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Sr Principal/ Principal Software Engineer, AI Lab Execution System

Lila Sciences - Cambridge, MA USA; San Francisco, CA USA

Posted Mar 23, 2026

Benefits

Parental leave
Not verified
Non-birth-parent leave
Not verified
Family-building benefits
  • Fertility benefits: Not verified
  • Adoption assistance: Not verified
  • Surrogacy assistance: Not verified
Mental health support
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Relocation assistance
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Childcare support
Not verified
Learning budget
Offered From the posting source checked Jun 20, 2026
Verification
Not verified
Salary
$204K-$348K From the posting source checked Jun 20, 2026
401(k) match
Not verified

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Market context

U.S. role benchmark (BLS OEWS)
$116,543 U.S. median for this role
Projected growth (BLS Employment Projections)
+9.8% - Much faster than average

137% above the BLS role benchmark for software engineering aggregate.

Matched to SOC 15-1252 - Software Engineering aggregate by role bucket.

Source: U.S. Bureau of Labor Statistics, OEWS, May 2024 and Employment Projections, 2024-2034.

Role

Role function
Engineering From the posting source checked Jun 20, 2026
Seniority
Principal From the posting source checked Jun 20, 2026

Schedule

Shift type
Not verified
Weekend work
Not verified

Company

Company stage
Early From the posting source checked Jun 20, 2026
Equity
Offered From the posting source checked Jun 20, 2026

Application

Cover letter
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Assessment
Not verified
Deadline
Not stated

Where they hire

State eligibility is not yet verified.

About this role

Sr Principal/ Principal Software Engineer, AI Lab Execution System Cambridge, MA USA; San Francisco, CA USA Your Impact at LILA We are seeking a Senior Principal or Principal Software Engineer, AI Lab Execution System to join our Scientific System of Record Team and help define and build the next-generation AI-driven scientific platform. In this role, you will serve as a technical leader for systems that connect scientific intent, laboratory execution, data capture, and AI-driven analysis. You will shape the architecture of user interfaces, services, high-performance APIs, databases, and reliability-critical systems that integrate advanced AI frameworks with complex scientific analytics and laboratory workflows. You'll work closely with ML researchers, platform engineers, data engineers, product teams, and scientists to turn complex scientific processes into scalable, elegant software systems. These systems will need to support diverse workloads across structured SQL databases, data lakehouses, workflow engines, and lab execution environments. This is an opportunity to set technical direction for a cutting-edge AI platform with real scientific impact. If you are passionate about building high-leverage systems, mentoring strong engineers, and solving ambiguous problems at the intersection of AI, software, and science, we would love to hear from you. About The Team The Scientific System of Record Team (SSR) builds the memory layer for Lila's operations. It answers two questions: what did we plan to build? and what actually happened? These systems connect scientific intent to physical reality. Together with the data and automation teams, their systems ensure reproducibility and close the Design-Build-Test-Learn (DBTL) loop. What

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