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Director, Data Management

MAZE Therapeutics INC - South San Francisco, CA

Posted Feb 20, 2026

Benefits

Parental leave
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Non-birth-parent leave
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Family-building benefits
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Mental health support
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Childcare support
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Learning budget
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Verification
Not verified last checked Jun 13, 2026
Salary
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401(k) match
Listed Source: EMPLR_CONTRIB_INCOME_AMT. source Last checked Jun 13, 2026.

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Schedule

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Weekend work
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Application

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About this role

Director, Data Management South San Francisco, CA The Opportunity Join us at Maze Therapeutics as our Director of Data Management, where you will play a key role in shaping the data strategy that supports our clinical development programs. You'll partner closely with Biostatistics, Statistical Programming, Clinical Operations, and Regulatory Affairs, and oversee external vendors to deliver high-quality, reliable clinical data across our studies. Reporting to the Vice President of Biometrics, you'll provide strategic direction and hands-on leadership for clinical data management activities spanning multiple clinical trials. Your work will ensure timely, compliant, and analysis-ready data that supports regulatory submissions and key program decisions. The Impact You'll Have Lead data management activities across multiple clinical studies and development phases. Shape and implement data management strategies , standards, and best practices. Mentor and support data management team members, fostering growth and knowledge sharing. Serve as a subject matter expert for data management processes, systems, and regulatory expectations. Oversee critical study deliverables including DMPs, CRFs/eCRFs, edit checks, and database locks. Guide accurate, consistent, and timely clinical data collection , cleaning, and reconciliation. Review and approve key study documentation and ensure readiness for analysis and reporting. Drive database lock planning and partner closely with Biostatistics and Medical Writing to support analyses and study reports. Manage CROs and external vendors , ensuring clarity around timelines, quality expectations, and contractual commitments. Support the evaluation , implementation, and optimization of EDC and data management technologies. Collaborate closely with Clinical Operations, Biostatistics, and other partners across the organization.

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