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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are seeking a Software Engineer to join our Platform team to design, build, and deploy the AI infrastructure that powers our world-class research team. In this role, you'll collaborate closely with AI Scientists and other engineers to enable the effective use of thousands of GPUs for training and inferencing cutting-edge biological foundation models. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role Xaira is pioneering an AI-native approach to discovering and developing the next generation of life-changing medicines. We are building predictive and agentic AI systems across drug discovery, and the X-Scientist team accelerates this mission by making AI-assisted science reliable, usable, and scalable across drug discovery workflows. On the X-Scientist team, you will work at the intersection of AI, software engineering, and therapeutic discovery. You will collaborate closely with AI scientists, engineers, platform teams, and drug discovery experts to build systems that connect AI models, biological tools, datasets, and scientific workflows. This role spans backend systems, APIs, tool-calling infrastructure, workflow orchestration, developer-facing SDKs and CLIs, and agentic interfaces that help scientists run analyses, inspect intermediate steps, and iterate on results. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are seeking a Senior Automation Engineer to design, implement, and scale automated laboratory workflows and the supporting technologies that make them reliable, traceable, and extensible. This is a hands-on lab automation and technology development role focused on automating biological workflows on liquid handling robots and integrated automation workcells, while also developing the software, data, and LIMS-connected tools needed to make laboratory operations more scalable, observable, and AI-ready. This role sits at the intersection of biology, automation, robotics, software, and data systems. You will translate scientific workflows into reliable automated processes, support production-scale execution, and help build the control layers, data interfaces, and system integrations needed for more adaptive laboratory operations. Today, most lab automation systems are powerful but rigid, where hardware and software are typically designed to execute predefined instructions, not to understand workflow context, reason about errors, or support autonomous correction. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role The Contracts Manager will work across functions and teams as a trusted partner to proactively manage the negotiation, execution, efficient tracking, and management of research and development contracts. This role requires the ability to independently draft, negotiate and manage a variety of research and development contracts, as well as a broad understanding of life sciences and general business transactions and related legal issues. Reporting to the Sr Director, Strategic Contracts and Procurement, the Contracts Manager will be responsible for efficiently managing a large volume and variety of contracts. This position will have high visibility across the organization and will require a pro-active, positive, and professional approach. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role Xaira is seeking a highly motivated and experienced Principal Scientist to join our Functional Genomics team with a focus on high-throughput perturbation platforms and single-cell genomics technologies. The ideal candidate will bring deep expertise in CRISPR-based screening approaches, perturb-seq, and large-scale functional genomics workflows, with experience generating high-quality datasets to support both therapeutic discovery and AI/ML modeling initiatives. This position offers the opportunity to contribute to cutting-edge efforts at the intersection of functional genomics, machine learning, and disease biology. You will work closely with AI/ML scientists, computational biologists, automation engineers, and disease biology teams to develop scalable perturbation workflows, implement new technologies, and drive high-quality data generation and experimental innovation across multiple therapeutic areas. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are building foundation models for biological systems, focusing on learning from complex, multimodal data. Our approach combines representation learning and generative modeling to capture structure, variation, and latent organization in high-dimensional settings. We work with both image-based data and high-dimensional molecular (omics) measurements, treating them as complementary views of the same underlying system. Our goal is to develop models that can both encode rich representations and generate or infer missing aspects from partial observations. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are seeking an Associate Scientist to join our High-Throughput (HTP) team to support the discovery and development of innovative protein therapeutics. This role focuses on the design and execution of HTP expression, purification, and characterization campaigns. You will work at the interface of biochemistry and automation, collaborating closely with our robotics and data teams to advance candidate molecules from in silico design to physical validation. About You The successful candidate works effectively both independently and as part of cross-functional teams. Experience collaborating with discovery, process development, and analytical departments is highly desirable. We require an adaptable scientist with strong communication skills and the ability to present data across team and departmental levels. You should excel in fast-paced environments, managing multiple responsibilities and shifting priorities. You are expected to work effectively both independently and as part of a team to drive complex projects forward. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role As the Accounting Manager, reporting directly to the Corporate Controller, you will manage and administer all accounting operations and other ad hoc analysis as required. You will help manage a team of contractors supporting day to day functions while laying the groundwork for an in-house team that you will build and grow over time. This is a hands-on , high-impact role where you will have the unique opportunity to create scalable systems, establish best practices, and drive the development of a robust accounting infrastructure that positions Xaira for long-term success. Key Responsibilities - Participate in the month-end, quarter-end and year-end financial close process, preparing journal entries, balance sheet and income statement account reconciliations and analyses for various accounts timely, including but not limited to prepaids, accruals, leases (ASC 842), fixed assets and account reconciliations. - Prepare the monthly management financial packages (with analysis) and other", "parental_leave_weeks": null, "non_birth_parent_leave_weeks": null, "parental_leave_weeks_source": null, "non_birth_parent_leave_weeks_source": null, "parental_leave_source_url": null, "pto_days": null, "unlimited_pto": false, "sabbatical_eligible": false, "family_friendly_score": 44, "benefit_verified": false, "benefit_last_verified": null, "hire_states_allowed": [], "state_eligibility_source": null, "state_eligibility_enriched_at": null, "llm_quality_pass_at": null, "seniority": "senior", "years_experience_min": 5, "years_experience_max": 9, "role_function": "finance", "employer_industry": null, "employer_size": null, "quality_score": 55, "travel_pct": null, "requires_shift": null, "shift_type": "unknown", "shift_type_source": null, "weekend_work": "unknown", "weekend_work_source": null, "relocation_assistance_source": null, "contractor_w2": "unknown", "required_timezone": null, "fertility_family_building_benefits_source": null, "mental_health_support_source": null, "adoption_assistance_offered_source": null, "childcare_subsidy_source": null, "learning_budget_offered_source": null, "surrogacy_assistance_offered_source": null, "cover_letter_required": null, "cover_letter_required_source": null, "assessment_required": null, "assessment_required_source": null, "application_deadline": null, "application_deadline_source": null, "visa_sponsorship": false, "us_citizenship_required": false, "security_clearance": "none", "education_required": "none", "roll_up_count": null, "roll_up_total_locations": null, "explanations": [] }, { "id": "dabe6d848336b25588eb684b0d8e870f", "title": "Senior Director, Strategic Sourcing and Contracts", "employer_name": "Xaira", "employer_slug": "xaira", "location_text": "South San Francisco, California, United States", "country": "US", "employment_type": "contract", "remote_status": "unspecified", "remote_status_source": null, "remote_status_enriched_at": null, "days_in_office": null, "timezone_overlap_hours": 6, "salary_min": 215000, "salary_max": 280000, "salary_min_source": null, "salary_max_source": null, "salary_currency": "USD", "salary_type": "base_plus_commission", "salary_type_source": null, "salary_type_enriched_at": null, "salary_period": "year", "base_salary_min": 215000, "base_salary_max": 280000, "salary_disclosed": true, "equity_included": true, "equity_included_source": null, "equity_type": [ "options" ], "k401_match": null, "match_401k_pct": null, "match_401k_pct_source": null, "k401_match_source_url": null, "k401_match_source_fields": [], "k401_contribution_source_url": null, "k401_contribution_source_fields": [], "profit_sharing": false, "bonus_offered": true, "mental_health_support": null, "childcare_subsidy": null, "fertility_family_building_benefits": null, "adoption_assistance_offered": null, "surrogacy_assistance_offered": null, "learning_budget_offered": null, "relocation_assistance": null, "top_startup_sources": [], "posted_at": "2026-04-24T00:21:32.000Z", "apply_url": "https://job-boards.greenhouse.io/xairatherapeutics/jobs/5036679007", "apply_url_verified": false, "ats": "greenhouse", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "Senior Director, Strategic Sourcing and Contracts South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. Role Overview The Senior Director, Supply Chain and Strategic Sourcing will lead and integrate Xaira's supply chain, procurement, and contract governance functions, ensuring reliable access to the external partners, platforms, and services that support Research, Biomedical AI, Platform Engineering, and Corporate teams. This role is responsible for establishing disciplined sourcing strategy, strengthening vendor management, building contract governance infrastructure, and ensuring operational continuity across critical suppliers and service providers. The individual will provide strategic oversight while elevating two existing functions, procurement and contracts, into a cohesive, scalable supply chain capability. