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ORIC's clinical stage product candidates include (1) rinzimetostat, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . We are seeking an experienced oncology physician to serve as a Medical Director or Senior Medical Director at ORIC Pharmaceuticals. This role provides medical leadership across one or more clinical development programs, with a primary focus on late-stage (registration-enabling) clinical trials. The position plays a critical role in shaping clinical strategy, ensuring scientific rigor, guiding regulatory interactions, and advancing programs from study design through regulatory submission. The Medical Director will work in close partnership with cross-functional teams including Clinical Operations, Regulatory Affairs, Biostatistics, Safety/Pharmacovigilance, Translational Medicine, and Medical Affairs. The role requires strong strategic thinking, hands-on execution, and the ability to lead effectively in a fast-paced biotech environment. 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The successful candidate will report to the Sr. Director of Analytical Sciences Job Description: Independently lead analytical development and product characterization activities for our drug development portfolios. Provide oversight, technical guidance and tactical direction for analytical method development, transfer, validation, release, and stability testing activities at CDMOs. Function as a subject matter expert for in-depth physical/ chemical characterization of NCEs at CROs. Independently conceptualize, design, and conduct experiments; interpret and present data and conclusions to various audience, including senior leadership. 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ORIC's clinical stage product candidates include (1) ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib (ORIC-114), a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . Reporting to the Chief Technical Officer, we are currently hiring a Director, CMC Regulatory Affairs, to join our Technical Operations team. This position is responsible for leading CMC regulatory activities and supporting all of ORIC's clinical development programs for oncology products. The role involves close collaboration with cross-functional teams including regulatory affairs, regulatory operations, quality, CMC, nonclinical, and clinical departments. Job Description: Oversee and direct all CMC regulatory strategies in compliance with global regulatory requirements for the development of ORIC's products. Provide CMC regulatory support for new and ongoing clinical trials, e.g., manage/prepare CMC document packages in support of INDs, CTAs and amendments to global regulatory agencies (RAs) and health authorities (HAs) Work collaboratively with Pharmaceutical Development, Drug Substance, and GMP Quality Assurance, in addition to Project Management, Clinical Operations, Clinical Supply, and Regulatory Operations. 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ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . Reporting to the Senior Vice President of Quality, the Director of Clinical Quality Assurance will lead the Clinical QA function and provide strategic leadership and operational oversight across global early to late-stage clinical programs. 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Senior Director, CMC Program Management at ORIC Pharmaceuticals - South San Francisco, CA, United States - Senior Director, CMC Program Management South San Francisco, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . This role requires a leader with strong business acumen to define and execute business processes that drive complex programs through global registration and commercialization. This role will play a pivotal part in bringing innovative therapies to patients by ensuring that CMC development, manufacturing, and commercialization are executed with excellence, speed, and financial discipline. This individual will also oversee project management including timelines, budgets, invoices, reports and documentation, and may assist with regulatory filings. This position reports to the Chief Technical Officer and is responsible for the following: Job Description: 1. End-to-End CMC Leadership & Cross-Functional Integration Create and execute against integrated cross-functional project plans, leading the integrated CMC strategy. Translate program strategy into cohesive development, manufacturing, and supply plans

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Associate Director, CMC Project Management at ORIC Pharmaceuticals - South San Francisco, CA, United States - Associate Director, CMC Project Management South San Francisco, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . This role requires a leader with strong business acumen to define and execute business processes that drive complex programs through global registration and commercialization. This role will play a pivotal part in bringing innovative therapies to patients by ensuring that CMC development, manufacturing, and commercialization are executed with excellence, speed, and financial discipline. This individual will also oversee project management including timelines, budgets, invoices, reports and documentation, and may assist with regulatory filings. This position reports to the Chief Technical Officer and is responsible for the following: Job Description: 1. End-to-End CMC Leadership & Cross-Functional Integration Create and execute against integrated cross-functional project plans, leading the integrated CMC strategy. Translate program strategy into cohesive development, manufacturing, and supply plans

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "d05efdb001a6d97ed1ff9133e2c49f62" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressRegion": "CA", "addressLocality": "South San Francisco" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 210000, "maxValue": 260000, "unitText": "YEAR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 108 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/associate-director-cmc-project-management-d05efdb0" } }, { "@type": "ListItem", "position": 3, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-manager-pharmacovigilance-ca58d3b0", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Senior Manager, Pharmacovigilance", "description": "

Senior Manager, Pharmacovigilance at ORIC Pharmaceuticals - San Diego, CA, United States | Remote - Senior Manager, Pharmacovigilance San Diego, CA, United States | Remote Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . The Senior Manager of Pharmacovigilance will be responsible for the execution of global pharmacovigilance activities supporting late-stage clinical development and preparation for first commercial launch of small-molecule oncology products in lung and prostate cancer. This role will ensure compliance with global safety regulations and will work closely with cross-functional partners to ensure individual case safety report (ICSR) processing, Health Authority submissions, and post-marketing safety readiness. This is a hands-on role well suited for a biotech environment requiring both operational excellence and cross-functional collaboration. Job Description: Global Drug Safety & Pharmacovigilance Operations Manage end-to-end pharmacovigilance activities for clinical trials and post-approval oncology products In partnership with Clinical Research Organizations (CROs), oversee intake, assessment, processing, medical review, and reporting of ICSRs from

