Member of the Technical Staff, Pretraining

Benefits

Parental leave

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Non-birth-parent leave

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Family-building benefits

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• Adoption assistance: Not verified
• Surrogacy assistance: Not verified

Mental health support

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Relocation assistance

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Childcare support

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Learning budget

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Verification

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Salary

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401(k) match

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Market context

U.S. role benchmark (BLS OEWS)

$116,543 U.S. median for this role

Projected growth (BLS Employment Projections)

+9.8% - Much faster than average

Matched to SOC 15-1252 - Software Engineering aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function

Engineering From the posting source checked Jun 20, 2026

Seniority

Staff Plus From the posting source checked Jun 20, 2026

Schedule

Shift type

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Weekend work

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Company

Company stage

Seed From the posting source checked Jun 20, 2026

Application

Cover letter

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Assessment

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Deadline

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Where they hire

State eligibility is not yet verified.

About this role

Member of the Technical Staff, Pretraining New York HQ 🗽 Output has built a biological reasoning model that understands biology at the scale and complexity life actually operates. Our model independently learned the principles of molecular interactions, opening up drug treatments that were previously impossible. We're already generating therapies that traditional approaches cannot reach. The hardest problems in both AI and biology are being solved here, and there is room for you to own one. Output is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI x Bio, and backed by top-tier VCs including Y Combinator. You will advance the core architecture and training of Output's foundation model, the system that learns biological reasoning from data. This role spans the full arc from research to trained model: you design architectures, develop training objectives, run pretraining at scale, and evaluate what the model has learned. - You will push forward the architecture and training objectives of our foundation model, designing approaches that are purpose-built for biological reasoning - You will develop methods for the model to learn across multiple biological data modalities simultaneously, building unified representations of molecular biology - You will extend the model's reasoning capabilities across biological phenomena, pushing what it can predict and understand about binding, molecular properties, and biological function - You will own pretraining end-to-end: experiment design, distributed training on multi-GPU clusters, hyperparameter optimization, and iteration - You will design evaluation frameworks that measure whether the model

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