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role The Senior Director, Project Management, will lead cross-functional execution of the company's most complex scientific and platform initiatives, ensuring work across biology, computational science, protein design, and engineering teams progresses with clarity, alignment, and momentum.Working closely with scientific and technical leadership, this individual translates strategic priorities into well-structured projects with clear scope, milestones, ownership, and dependencies. The role requires strong project management discipline combined with a product lens, helping teams prioritize work based on impact, define clear outcomes, and focus effort on the highest-value initiatives.Operating at the center of scientific, technical, and organizational execution, this leader brings structure to complex work while enabling teams to move quickly in a discovery-driven environment. Key Responsibilities Project Leadership - Lead planning and execution of complex, cross-functional projects spanning research, computational science, protein design, and engineering teams - Translate strategic priorities into clearly structured projects with defined", "parental_leave_weeks": null, "non_birth_parent_leave_weeks": null, "parental_leave_weeks_source": null, "non_birth_parent_leave_weeks_source": null, "parental_leave_source_url": null, "pto_days": null, "unlimited_pto": false, "sabbatical_eligible": false, "family_friendly_score": 44, "benefit_verified": false, "benefit_last_verified": null, "hire_states_allowed": [], "state_eligibility_source": null, "state_eligibility_enriched_at": null, "llm_quality_pass_at": null, "seniority": "staff_plus", "years_experience_min": 10, "years_experience_max": null, "role_function": "finance", "employer_industry": null, "employer_size": null, "quality_score": 55, "travel_pct": null, "requires_shift": null, "shift_type": "unknown", "shift_type_source": null, "weekend_work": "unknown", "weekend_work_source": null, "relocation_assistance_source": null, "contractor_w2": "unknown", "required_timezone": null, "fertility_family_building_benefits_source": null, "mental_health_support_source": null, "adoption_assistance_offered_source": null, "childcare_subsidy_source": null, "learning_budget_offered_source": null, "surrogacy_assistance_offered_source": null, "cover_letter_required": null, "cover_letter_required_source": null, "assessment_required": null, "assessment_required_source": null, "application_deadline": null, "application_deadline_source": null, "visa_sponsorship": false, "us_citizenship_required": false, "security_clearance": "none", "education_required": "doctorate", "roll_up_count": null, "roll_up_total_locations": null, "explanations": [] }, { "id": "3876c1cc9d4a6b65bee4ed71561534b0", "title": "Vice President, Information Technology", "employer_name": "Xaira", "employer_slug": "xaira", "location_text": "South San Francisco, California, United States", "country": "US", "employment_type": "unknown", "remote_status": "unspecified", "remote_status_source": null, "remote_status_enriched_at": null, "days_in_office": null, "timezone_overlap_hours": 6, "salary_min": 300000, "salary_max": 325000, "salary_min_source": null, "salary_max_source": null, "salary_currency": "USD", "salary_type": "base_plus_commission", "salary_type_source": null, "salary_type_enriched_at": null, "salary_period": "year", "base_salary_min": 300000, "base_salary_max": 325000, "salary_disclosed": true, "equity_included": true, "equity_included_source": null, "equity_type": [ "options" ], "k401_match": null, "match_401k_pct": null, "match_401k_pct_source": null, "k401_match_source_url": null, "k401_match_source_fields": [], "k401_contribution_source_url": null, "k401_contribution_source_fields": [], "profit_sharing": false, "bonus_offered": true, "mental_health_support": null, "childcare_subsidy": null, "fertility_family_building_benefits": null, "adoption_assistance_offered": null, "surrogacy_assistance_offered": null, "learning_budget_offered": null, "relocation_assistance": null, "top_startup_sources": [], "posted_at": "2026-04-13T23:25:09.000Z", "apply_url": "https://job-boards.greenhouse.io/xairatherapeutics/jobs/5107095007", "apply_url_verified": false, "ats": "greenhouse", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "Vice President, Information Technology South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are a technology-driven biotechnology company using AI to compress the timelines of drug discovery and development. At Xaira, we believe that becoming a truly AI-native organization is not a future ambition. It is a present imperative. The way we build our infrastructure, adopt our tools, and lead our technology function will determine how fast we can move and how far we can go.The optimal candidate is energized and enthused to push the frontier of what an enterprise can do with all available and evolving AI tools. We are seeking a VP of Information Technology to serve as the senior-most IT leader and AI evangelist on the team. The optimal candidate is energized and enthused to push the frontier of what an enterprise can do with all available and evolving AI tools.This role will own the full scope of IT: strategy, security, infrastructure,", "parental_leave_weeks": null, "non_birth_parent_leave_weeks": null, "parental_leave_weeks_source": null, "non_birth_parent_leave_weeks_source": null, "parental_leave_source_url": null, "pto_days": null, "unlimited_pto": false, "sabbatical_eligible": false, "family_friendly_score": 44, "benefit_verified": false, "benefit_last_verified": null, "hire_states_allowed": [], "state_eligibility_source": null, "state_eligibility_enriched_at": null, "llm_quality_pass_at": null, "seniority": "staff_plus", "years_experience_min": 8, "years_experience_max": 12, "role_function": "product", "employer_industry": null, "employer_size": null, "quality_score": 55, "travel_pct": null, "requires_shift": null, "shift_type": "unknown", "shift_type_source": null, "weekend_work": "unknown", "weekend_work_source": null, "relocation_assistance_source": null, "contractor_w2": "unknown", "required_timezone": null, "fertility_family_building_benefits_source": null, "mental_health_support_source": null, "adoption_assistance_offered_source": null, "childcare_subsidy_source": null, "learning_budget_offered_source": null, "surrogacy_assistance_offered_source": null, "cover_letter_required": null, "cover_letter_required_source": null, "assessment_required": null, "assessment_required_source": null, "application_deadline": null, "application_deadline_source": null, "visa_sponsorship": false, "us_citizenship_required": false, "security_clearance": "none", "education_required": "masters", "roll_up_count": null, "roll_up_total_locations": null, "explanations": [] }, { "id": "88cf562e777e56fa783513e7e5ac9d20", "title": "BioMedical AI Research Engineer", "employer_name": "Xaira", "employer_slug": "xaira", "location_text": "South San Francisco, California, United States", "country": "US", "employment_type": "unknown", "remote_status": "unspecified", "remote_status_source": null, "remote_status_enriched_at": null, "days_in_office": null, "timezone_overlap_hours": 6, "salary_min": 190000, "salary_max": 280000, "salary_min_source": null, "salary_max_source": null, "salary_currency": "USD", "salary_type": "base_plus_commission", "salary_type_source": null, "salary_type_enriched_at": null, "salary_period": "year", "base_salary_min": 190000, "base_salary_max": 280000, "salary_disclosed": true, "equity_included": true, "equity_included_source": null, "equity_type": [ "options" ], "k401_match": null, "match_401k_pct": null, "match_401k_pct_source": null, "k401_match_source_url": null, "k401_match_source_fields": [], "k401_contribution_source_url": null, "k401_contribution_source_fields": [], "profit_sharing": false, "bonus_offered": true, "mental_health_support": null, "childcare_subsidy": null, "fertility_family_building_benefits": null, "adoption_assistance_offered": null, "surrogacy_assistance_offered": null, "learning_budget_offered": null, "relocation_assistance": null, "top_startup_sources": [], "posted_at": "2026-03-31T20:14:54.000Z", "apply_url": "https://job-boards.greenhouse.io/xairatherapeutics/jobs/5005200007", "apply_url_verified": false, "ats": "greenhouse", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "BioMedical AI Research Engineer South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are seeking a Biomedical AI Engineer to design and deploy agentic AI systems that can reason over biomedical knowledge, plan multi-step analyses, and autonomously integrate diverse scientific data sources to accelerate therapeutic discovery. This role goes beyond traditional LLM + RAG pipelines. You will build AI agents that can retrieve, synthesize, evaluate, and act on biomedical information across literature, omics datasets, and clinical records operating as intelligent systems embedded within discovery workflows. Key Responsibilities - Design and implement agentic AI architectures capable of multi-step reasoning, planning, and tool use in biomedical contexts. - Develop LLM-based agents that dynamically retrieve, rank, and synthesize knowledge from scientific literature, knowledge graphs, omics datasets, and clinical data. - Build memory and feedback mechanisms that allow agents to refine hypotheses, update context, and adapt to evolving data. - Integrate external tools (analysis pipelines, simulation engines, statistical models,", "parental_leave_weeks": null, "non_birth_parent_leave_weeks": null, "parental_leave_weeks_source": null, "non_birth_parent_leave_weeks_source": null, "parental_leave_source_url": null, "pto_days": null, "unlimited_pto": false, "sabbatical_eligible": false, "family_friendly_score": 44, "benefit_verified": false, "benefit_last_verified": null, "hire_states_allowed": [], "state_eligibility_source": null, "state_eligibility_enriched_at": null, "llm_quality_pass_at": null, "seniority": "mid", "years_experience_min": 3, "years_experience_max": 7, "role_function": "engineering", "employer_industry": null, "employer_size": null, "quality_score": 55, "travel_pct": null, "requires_shift": null, "shift_type": "unknown", "shift_type_source": null, "weekend_work": "unknown", "weekend_work_source": null, "relocation_assistance_source": null, "contractor_w2": "unknown", "required_timezone": null, "fertility_family_building_benefits_source": null, "mental_health_support_source": null, "adoption_assistance_offered_source": null, "childcare_subsidy_source": null, "learning_budget_offered_source": null, "surrogacy_assistance_offered_source": null, "cover_letter_required": null, "cover_letter_required_source": null, "assessment_required": null, "assessment_required_source": null, "application_deadline": null, "application_deadline_source": null, "visa_sponsorship": false, "us_citizenship_required": false, "security_clearance": "none", "education_required": "none", "roll_up_count": null, "roll_up_total_locations": null, "explanations": [] }, { "id": "acd851f2416ff757cbe1aa84452b65df", "title": "AI in Residence", "employer_name": "Xaira", "employer_slug": "xaira", "location_text": "South San Francisco, California, United States", "country": "US", "employment_type": "unknown", "remote_status": "unspecified", "remote_status_source": null, "remote_status_enriched_at": null, "days_in_office": null, "timezone_overlap_hours": 6, "salary_min": 10000, "salary_max": 15000, "salary_min_source": null, "salary_max_source": null, "salary_currency": "USD", "salary_type": "base", "salary_type_source": null, "salary_type_enriched_at": null, "salary_period": "month", "base_salary_min": 10000, "base_salary_max": 15000, "salary_disclosed": true, "equity_included": false, "equity_included_source": null, "equity_type": [ "none" ], "k401_match": null, "match_401k_pct": null, "match_401k_pct_source": null, "k401_match_source_url": null, "k401_match_source_fields": [], "k401_contribution_source_url": null, "k401_contribution_source_fields": [], "profit_sharing": false, "bonus_offered": false, "mental_health_support": null, "childcare_subsidy": null, "fertility_family_building_benefits": null, "adoption_assistance_offered": null, "surrogacy_assistance_offered": null, "learning_budget_offered": null, "relocation_assistance": null, "top_startup_sources": [], "posted_at": "2026-03-25T19:11:20.000Z", "apply_url": "https://job-boards.greenhouse.io/xairatherapeutics/jobs/5089321007", "apply_url_verified": false, "ats": "greenhouse", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "AI in Residence South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. AI in Residence AI in Residence is a highly selective role at the intersection of frontier machine learning and drug discovery. Designed as an industry alternative to a traditional postdoctoral position, the program is for exceptional researchers and engineers who want to apply advanced AI to real biomedical problems end to end, from data to deployed systems. Residents join a small cohort working on high-impact AI efforts across Xaira. You'll collaborate closely with AI scientists, research engineers, and drug discovery teams to design, build, and ship machine learning capabilities that directly influence therapeutic programs. This is hands-on, system-level work with real scientific consequence. We're looking for candidates with technical depth, intellectual independence, strong research judgment, and evidence of delivering high-quality work-whether through publications, open-source, or production systems. What You'll Do - Develop and advance ML models for biological, preclinical, and translational datasets (e.g., multimodal omics, imaging, text,", "parental_leave_weeks": null, "non_birth_parent_leave_weeks": null, "parental_leave_weeks_source": null, "non_birth_parent_leave_weeks_source": null, "parental_leave_source_url": null, "pto_days": null, "unlimited_pto": false, "sabbatical_eligible": false, "family_friendly_score": 44, "benefit_verified": false, "benefit_last_verified": null, "hire_states_allowed": [], "state_eligibility_source": null, "state_eligibility_enriched_at": null, "llm_quality_pass_at": null, "seniority": "mid", "years_experience_min": 3, "years_experience_max": 7, "role_function": "other", "employer_industry": null, "employer_size": null, "quality_score": 55, "travel_pct": null, "requires_shift": null, "shift_type": "unknown", "shift_type_source": null, "weekend_work": "unknown", "weekend_work_source": null, "relocation_assistance_source": null, "contractor_w2": "unknown", "required_timezone": null, "fertility_family_building_benefits_source": null, "mental_health_support_source": null, "adoption_assistance_offered_source": null, "childcare_subsidy_source": null, "learning_budget_offered_source": null, "surrogacy_assistance_offered_source": null, "cover_letter_required": null, "cover_letter_required_source": null, "assessment_required": null, "assessment_required_source": null, "application_deadline": null, "application_deadline_source": null, "visa_sponsorship": false, "us_citizenship_required": false, "security_clearance": "none", "education_required": "doctorate", "roll_up_count": null, "roll_up_total_locations": null, "explanations": [] }, { "id": "4b50925bcb1c183188172544bb748a1a", "title": "Senior Research Associate/Associate Scientist, Display Technology (Contract)", "employer_name": "Xaira", "employer_slug": "xaira", "location_text": "South San Francisco, California, United States", "country": "US", "employment_type": "contract", "remote_status": "unspecified", "remote_status_source": null, "remote_status_enriched_at": null, "days_in_office": null, "timezone_overlap_hours": 6, "salary_min": 45, "salary_max": 60, "salary_min_source": null, "salary_max_source": null, "salary_currency": "USD", "salary_type": "base", "salary_type_source": null, "salary_type_enriched_at": null, "salary_period": "hour", "base_salary_min": 45, "base_salary_max": 60, "salary_disclosed": true, "equity_included": false, "equity_included_source": null, "equity_type": [ "none" ], "k401_match": null, "match_401k_pct": null, "match_401k_pct_source": null, "k401_match_source_url": null, "k401_match_source_fields": [], "k401_contribution_source_url": null, "k401_contribution_source_fields": [], "profit_sharing": false, "bonus_offered": false, "mental_health_support": null, "childcare_subsidy": null, "fertility_family_building_benefits": null, "adoption_assistance_offered": null, "surrogacy_assistance_offered": null, "learning_budget_offered": null, "relocation_assistance": null, "top_startup_sources": [], "posted_at": "2026-03-04T22:59:24.000Z", "apply_url": "https://job-boards.greenhouse.io/xairatherapeutics/jobs/5068166007", "apply_url_verified": false, "ats": "greenhouse", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "Senior Research Associate/Associate Scientist, Display Technology (Contract) South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role You are an enthusiastic protein biochemist who takes pride in your bench execution skills. Your passion lies in display technology, drug discovery and developing novel treatments for patients. You are conscientious, detail-oriented, and organized. Collaboration comes naturally to you, and you thrive in a fast-paced environment where pushing the boundaries of what is possible is the norm. Responsibilities - Build, adapt, and automate display systems to facilitate AI antibody design. - Establish, develop, and/or optimize cutting edge technologies to enable data generation at scale for AI model training or evaluation - Design and apply multiple innovative selection techniques to provide data at scale based on ML training needs. - Design, setup, optimize, and use automation to characterize affinity and function at the clonal level. - Contribute to the preparation of technical reports and presentations. Qualifications - Significant hands-on experience with", "parental_leave_weeks": null, "non_birth_parent_leave_weeks": null, "parental_leave_weeks_source": null, "non_birth_parent_leave_weeks_source": null, "parental_leave_source_url": null, "pto_days": null, "unlimited_pto": false, "sabbatical_eligible": false, "family_friendly_score": 44, "benefit_verified": false, "benefit_last_verified": null, "hire_states_allowed": [], "state_eligibility_source": null, "state_eligibility_enriched_at": null, "llm_quality_pass_at": null, "seniority": "senior", "years_experience_min": 5, "years_experience_max": 9, "role_function": "data", "employer_industry": null, "employer_size": null, "quality_score": 55, "travel_pct": null, "requires_shift": null, "shift_type": "unknown", "shift_type_source": null, "weekend_work": "unknown", "weekend_work_source": null, "relocation_assistance_source": null, "contractor_w2": "unknown", "required_timezone": null, "fertility_family_building_benefits_source": null, "mental_health_support_source": null, "adoption_assistance_offered_source": null, "childcare_subsidy_source": null, "learning_budget_offered_source": null, "surrogacy_assistance_offered_source": null, "cover_letter_required": null, "cover_letter_required_source": null, "assessment_required": null, "assessment_required_source": null, "application_deadline": null, "application_deadline_source": null, "visa_sponsorship": false, "us_citizenship_required": false, "security_clearance": "none", "education_required": "masters", "roll_up_count": null, "roll_up_total_locations": null, "explanations": [] }, { "id": "90d9d09e7374384911657b232a7f0b1a", "title": "Senior Research Associate/ Associate Scientist, Platform and Assay Development", "employer_name": "Xaira", "employer_slug": "xaira", "location_text": "South San Francisco, California, United States", "country": "US", "employment_type": "unknown", "remote_status": "unspecified", "remote_status_source": null, "remote_status_enriched_at": null, "days_in_office": null, "timezone_overlap_hours": 6, "salary_min": 101000, "salary_max": 126000, "salary_min_source": null, "salary_max_source": null, "salary_currency": "USD", "salary_type": "base_plus_commission", "salary_type_source": null, "salary_type_enriched_at": null, "salary_period": "year", "base_salary_min": 101000, "base_salary_max": 126000, "salary_disclosed": true, "equity_included": true, "equity_included_source": null, "equity_type": [ "options" ], "k401_match": null, "match_401k_pct": null, "match_401k_pct_source": null, "k401_match_source_url": null, "k401_match_source_fields": [], "k401_contribution_source_url": null, "k401_contribution_source_fields": [], "profit_sharing": false, "bonus_offered": true, "mental_health_support": null, "childcare_subsidy": null, "fertility_family_building_benefits": null, "adoption_assistance_offered": null, "surrogacy_assistance_offered": null, "learning_budget_offered": null, "relocation_assistance": null, "top_startup_sources": [], "posted_at": "2026-02-18T17:32:41.000Z", "apply_url": "https://job-boards.greenhouse.io/xairatherapeutics/jobs/5052774007", "apply_url_verified": false, "ats": "greenhouse", "url_last_checked_alive": null, "removed_at": null, "description_excerpt": "Senior Research Associate/ Associate Scientist, Platform and Assay Development South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role - We are seeking a highly motivated Scientist with strong hands-on experience in assay development, immunology, and cell biology to support the discovery and characterization of novel therapeutic antibodies. This role is ideal for an experimentalist who enjoys independently designing and executing complex biological assays, troubleshooting workflows, and generating high-quality data to support drug discovery programs. - The ideal candidate has deep experience developing functional antibody assays and is comfortable operating in fast-paced, evolving research environments. You will work closely with cross-functional teams spanning protein engineering, automation, and computational biology to support target validation and therapeutic development efforts. 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The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are looking for an AI Scientist to join our team at the intersection of machine learning and single-cell biology. This role will focus on developing and applying foundation models to large-scale perturb-seq and single-cell datasets to uncover new biological mechanisms and therapeutic opportunities. 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Software Engineer, ML Platform at Xaira - Seattle, Washington, United States - Software Engineer, ML Platform Seattle, Washington, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are seeking a Software Engineer to join our Platform team to design, build, and deploy the AI infrastructure that powers our world-class research team. In this role, you'll collaborate closely with AI Scientists and other engineers to enable the effective use of thousands of GPUs for training and inferencing cutting-edge biological foundation models. This role spans a range of problems and skillsets, ranging from MLOps of cutting-edge GPU clusters, to backend engineering of control plane APIs. Our ideal candidate has an opinion about slurm or kubernetes for model training, cares about maximizing bandwidth from the storage subsystems to the GPU, and can build the API paved path for submitting training jobs that are able to dispatch to multiple clusters. What You Will Do - Develop and improve our model training system, responsible for dispatching distributed training jobs to clusters across multiple clouds. - Deploy