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "ca58d3b08486a99169215a7d9a3432d8" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocationType": "TELECOMMUTE", "applicantLocationRequirements": { "@type": "Country", "name": "USA" }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 150000, "maxValue": 180000, "unitText": "YEAR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-manager-pharmacovigilance-ca58d3b0" } }, { "@type": "ListItem", "position": 4, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-director-quality-c8a28f35", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Senior Director, Quality", "description": "

Senior Director, Quality at ORIC Pharmaceuticals - San Diego, CA, United States - Senior Director, Quality San Diego, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . Reporting to the Senior Vice President of Quality, the Sr. Director of Quality will lead provide quality oversight of clinical development and manufacturing programs. This individual will lead the Chemistry, Manufacturing, and Controls (CMC) QA team and provide end-to-end development to manufacturing support for clinical stage programs and will develop systems to commercialize late-stage assets. This position will design, develop, and implement clinical and commercial quality strategies to ensure appropriate compliance to applicable regulatory regulations. The successful candidate will work closely with Technical Operations, Regulatory Affairs, and third-party Contract Development and Manufacturing Organizations (CDMOs) and will be responsible for all levels of studies, ranging from simple to complex and requires an in-depth understanding of GMPs, global Health Authority requirements, program management, quality

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People Operations Specialist (Contract) at ORIC Pharmaceuticals - San Diego, CA, United States - People Operations Specialist (Contract) San Diego, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) Rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) Enozertinib (ORIC-114), a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. ORIC's People Team is looking for a highly motivated People Operations Specialist to support key initiatives and the day-to-day operations of the People Team. This position will play a crucial role in creating a positive candidate and employee experience and maintaining ORIC as a best place to work for all our team members. This includes supporting the full set of employment lifecycle activities, ensuring a seamless experience for employees, managers, and the People and Payroll teams. The ideal candidate can manage multiple responsibilities and projects effectively and efficiently and is keenly interested in learning and developing in the field of Human Resources. Job Description: Talent Acquisition (60%) Schedule candidate seminars and interviews; create interview agendas and host on-site interviews as required Coordinate travel, meals, and candidate expenses Create and monitor onboarding and offboarding checklists for completion

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "INTERN", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "bef1ede624ba64cd916fe7bbe8255481" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressRegion": "CA", "addressLocality": "San Diego" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 40, "maxValue": 45, "unitText": "HOUR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 36 }, "educationRequirements": "Bachelors", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/people-operations-specialist-contract-bef1ede6" } }, { "@type": "ListItem", "position": 6, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-scientist-process-chemistry-a266d007", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Senior Scientist, Process Chemistry", "description": "

Senior Scientist, Process Chemistry at ORIC Pharmaceuticals - South San Francisco, CA, United States - Senior Scientist, Process Chemistry South San Francisco, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) ORIC-114, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. We are seeking a highly motivated process development and chemistry senior scientist. This senior scientist designs and executes multi-step experimental studies, utilizing analytical tools to ensure safe and scalable processes. They collaborate cross-functionally, author technical reports, and facilitate the transfer of technology for GMP manufacturing. Job Description: Design, planning, and execution of multi-step experimental studies to provide safe, efficient, robust and scalable processes. Independently use PAT and analytical tools and interpret data to gain reaction understanding. Share literature and available resources to support relevant precedent for process research. Perform experiments and interpret data (calorimetry, TGA, DSC) to safely scale reactions. Author development reports and technical packages, and author/review relevant sections in health authority filings (including INDs, NDAs, annual reports, and any other regulatory interactions) and patents. Prepare presentation materials and clearly communicate research results to manager, and

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "a266d00787929477eafc5483987e0752" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressRegion": "CA", "addressLocality": "South San Francisco" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 175000, "maxValue": 200000, "unitText": "YEAR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-scientist-process-chemistry-a266d007" } }, { "@type": "ListItem", "position": 7, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/medical-director-senior-medical-director-clinical-development-prostate-9c891761", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Medical Director/Senior Medical Director, Clinical Development (Prostate)", "description": "

