agreements, statements of work, and related contracts. In addition to contract execution, this role contributes to the development and ongoing maturation of contracting processes, templates, and workflows, partnering closely with Commercial, Medical Affairs, Finance, Procurement, and other stakeholders to ensure contracts strategically support the business needs. Work can be based at Crinetics' headquarters in San Diego or remote. Essential Job Functions and Responsibilities: These may include but are not limited to: Collaborate with Compliance and other internal stakeholders to implement and manage documentation and administrative processes for review and approval of Commercial, Legal, Compliance and Medical Affairs activities under the direction of Executive Director & Associate General Counsel, Commercial Legal. Support Commercial and Medical Affairs initiatives through ad hoc legal research, cross-functional collaboration, and other related responsibilities, as assigned. Draft, review, negotiate, and execute a broad range of contracts supporting diverse business transactions. Lead contract negotiations, including reviewing and coordinating stakeholder input on redlines to ensure appropriate review and approval by business, Finance, Compliance, IP, and other relevant partners. Ensure contractual terms and conditions are consistent with Crinetics policies, standards, and established guidance. Exercise sound judgment to identify contract issues, decisions, or other matters impacting agreements that require escalation, and

Senior Director, Pharmaceutical Strategy and Development Leader San Diego, CA Crinetics is a pharmaceutical company based in San Diego, California that develops much-needed therapies for people with rare endocrine diseases. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and robust pipeline across preclinical and clinical development. We are driven by science with a patient-centric and team-oriented culture. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Come join our team as we transform the lives of others. Position Summary: The Senior Director, Pharmaceutical Development Team Leader (PDTL) is responsible for developing and leading the execution of comprehensive, compound-specific Technical Operations strategies to meet the global project team's (GPT) needs. This role provides leadership to interdisciplinary teams, managing multiple assets through various stages of development, and collaborates with various functional areas to achieve optimal development and business results. Essential Job Functions and Responsibilities: These may include but are not limited to: Develop, refine, update, and oversee Technical Operations project plans from multiple inputs, with emphasis on the alignment of these plans with strategic objectives, the decomposition of major objectives into discrete WBS-level work packages, the mapping of internal and cross-functional interdependencies, and the management of project risks. Perform detailed

Senior Medical Director, Asset Lead – Oncology (Neuroendocrine Tumors / Carcinoid Syndrome) Remote Crinetics is a pharmaceutical company based in San Diego, California that develops much-needed therapies for people with rare endocrine diseases. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and robust pipeline across preclinical and clinical development. We are driven by science with a patient-centric and team-oriented culture. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Come join our team as we transform the lives of others. POSITION SUMMARY: Crinetics is seeking an experienced oncology Medical Affairs leader to serve as Senior Medical Director, Asset Lead - Oncology (Neuroendocrine Tumors / Carcinoid Syndrome), reporting to the Executive Director, Medical Affairs. This role will provide Medical Affairs leadership for a complex oncology program within the Neuroendocrine Tumor (NET) landscape, requiring deep expertise in oncology clinical development, competitive data interpretation, and cross functional medical strategy. This individual will be responsible for shaping and executing Medical Affairs strategy across evidence generation, scientific exchange, and KOL engagement, ensuring alignment with Clinical Development, Regulatory, Commercial, Market Access, Compliance, and Legal functions. The role demands strong scientific credibility in oncology, the ability to interpret and translate complex oncology data, and comfort

Associate Director, Outsourcing & Vendor Governance & Supplier Management (CMC) San Diego, CA Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Associate Director, Outsourcing & Vendor Governance (OVG) & Supplier Management is responsible for the strategic oversight, governance, and performance management of external suppliers supporting the Technical Operations / CMC organization. This role manages a broad and complex network of external partners across development, manufacturing, testing, and supply to ensure reliable, compliant, and cost-effective execution of CMC programs. This position is critical to enabling program success by ensuring external suppliers are effectively selected, governed, and integrated into the company's Technical Operations strategy. The Associate Director serves as a key interface between CMC, Quality, Supply Chain, Finance, and Procurement, and brings deep experience

Associate Director, Quality Assurance GCP Remote Crinetics is a pharmaceutical company based in San Diego, California that develops much-needed therapies for people with rare endocrine diseases. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and robust pipeline across preclinical and clinical development. We are driven by science with a patient-centric and team-oriented culture. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully integrated endocrine company from discovery to patients. Come join our team as we transform the lives of others. Position Summary: The Associate Director, Quality Assurance GCP supports the Good Clinical Practice (GCP) Quality Assurance (QA) function and performs day-to-day GCP QA operations. She/he will execute and/or ensure proper oversight of GCP QA activities, perform external and internal audits, support clinical phase 1 to phase 4 study team activities, review documents, support regulatory inspections, and enhance GCP QA infrastructure development. In alignment with updated ICH E6(R3) expectations, the Associate Director emphasizes flexible, proportionate, and risk-based quality oversight, maintains inspection readiness, and leads proactive, data-driven quality management via continuous identification and mitigation of quality risks. Essential Job Functions and Responsibilities: These may include but are not limited to: Manage or perform clinical site, internal, TMF, GCP, and GLP vendor audits. Generate and/or review GCP and

Associate Director, Regulatory Affairs CMC Remote Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: The Associate Director, Regulatory Affairs CMC will be responsible for supporting regulatory strategy implementation for development programs. Works closely with the Senior Director, Regulatory Affairs CMC to lead and prepare regulatory submissions (authoring, timeline planning, etc.), to support regulatory and clinical objectives. Assists in developing and implementing global regulatory strategies. Establishes and maintains department regulatory processes. The individual is responsible for developing collaborative and productive partnerships internally, as well as externally with contract research organizations, electronic publishing, and other vendors as required. Essential Job Functions and Responsibilities: These may include but are not limited to: Actively participate as a member of Regulatory Affairs teams and on cross-functional product development teams as needed. Contribute to developing and implementing regulatory strategies for global