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Software Engineer, X-Scientist at Xaira - South San Francisco, California, United States - Software Engineer, X-Scientist South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role Xaira is pioneering an AI-native approach to discovering and developing the next generation of life-changing medicines. We are building predictive and agentic AI systems across drug discovery, and the X-Scientist team accelerates this mission by making AI-assisted science reliable, usable, and scalable across drug discovery workflows. On the X-Scientist team, you will work at the intersection of AI, software engineering, and therapeutic discovery. You will collaborate closely with AI scientists, engineers, platform teams, and drug discovery experts to build systems that connect AI models, biological tools, datasets, and scientific workflows. This role spans backend systems, APIs, tool-calling infrastructure, workflow orchestration, developer-facing SDKs and CLIs, and agentic interfaces that help scientists run analyses, inspect intermediate steps, and iterate on results. What You'll Do - Backend systems and APIs that connect AI models to scientific tools, datasets, and analysis workflows - Tool-calling infrastructure, CLIs, SDKs, and

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Senior Automation Engineer at Xaira - South San Francisco, California, United States - Senior Automation Engineer South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are seeking a Senior Automation Engineer to design, implement, and scale automated laboratory workflows and the supporting technologies that make them reliable, traceable, and extensible. This is a hands-on lab automation and technology development role focused on automating biological workflows on liquid handling robots and integrated automation workcells, while also developing the software, data, and LIMS-connected tools needed to make laboratory operations more scalable, observable, and AI-ready. This role sits at the intersection of biology, automation, robotics, software, and data systems. You will translate scientific workflows into reliable automated processes, support production-scale execution, and help build the control layers, data interfaces, and system integrations needed for more adaptive laboratory operations. Today, most lab automation systems are powerful but rigid, where hardware and software are typically designed to execute predefined instructions, not to understand workflow context, reason about errors, or support autonomous correction. This

