Director, Clinical Science

Benefits

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About this role

Director, Clinical Science US Remote POSITION SUMMARY: We are seeking a Director, Clinical Science to architect trial strategies and protocol execution for our oncology molecular diagnostics portfolio, with a dedicated focus on signal Studies and pipeline expansion. This clinical leadership role shapes the data validation pipeline for our cell-free DNA (cfDNA) technology, transforming population scale genomic profiles into standard-of-care screening benchmarks. Reporting directly to the Senior Director of Clinical Science, you will lead the strategic alignment and tactical delivery of early and late-stage oncology diagnostics protocols. Operating with an active builder mindset, this position co-develops clinical program strategy and drives collaborative execution across clinical development, clinical operations, biostatistics, and translational data science teams. PRIMARY RESPONSIBILITIES: Trial Strategy and Protocol Architecture - Design robust clinical study concepts, specifying overall design parameters, schedules of assessments, trial objectives, clinical endpoints, and patient eligibility criteria - Lead clinical development activities and protocol design for oncology Signal Studies and portfolio development - Collaborate cross-functionally to author clinical study protocols, informed consent documents, and technical amendments for internal governance review - Deliver technical protocol validation training to internal teams and contract research organizations (CROs), and guide case report form (CRF) layout configurations - Ensure study manuals conform directly to protocol specifications and engage primary clinical investigators during initial trial design phases Data Interrogation and Cross-Functional Alignment - Synthesize protocol requirements from investigators, clinical partners, and regulatory bodies, resolving conflicting operational priorities by anchoring team alignment strictly in data - Partner with cross-functional technical teams to execute

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