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Director, Nucleic Acid Delivery

Lila Sciences - Cambridge, MA USA

Posted Mar 11, 2026

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About this role

Director, Nucleic Acid Delivery Cambridge, MA USA Your Impact at LILA The Director of Nucleic Acid Delivery will lead the discovery and engineering of next-generation delivery systems for nucleic acid cargo. This role will drive the design of targeted lipid nanoparticles (tLNPs) and other biological delivery modalities to enable precise delivery of nucleic acids across diverse tissues and cell types. Leveraging the Lila Sciences AI platform and AI Science Factory , this leader will guide an interdisciplinary team of scientists in integrating AI-driven hypothesis generation, robotics-enabled experimentation, and biological insight to accelerate discovery of transformative delivery technologies. The role will focus on the biological targeting and functional delivery, while collaborating closely with formulation scientists responsible for lipid composition and formulation optimization. This position is ideal for a creative scientific leader who believes that AI, automation, and integrated biological systems thinking will fundamentally reshape therapeutic discovery. The successful candidate will bring deep expertise in nucleic acid delivery and a passion for building collaborative teams. What You'll Be Building - Lead and build a high-performing team of senior scientists, scientists, and research associates focused on nucleic acid delivery technology development. - Drive the discovery and engineering of targeted lipid nanoparticle systems for delivery of nucleic acid therapeutics. - Design and evaluate targeting ligands, conjugation strategies, and nanoparticle architectures that enable tissue- and cell-specific delivery. - Develop and implement innovative biological assays and screening platforms to evaluate delivery efficiency, biodistribution, cellular uptake, and functional nucleic acid expression or editing. - Leverage the Lila

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