", "datePosted": "2026-06-05T02:51:29.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "6b29263dcb34a37fc837a344a076f89d" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "estimatedSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 152000, "maxValue": 190000, "unitText": "YEAR" }, "description": "Base salary plus commission" }, "directApply": false, "incentiveCompensation": "Equity (Options); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "Masters", "url": "https://fewerjobs.com/jobs/xaira/senior-automation-engineer-6b29263d" } }, { "@type": "ListItem", "position": 4, "url": "https://fewerjobs.com/jobs/xaira/contracts-manager-9ed06be9", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Contracts Manager", "description": "

Contracts Manager at Xaira - Seattle, Washington, United States; South San Francisco, California, United States - Contracts Manager Seattle, Washington, United States; South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role The Contracts Manager will work across functions and teams as a trusted partner to proactively manage the negotiation, execution, efficient tracking, and management of research and development contracts. This role requires the ability to independently draft, negotiate and manage a variety of research and development contracts, as well as a broad understanding of life sciences and general business transactions and related legal issues. Reporting to the Sr Director, Strategic Contracts and Procurement, the Contracts Manager will be responsible for efficiently managing a large volume and variety of contracts. This position will have high visibility across the organization and will require a pro-active, positive, and professional approach. Key Responsibilities - Independently prepare, negotiate, and manage a wide variety of contracts related to the company's general business and Research and Development needs, including Master Service Agreements and associated work orders, License Agreements (including

