Associate Principal Computational Biologist, Neuroscience

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About this role

Associate Principal Computational Biologist, Neuroscience New York, New York; Salt Lake City, Utah Your work will change lives. Including your own. The Impact You'll Make As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. As senior computational biologist, you will be supporting a portfolio of partnership preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in neuroscience diseases. You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of neuroscience. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking, and 3) build evidence for patient connectivity to match the targets we are validating and medicines we are creating to the patients who need them. In this role, you will: Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning Evaluate the biological and molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic Synthesize diverse

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