Sr Principal/ Principal Software Engineer, AI Lab Execution System

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About this role

Sr Principal/ Principal Software Engineer, AI Lab Execution System Cambridge, MA USA; San Francisco, CA USA Your Impact at LILA We are seeking a Senior Principal or Principal Software Engineer, AI Lab Execution System to join our Scientific System of Record Team and help define and build the next-generation AI-driven scientific platform. In this role, you will serve as a technical leader for systems that connect scientific intent, laboratory execution, data capture, and AI-driven analysis. You will shape the architecture of user interfaces, services, high-performance APIs, databases, and reliability-critical systems that integrate advanced AI frameworks with complex scientific analytics and laboratory workflows. You'll work closely with ML researchers, platform engineers, data engineers, product teams, and scientists to turn complex scientific processes into scalable, elegant software systems. These systems will need to support diverse workloads across structured SQL databases, data lakehouses, workflow engines, and lab execution environments. This is an opportunity to set technical direction for a cutting-edge AI platform with real scientific impact. If you are passionate about building high-leverage systems, mentoring strong engineers, and solving ambiguous problems at the intersection of AI, software, and science, we would love to hear from you. About The Team The Scientific System of Record Team (SSR) builds the memory layer for Lila's operations. It answers two questions: what did we plan to build? and what actually happened? These systems connect scientific intent to physical reality. Together with the data and automation teams, their systems ensure reproducibility and close the Design-Build-Test-Learn (DBTL) loop. What

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