", "datePosted": "2026-06-01T20:21:15.000Z", "employmentType": "CONTRACTOR", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "9ed06be9b6bdded861cb8bd0489c2b33" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "Seattle, Washington, United States; South San Francisco" } }, "estimatedSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 124000, "maxValue": 155000, "unitText": "YEAR" }, "description": "Base salary plus commission" }, "directApply": false, "incentiveCompensation": "Equity (Options); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "Masters", "url": "https://fewerjobs.com/jobs/xaira/contracts-manager-9ed06be9" } }, { "@type": "ListItem", "position": 5, "url": "https://fewerjobs.com/jobs/xaira/principal-scientist-functional-genomics-4e0ba4e3", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Principal Scientist, Functional Genomics", "description": "

Principal Scientist, Functional Genomics at Xaira - South San Francisco, California, United States - Principal Scientist, Functional Genomics South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role Xaira is seeking a highly motivated and experienced Principal Scientist to join our Functional Genomics team with a focus on high-throughput perturbation platforms and single-cell genomics technologies. The ideal candidate will bring deep expertise in CRISPR-based screening approaches, perturb-seq, and large-scale functional genomics workflows, with experience generating high-quality datasets to support both therapeutic discovery and AI/ML modeling initiatives. This position offers the opportunity to contribute to cutting-edge efforts at the intersection of functional genomics, machine learning, and disease biology. You will work closely with AI/ML scientists, computational biologists, automation engineers, and disease biology teams to develop scalable perturbation workflows, implement new technologies, and drive high-quality data generation and experimental innovation across multiple therapeutic areas. Key Responsibilities - Lead high-throughput perturbation and functional genomics efforts supporting therapeutic discovery and AI/ML-driven research initiatives - Develop and implement advanced functional genomics technologies, including perturb-seq, CRISPRi/a, and

", "datePosted": "2026-05-29T23:36:00.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "4e0ba4e32382cd6c87b00b1ed6419c42" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "estimatedSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 175000, "maxValue": 205000, "unitText": "YEAR" }, "description": "Base salary plus commission" }, "directApply": false, "incentiveCompensation": "Equity (Options); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 96 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/xaira/principal-scientist-functional-genomics-4e0ba4e3" } }, { "@type": "ListItem", "position": 6, "url": "https://fewerjobs.com/jobs/xaira/ai-scientist-biomedical-multimodal-modeling-27a9ff17", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "AI Scientist - Biomedical Multimodal Modeling", "description": "

AI Scientist - Biomedical Multimodal Modeling at Xaira - South San Francisco, California, United States - AI Scientist - Biomedical Multimodal Modeling South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are building foundation models for biological systems, focusing on learning from complex, multimodal data. Our approach combines representation learning and generative modeling to capture structure, variation, and latent organization in high-dimensional settings. We work with both image-based data and high-dimensional molecular (omics) measurements, treating them as complementary views of the same underlying system. Our goal is to develop models that can both encode rich representations and generate or infer missing aspects from partial observations. What You'll Do - Develop multimodal foundation models spanning image and molecular data - Design approaches that unify representation learning and generative modeling - Train large-scale models on structured, high-dimensional datasets - Explore cross-modal alignment, prediction, and generation - Build scalable systems for data processing, training, and evaluation - Work in a research-driven environment with evolving problem definitions What We're Looking For Strong background in deep

", "datePosted": "2026-05-04T20:02:38.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "27a9ff175bc105410e85ca8ff335a6ea" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "estimatedSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 170000, "maxValue": 240000, "unitText": "YEAR" }, "description": "Base salary plus commission" }, "directApply": false, "incentiveCompensation": "Equity (Options); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 36 }, "educationRequirements": "no requirements", "url": "https://fewerjobs.com/jobs/xaira/ai-scientist-biomedical-multimodal-modeling-27a9ff17" } }, { "@type": "ListItem", "position": 7, "url": "https://fewerjobs.com/jobs/xaira/associate-scientist-bea3dbb4", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Associate Scientist", "description": "

Associate Scientist at Xaira - South San Francisco, California, United States - Associate Scientist South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are seeking an Associate Scientist to join our High-Throughput (HTP) team to support the discovery and development of innovative protein therapeutics. This role focuses on the design and execution of HTP expression, purification, and characterization campaigns. You will work at the interface of biochemistry and automation, collaborating closely with our robotics and data teams to advance candidate molecules from in silico design to physical validation. About You The successful candidate works effectively both independently and as part of cross-functional teams. Experience collaborating with discovery, process development, and analytical departments is highly desirable. We require an adaptable scientist with strong communication skills and the ability to present data across team and departmental levels. You should excel in fast-paced environments, managing multiple responsibilities and shifting priorities. You are expected to work effectively both independently and as part of a team to drive complex projects forward. This

