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Sr. Director, Advanced Technologies

Personalis INC - Fremont, CA

Posted Apr 29, 2026

Benefits

Parental leave
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Salary
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401(k) match
Listed Source: EMPLR_CONTRIB_INCOME_AMT. source Last checked Jun 13, 2026.

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Schedule

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Application

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About this role

Sr. Director, Advanced Technologies Fremont, CA Personalis is a genome-scale diagnostics company with a mission to pioneer genome guided medicine. Our priority is to obtain the most accurate genetic data from each sample, and then to draw the most reliable medically-focused conclusions from these. Our tests are based on whole human genome and exome sequencing, conducted in our state-of-the art laboratory. We analyze results utilizing proprietary databases, advanced human reference sequences, and sophisticated algorithms. Personalis is based in Fremont, California. Summary: We are looking for a dynamic and experienced Senior Director of Advanced Technologies to lead a team in scoping, evaluating, and implementing cutting-edge advancements in sequencing, sample preparation and new assay creation. This role will drive innovation in our proprietary technologies, enhancing performance and expanding capabilities. Your contributions will play a key role in shaping the next generation of genomics-based precision medicine products, supporting immuno-oncology, cancer clinical trials, diagnostics, and therapeutics used by pharma, biotech, hospitals, and clinicians. Responsibilities: Develop and execute the advanced technology strategy, ensuring alignment with company objectives and long-term vision. Lead efforts to evaluate and integrate new technologies that expand and improve Personalis products. Participate in forward-looking strategic planning and influence company-wide technology adoption. Identify new initiatives and build consensus across various stakeholder groups with clear success measures. Work closely with bioinformatics teams to design experiments and validate new procedures and analytics. Partner with the operations teams to ensure the smooth adoption of new technologies. Collaborate across functions to troubleshoot issues and implement solutions that

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