Employer profile
Alpha-9 Oncology
2 open roles indexed with location, benefit, and apply-link signals where available.
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Senior Director, Clinical Dosimetry & Radiation Sciences
Boston, Massachusetts, USA
unspecified Salary not disclosedSenior Director, Clinical Dosimetry & Radiation Sciences Boston, Massachusetts, USA Your Impact Alpha-9 Oncology is seeking a Medical Physicist to lead clinical dosimetry and quantitative imaging across our radiopharmaceutical clinical programs. Reporting into Clinical Development, this role serves as the internal scientific lead for dosimetry methodology and imaging quantification, ensuring rigor, consistency, and interpretability across multiple active studies. You will define and own how clinical dosimetry is performed at Alpha-9 and ensure it is fully integrated into trial design, dose escalation strategy, and regulatory decision-making. This role operates at the intersection of clinical development, clinical pharmacology, regulatory affairs, and external imaging partners, with direct influence on how quantitative radiopharmaceutical data is translated into clinical decisions. How You'll Contribute - Lead clinical dosimetry strategy across Alpha-9's radiopharmaceutical programs, defining standards for absorbed dose calculation, time-activity modeling, and interpretation across early-phase clinical studies. - Establish and govern quantitative imaging standards for SPECT/CT and PET/CT, including acquisition protocols, reconstruction parameters, QC frameworks, and site qualification criteria. - Serve as the internal authority on dosimetry, translating patient- and program-level dose data into actionable insights that inform dose escalation, safety evaluation, and clinical decision-making. - Integrate dosimetry into clinical trial design and regulatory submissions, including protocols, amendments, investigator brochures, clinical study reports, and IND/CTA documentation. - Partner closely with Clinical Development, Clinical Pharmacology, Biostatistics, and Clinical Operations to ensure dosimetry is embedded in dose selection strategy and study execution. - Manage external imaging and dosimetry vendors and core laboratories, ensuring methodological consistency, data quality, and
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Join the Alpha-9 Talent Network
All Locations
unspecified Salary not disclosedJoin the Alpha-9 Talent Network All Locations Join the Alpha-9 Talent Network At Alpha-9 Oncology, our mission is to advance next-generation radiopharmaceuticals that meaningfully improve outcomes for patients with cancer. We're building a team of thoughtful, driven individuals who are motivated by impact and grounded in scientific excellence, collaboration, and urgency. If you don't see a current role that aligns with your background, we'd still love to connect. By joining our Talent Network, you'll be considered for future opportunities as we continue to grow across Vancouver, Boston, and San Francisco. We regularly review submissions and will reach out if there's a strong match. Company Summary Alpha-9 Oncology is a clinical-stage biotechnology company pioneering radiopharmaceutical innovation for solid tumors. Our proprietary scaffolds, composed of optimized binders, linkers, chelators, and radioisotopes, enable targeted radiation delivery to cancer cells, minimizing harm to surrounding healthy tissue. Focusing on innovative targeting moieties, we develop molecules tailored for precise tumor targeting. Our comprehensive platform integrates imaging and therapeutic studies to ensure effective radiation delivery and improved patient outcomes. With a robust pipeline entering clinical trials and strong support from leading healthcare investors, Alpha-9 is positioned for rapid growth and advancement in cancer therapy. More about Alpha-9 Oncology Alpha-9 Oncology is committed to fostering a diverse and inclusive workplace and is proud to be an Equal Opportunity Employer. We provide employment opportunities to all qualified applicants without regard to race, ethnicity, religion, age, sex, gender identity or expression, sexual orientation, disability, marital status, family status, national origin,