Sr Engineer-OSD Process (MSAT)
Alkermes - Wilmington, OH, United States
Posted Feb 18, 2026
Benefits
- Parental leave
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- Non-birth-parent leave
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- Family-building benefits
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- Verification
- Not verified last checked Jun 13, 2026
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- 401(k) match
- Listed Source: EMPLR_CONTRIB_INCOME_AMT. source Last checked Jun 13, 2026.
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About this role
Sr Engineer-OSD Process (MSAT) Wilmington, OH, United States Job Summary The Senior Engineer, Oral Solid Dosage (OSD) Manufacturing Science and Technology (MSAT), serves as the process technical authority for critical OSD unit operations, with a primary focus on blending, tablet compression, and low‑shear wet granulation via top‑down spray fluid bed systems. This role is responsible for deep technical ownership of these processes across the product lifecycle, including commercial manufacturing support, technology transfer, troubleshooting, process optimization, and continuous improvement. The position partners closely with Manufacturing, Quality, Engineering, and Process Development to ensure robust, compliant, and capable processes that consistently deliver high‑quality product. The ideal candidate is a recognized subject matter expert (SME) who can translate scientific and engineering principles into practical, shop‑floor solutions while maintaining strong regulatory and GMP alignment. Process Technical Ownership (Primary Focus) Serve as the process SME for OSD unit operations with specific depth and expertise in: Powder blending and blend uniformity control Tablet compression (including tool design considerations, scale effects, and defect mitigation) Low‑shear wet granulation using top‑down spray fluid bed technology (process design, scale‑up, and robustness) Own process understanding, control strategies, and operating envelopes for assigned products and unit operations. Provide real‑time technical decision‑making during manufacturing events, deviations, and atypical process behavior. Manufacturing Support & Troubleshooting Provide hands‑on, floor‑based technical support for commercial OSD manufacturing operations. Lead complex troubleshooting efforts related to: Flow, segregation, and blend uniformity challenges Compression defects (e.g., capping, lamination, sticking, weight variability) Fluid bed granulation issues including spray distribution, granule growth, agglomeration,
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