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Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer. This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing. The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts. Summary The Senior MSL is a U.S. field-based role within Medical Affairs, reporting to the Executive Director, Medical Affairs. This role will be a core member of Tango's growing field medical team during a critical phase of development. 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Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. 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For more information, visit https://www.stoketherapeutics.com/ Position Purpose: The Director, Financial Planning & Analysis (R&D) will play a critical role in financial and strategic decision making at the Company, playing a key role in the future growth of the organization. The focus of this position will be to provide overall financial business partnering to the Research & Development (R&D) functions including leading the budgeting, forecasting and long-range planning processes, supporting the monthly and quarterly close process, providing monthly reporting to department leads and the Executive Leadership Team, supporting external collaborations, and performing ad hoc financial analysis. 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