{ "results": [ { "id": "d20a1287567263e05d5ed4cc0eab04a0", "title": "Senior Scientist, Computational Chemistry", "employer_name": "Iambic Therapeutics", "employer_slug": "iambic-therapeutics", "location_text": "San Diego HQ, San Diego, California, United States", "country": "US", "employment_type": "unknown", "remote_status": "unspecified", "remote_status_source": null, "remote_status_enriched_at": null, "days_in_office": null, "timezone_overlap_hours": 6, "salary_min": null, "salary_max": null, "salary_min_source": null, "salary_max_source": null, "salary_currency": "USD", "salary_type": "unknown", "salary_type_source": null, "salary_type_enriched_at": null, "salary_period": null, "base_salary_min": null, "base_salary_max": null, "salary_disclosed": false, "equity_included": false, "equity_included_source": null, "equity_type": [ "none" ], "k401_match": "yes", "match_401k_pct": null, "match_401k_pct_source": null, "k401_match_source_url": null, "k401_match_source_fields": [], "k401_contribution_source_url": null, "k401_contribution_source_fields": [], "profit_sharing": false, "bonus_offered": false, "mental_health_support": null, "childcare_subsidy": null, "fertility_family_building_benefits": null, "adoption_assistance_offered": null, "surrogacy_assistance_offered": null, "student_loan_repayment_offered": null, "learning_budget_offered": null, "relocation_assistance": null, "top_startup_sources": [ "cnbc_disruptor50", "sequoia" ], "posted_at": "2026-04-30T16:40:34.841Z", "apply_url": "https://jobs.ashbyhq.com/iambic-therapeutics/337cfe21-aae6-4d68-ac07-455675ccedcf", "apply_url_verified": false, "ats": "ashby", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "Senior Scientist, Computational Chemistry San Diego HQ, San Diego, California, United States JOB SUMMARY We are seeking a skilled and highly motivated Computational Chemist to join our Computational Sciences group at the Iambic Therapeutics headquarters in San Diego. 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"posted_at": "2026-03-03T18:20:11.678Z", "apply_url": "https://jobs.ashbyhq.com/iambic-therapeutics/07da7cd7-a57b-4cf5-91db-278eb8d99093", "apply_url_verified": false, "ats": "ashby", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "Director, Drug Product Development San Diego HQ, San Diego, California, United States JOB SUMMARY Iambic Therapeutics is seeking a Director , Drug Product Development to lead formulation and process development for small molecule programs from late discovery/IND-enabling through clinical phases, with a clear path to later-stage development, global registrations, and commercialization. This role will set drug product strategy within CMC and drive execution, oversee scale-up, technology transfer, and manufacturing readiness at CDMOs, and ensure high-quality CMC documentation to support global regulatory filings. The successful candidate brings deep subject matter expertise in formulation design and process development to deliver robust, scalable, patient-centric, and cost-effective drug products from early through late phases of clinical development. This role will partner closely with Discovery, Analytical Development, Process Chemistry, Project Management, Quality, Regulatory, Clinical Pharmacology, Clinical Operations, and Supply Chain teams to align development plans, manage risk, and deliver on program timelines. This position will be on-site at our San Diego Headquarters. 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"posted_at": "2026-05-13T21:45:03.902Z", "apply_url": "https://jobs.ashbyhq.com/iambic-therapeutics/416f46b9-e8f1-44e7-8749-590ee26e6d52", "apply_url_verified": false, "ats": "ashby", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "Senior Director/Executive Director, DMPK San Diego HQ, San Diego, California, United States JOB SUMMARY Iambic Therapeutics is seeking an experienced DMPK leader to lead our Drug Metabolism & Pharmacokinetics function. 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This role sits directly alongside ML scientists and emphasizes co-development: helping design, implement, and harden the workflows used to train, evaluate, and apply models on structural (e.g., protein-ligand complexes), affinity, and synthetic data. You will play a key role in turning research code into reliable, reusable systems-without being responsible for core model development. This is a remote position based on the US East Coast. 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You will work in the Software organization and work closely with the ML organization to help drive the Cloud Ops Roadmap, leading and supporting delivery of the roadmap goals for projects across the organization. You will work with teams developing and deploying Iambic's drug discovery platform, Computational Science applications and Machine Learning models. You will also help deliver and support ISO 27001 compliant Cloud Ops processes. This role is preferably Hybrid in Boston, then East Coast, San Diego, or Remote (with workspace support). 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(Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. At Apogee, you can actively contribute to shaping the company culture, take on various roles and responsibilities, and grow professionally. Apogee Therapeutics is a clinical-stage biotechnology company advancing novel biologics with potential for differentiated efficacy and dosing in the largest I&I markets, Apogee's antibody programs are designed to overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. Zumilokibart (APG777), the company's most advanced program, is being initially developed for the treatment of atopic dermatitis (AD), which is the largest and one of the least penetrated I&I markets, as well as asthma. With four validated targets in its portfolio, Apogee is seeking to achieve best-in-class efficacy and dosing through monotherapies and combinations of its novel antibodies. Based on a broad pipeline and depth of leadership and expertise, the company believes it can deliver value and meaningful benefit to patients underserved by today's standard of care. We are a fast-paced company committed to building an exceptional culture, founded on our C.O.R.E. values: C aring, O riginal, R esilient and E goless and a commitment to refusing to stop at “good enough”. If this sounds like you, keep reading! 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