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Principal Clinical Scientist, ECD

Natera, Inc. - US Remote

Posted May 1, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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Childcare support
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Learning budget
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Verification
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Salary
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401(k) match
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Market context

Median wage (BLS OEWS)
$111,944 national median
Projected growth (BLS Employment Projections)
+13.7% - Much faster than average

89% above the BLS national median for data and ml aggregate.

Matched to SOC 15-1252 - Data and ML aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Schedule

Shift type
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Weekend work
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Application

Cover letter
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Assessment
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Deadline
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Where they hire

State eligibility is not yet verified.

About this role

Principal Clinical Scientist, ECD US Remote POSITION SUMMARY: We are seeking a Principal Clinical Scientist to lead execution of key components of clinical development for our early cancer detection (ECD) program. This role is central to leading study execution, clinical data review, study design, and generation of scientific insights across multiple studies. The successful candidate will contribute meaningfully to clinical development strategy through hands-on study leadership, cross-functional execution, and data-driven decision-making. You will serve as a clinical science lead within cross-functional teams-partnering closely with Clinical Operations, Biostatistics, Medical Affairs, and Regulatory to drive study execution, identify risks and opportunities, and contribute to clinical development strategy through study-level leadership and scientific insight. This role is best suited for a clinical scientist who enjoys remaining closely involved in study execution, clinical data review, and cross-functional problem solving while contributing to broader clinical development discussions and strategy. Location: San Carlos, CA or Remote, USA (West Coast or Mountain time zones preferred) PRIMARY RESPONSIBILITIES: Lead Clinical Development & Study Design - Lead substantial aspects of ECD clinical studies or multiple studies - Drive study design, including objectives, endpoints, eligibility criteria, and schedules of assessments - Author and review protocols, ICFs, CRFs, and study documents - Contribute meaningfully to clinical development strategy and study-level decision-making - Contribute to process improvements and development of best practices Drive Data Review & Strategic Insight - Lead medical and clinical data review to ensure data quality and integrity - Analyze complex datasets to identify trends, risks, and opportunities -

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