", "datePosted": "2026-04-24T01:03:55.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "bea3dbb4bd9cadd0dd3a696d07f08dbf" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "estimatedSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 101000, "maxValue": 126000, "unitText": "YEAR" }, "description": "Base salary plus commission" }, "directApply": false, "incentiveCompensation": "Equity (Options); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 36 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/xaira/associate-scientist-bea3dbb4" } }, { "@type": "ListItem", "position": 8, "url": "https://fewerjobs.com/jobs/xaira/accounting-manager-384a647d", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Accounting Manager", "description": "

Accounting Manager at Xaira - South San Francisco, California, United States - Accounting Manager South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role As the Accounting Manager, reporting directly to the Corporate Controller, you will manage and administer all accounting operations and other ad hoc analysis as required. You will help manage a team of contractors supporting day to day functions while laying the groundwork for an in-house team that you will build and grow over time. This is a hands-on , high-impact role where you will have the unique opportunity to create scalable systems, establish best practices, and drive the development of a robust accounting infrastructure that positions Xaira for long-term success. Key Responsibilities - Participate in the month-end, quarter-end and year-end financial close process, preparing journal entries, balance sheet and income statement account reconciliations and analyses for various accounts timely, including but not limited to prepaids, accruals, leases (ASC 842), fixed assets and account reconciliations. - Prepare the monthly management financial packages (with analysis) and other

", "datePosted": "2026-04-24T00:27:43.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "384a647d3b7af3668f82bbec1f33a1ff" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 135000, "maxValue": 155000, "unitText": "YEAR" } }, "directApply": false, "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "no requirements", "url": "https://fewerjobs.com/jobs/xaira/accounting-manager-384a647d" } }, { "@type": "ListItem", "position": 9, "url": "https://fewerjobs.com/jobs/xaira/senior-director-strategic-sourcing-and-contracts-dabe6d84", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Senior Director, Strategic Sourcing and Contracts", "description": "

Senior Director, Strategic Sourcing and Contracts at Xaira - South San Francisco, California, United States - Senior Director, Strategic Sourcing and Contracts South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. Role Overview The Senior Director, Supply Chain and Strategic Sourcing will lead and integrate Xaira's supply chain, procurement, and contract governance functions, ensuring reliable access to the external partners, platforms, and services that support Research, Biomedical AI, Platform Engineering, and Corporate teams. This role is responsible for establishing disciplined sourcing strategy, strengthening vendor management, building contract governance infrastructure, and ensuring operational continuity across critical suppliers and service providers. The individual will provide strategic oversight while elevating two existing functions, procurement and contracts, into a cohesive, scalable supply chain capability. Operating at the intersection of research, technology infrastructure, and external partnerships, This role is responsible for bringing strategic focus to how Xaira engages its external partners, ensuring that sourcing, vendor, and contract decisions serve the company's mission, growth, and long-term goals Key Responsibilities Supply Chain Leadership - Develop and lead overall supply chain strategy -

", "datePosted": "2026-04-24T00:21:32.000Z", "employmentType": "CONTRACTOR", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "dabe6d848336b25588eb684b0d8e870f" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "estimatedSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 215000, "maxValue": 280000, "unitText": "YEAR" }, "description": "Base salary plus commission" }, "directApply": false, "incentiveCompensation": "Equity (Options); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 120 }, "educationRequirements": "no requirements", "url": "https://fewerjobs.com/jobs/xaira/senior-director-strategic-sourcing-and-contracts-dabe6d84" } }, { "@type": "ListItem", "position": 10, "url": "https://fewerjobs.com/jobs/xaira/senior-director-project-management-a19bf464", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Senior Director, Project Management", "description": "

Senior Director, Project Management at Xaira - South San Francisco, California, United States - Senior Director, Project Management South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role The Senior Director, Project Management, will lead cross-functional execution of the company's most complex scientific and platform initiatives, ensuring work across biology, computational science, protein design, and engineering teams progresses with clarity, alignment, and momentum.Working closely with scientific and technical leadership, this individual translates strategic priorities into well-structured projects with clear scope, milestones, ownership, and dependencies. The role requires strong project management discipline combined with a product lens, helping teams prioritize work based on impact, define clear outcomes, and focus effort on the highest-value initiatives.Operating at the center of scientific, technical, and organizational execution, this leader brings structure to complex work while enabling teams to move quickly in a discovery-driven environment. Key Responsibilities Project Leadership - Lead planning and execution of complex, cross-functional projects spanning research, computational science, protein design, and engineering teams - Translate strategic priorities into clearly structured projects with defined

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Vice President, Information Technology at Xaira - South San Francisco, California, United States - Vice President, Information Technology South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are a technology-driven biotechnology company using AI to compress the timelines of drug discovery and development. At Xaira, we believe that becoming a truly AI-native organization is not a future ambition. It is a present imperative. The way we build our infrastructure, adopt our tools, and lead our technology function will determine how fast we can move and how far we can go.The optimal candidate is energized and enthused to push the frontier of what an enterprise can do with all available and evolving AI tools. We are seeking a VP of Information Technology to serve as the senior-most IT leader and AI evangelist on the team. The optimal candidate is energized and enthused to push the frontier of what an enterprise can do with all available and evolving AI tools.This role will own the full scope of IT: strategy, security, infrastructure,

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BioMedical AI Research Engineer at Xaira - South San Francisco, California, United States - BioMedical AI Research Engineer South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are seeking a Biomedical AI Engineer to design and deploy agentic AI systems that can reason over biomedical knowledge, plan multi-step analyses, and autonomously integrate diverse scientific data sources to accelerate therapeutic discovery. This role goes beyond traditional LLM + RAG pipelines. You will build AI agents that can retrieve, synthesize, evaluate, and act on biomedical information across literature, omics datasets, and clinical records operating as intelligent systems embedded within discovery workflows. Key Responsibilities - Design and implement agentic AI architectures capable of multi-step reasoning, planning, and tool use in biomedical contexts. - Develop LLM-based agents that dynamically retrieve, rank, and synthesize knowledge from scientific literature, knowledge graphs, omics datasets, and clinical data. - Build memory and feedback mechanisms that allow agents to refine hypotheses, update context, and adapt to evolving data. - Integrate external tools (analysis pipelines, simulation engines, statistical models,

", "datePosted": "2026-03-31T20:14:54.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "88cf562e777e56fa783513e7e5ac9d20" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "estimatedSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 190000, "maxValue": 280000, "unitText": "YEAR" }, "description": "Base salary plus commission" }, "directApply": false, "incentiveCompensation": "Equity (Options); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 36 }, "educationRequirements": "no requirements", "url": "https://fewerjobs.com/jobs/xaira/biomedical-ai-research-engineer-88cf562e" } }, { "@type": "ListItem", "position": 13, "url": "https://fewerjobs.com/jobs/xaira/ai-in-residence-acd851f2", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "AI in Residence", "description": "

AI in Residence at Xaira - South San Francisco, California, United States - AI in Residence South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. AI in Residence AI in Residence is a highly selective role at the intersection of frontier machine learning and drug discovery. Designed as an industry alternative to a traditional postdoctoral position, the program is for exceptional researchers and engineers who want to apply advanced AI to real biomedical problems end to end, from data to deployed systems. Residents join a small cohort working on high-impact AI efforts across Xaira. You'll collaborate closely with AI scientists, research engineers, and drug discovery teams to design, build, and ship machine learning capabilities that directly influence therapeutic programs. This is hands-on, system-level work with real scientific consequence. We're looking for candidates with technical depth, intellectual independence, strong research judgment, and evidence of delivering high-quality work-whether through publications, open-source, or production systems. What You'll Do - Develop and advance ML models for biological, preclinical, and translational datasets (e.g., multimodal omics, imaging, text,

", "datePosted": "2026-03-25T19:11:20.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "acd851f2416ff757cbe1aa84452b65df" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 10000, "maxValue": 15000, "unitText": "MONTH" } }, "directApply": false, "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 36 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/xaira/ai-in-residence-acd851f2" } }, { "@type": "ListItem", "position": 14, "url": "https://fewerjobs.com/jobs/xaira/senior-research-associate-associate-scientist-display-technology-contract-4b50925b", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Senior Research Associate/Associate Scientist, Display Technology (Contract)", "description": "

Senior Research Associate/Associate Scientist, Display Technology (Contract) at Xaira - South San Francisco, California, United States - Senior Research Associate/Associate Scientist, Display Technology (Contract) South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role You are an enthusiastic protein biochemist who takes pride in your bench execution skills. Your passion lies in display technology, drug discovery and developing novel treatments for patients. You are conscientious, detail-oriented, and organized. Collaboration comes naturally to you, and you thrive in a fast-paced environment where pushing the boundaries of what is possible is the norm. Responsibilities - Build, adapt, and automate display systems to facilitate AI antibody design. - Establish, develop, and/or optimize cutting edge technologies to enable data generation at scale for AI model training or evaluation - Design and apply multiple innovative selection techniques to provide data at scale based on ML training needs. - Design, setup, optimize, and use automation to characterize affinity and function at the clonal level. - Contribute to the preparation of technical reports and presentations. Qualifications - Significant hands-on experience with

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Senior Research Associate/ Associate Scientist, Platform and Assay Development at Xaira - South San Francisco, California, United States - Senior Research Associate/ Associate Scientist, Platform and Assay Development South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role - We are seeking a highly motivated Scientist with strong hands-on experience in assay development, immunology, and cell biology to support the discovery and characterization of novel therapeutic antibodies. This role is ideal for an experimentalist who enjoys independently designing and executing complex biological assays, troubleshooting workflows, and generating high-quality data to support drug discovery programs. - The ideal candidate has deep experience developing functional antibody assays and is comfortable operating in fast-paced, evolving research environments. You will work closely with cross-functional teams spanning protein engineering, automation, and computational biology to support target validation and therapeutic development efforts. Key Responsibilities - Independently design, execute, and optimize functional antibody assays to support discovery and characterization efforts - Develop and run cell-based assays focused on immune activation, cell signaling, and cell-cell interaction biology - Design experimental controls, analyze assay performance,

", "datePosted": "2026-02-18T17:32:41.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Xaira", "value": "90d9d09e7374384911657b232a7f0b1a" }, "hiringOrganization": { "@type": "Organization", "name": "Xaira" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "estimatedSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 101000, "maxValue": 126000, "unitText": "YEAR" }, "description": "Base salary plus commission" }, "directApply": false, "incentiveCompensation": "Equity (Options); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "no requirements", "url": "https://fewerjobs.com/jobs/xaira/senior-research-associate-associate-scientist-platform-and-assay-development-90d9d09e" } }, { "@type": "ListItem", "position": 16, "url": "https://fewerjobs.com/jobs/xaira/ai-scientist-biomedical-ai-61452a08", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "AI Scientist, BioMedical AI", "description": "

AI Scientist, BioMedical AI at Xaira - South San Francisco, California, United States - AI Scientist, BioMedical AI South San Francisco, California, United States About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London. About the Role We are looking for an AI Scientist to join our team at the intersection of machine learning and single-cell biology. This role will focus on developing and applying foundation models to large-scale perturb-seq and single-cell datasets to uncover new biological mechanisms and therapeutic opportunities. You will help design scalable ML architectures that can extract insight from high-dimensional perturbation data and integrate across multi-omic modalities. Key Responsibilities - Design, train, and refine foundation models tailored to perturb-seq and other single-cell datasets. Build pipelines for preprocessing, normalization, and integration of large-scale single-cell and perturbation data. - Apply ML/AI approaches to model cellular responses to perturbations and identify causal biological insights. - Collaborate with experimental biologists to align computational methods with experimental design and discovery goals. - Develop multimodal integration approaches across transcriptomic, epigenomic, and proteomic single-cell readouts. - Publish methods and results in top scientific

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