Medical Director/Senior Medical Director, Clinical Development (Prostate) at ORIC Pharmaceuticals - San Diego, CA, United States - Medical Director/Senior Medical Director, Clinical Development (Prostate) San Diego, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . We are seeking an experienced oncology physician to serve as a Medical Director or Senior Medical Director at ORIC Pharmaceuticals. This role provides medical leadership across one or more clinical development programs, with a primary focus on late-stage (registration-enabling) clinical trials. The position plays a critical role in shaping clinical strategy, ensuring scientific rigor, guiding regulatory interactions, and advancing programs from study design through regulatory submission. The Medical Director will work in close partnership with cross-functional teams including Clinical Operations, Regulatory Affairs, Biostatistics, Safety/Pharmacovigilance, Translational Medicine, and Medical Affairs. The role requires strong strategic thinking, hands-on execution, and the ability to lead effectively in a fast-paced biotech environment. Job Description: Clinical and Medical Leadership Serve as the medical lead

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "9c89176164c85fa5728f5e59332586cc" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressRegion": "CA", "addressLocality": "San Diego" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 270000, "maxValue": 320000, "unitText": "YEAR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "no requirements", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/medical-director-senior-medical-director-clinical-development-prostate-9c891761" } }, { "@type": "ListItem", "position": 8, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/director-medical-affairs-630ba11a", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Director, Medical Affairs", "description": "

Director, Medical Affairs at ORIC Pharmaceuticals - South San Francisco, CA, United States | Remote - Director, Medical Affairs South San Francisco, CA, United States | Remote Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . ORIC Pharmaceuticals is seeking a Director, Medical Affairs, as a member of the Global Medical Affairs (GMA) team based in ORIC's South San Francisco office. Reporting to the Head of Medical Affairs, this individual will be responsible for developing and executing the GMA strategy and tactical plans with a focus on launch readiness and life cycle management for therapies across prostate cancer, non-small cell lung cancer (NSCLC), and potentially other tumor types. The successful candidate will have a proven track record of developing and driving medical strategy for multiple assets with a focus on effectively analyzing and communicating key scientific data through publications, medical information, medical communications, congress activities as well as gathering insights through advisory boards, advocacy, and

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "630ba11aa64c439dff400a8391d91328" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocationType": "TELECOMMUTE", "applicantLocationRequirements": { "@type": "Country", "name": "USA" }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 220000, "maxValue": 275000, "unitText": "YEAR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 96 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/director-medical-affairs-630ba11a" } }, { "@type": "ListItem", "position": 9, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/regulatory-affairs-manager-62c740ca", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Regulatory Affairs Manager", "description": "

Regulatory Affairs Manager at ORIC Pharmaceuticals - San Diego, CA, United States - Regulatory Affairs Manager San Diego, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) ORIC-114, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. Job Description: We are seeking a motivated Regulatory Affairs professional to join our team and help advance the clinical development of oncology products at ORIC. In this role, you will collaborate closely with colleagues across regulatory operations, quality, CMC, nonclinical and clinical functions to support high-quality, timely regulatory submissions. The ideal candidate is a proactive team player who thrives in cross-functional environments, communicates effectively, and can balance strategic thinking with strong execution. Essential duties and responsibilities include the following. Other duties may be assigned. Support regulatory submissions and contribute to strategic planning for assigned programs. Prepare and deliver high-quality and timely regulatory submissions in compliance with applicable regulatory requirements. Responsible for the creation, assembly, review, and archival of complex regulatory submissions which require interaction with internal and CRO teams to ensure optimal execution. Develop, manage and track regulatory submission

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "62c740ca0b2625277c4283ce15f12832" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressRegion": "CA", "addressLocality": "San Diego" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 145000, "maxValue": 165000, "unitText": "YEAR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "Bachelors", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/regulatory-affairs-manager-62c740ca" } }, { "@type": "ListItem", "position": 10, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-scientist-analytical-sciences-52d4ae35", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Senior Scientist, Analytical Sciences", "description": "

Senior Scientist, Analytical Sciences at ORIC Pharmaceuticals - South San Francisco, CA, United States - Senior Scientist, Analytical Sciences South San Francisco, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . We are seeking a lab-based, highly motivated Senior Scientist in Analytical Sciences. The candidate will be part of cross-functional teams providing analytical leadership on projects, work closely on a shared mission to bring new therapeutics to cancer patients. The successful candidate will report to the Sr. Director of Analytical Sciences Job Description: Independently lead analytical development and product characterization activities for our drug development portfolios. Provide oversight, technical guidance and tactical direction for analytical method development, transfer, validation, release, and stability testing activities at CDMOs. Function as a subject matter expert for in-depth physical/ chemical characterization of NCEs at CROs. Independently conceptualize, design, and conduct experiments; interpret and present data and conclusions to various audience, including senior leadership. Expected to

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "CONTRACTOR", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "52d4ae358737e47f8f533ef9aa40e10f" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressRegion": "CA", "addressLocality": "South San Francisco" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 150000, "maxValue": 180000, "unitText": "YEAR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 36 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-scientist-analytical-sciences-52d4ae35" } }, { "@type": "ListItem", "position": 11, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-director-director-cmc-regulatory-affairs-507fd011", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Senior Director/ Director, CMC Regulatory Affairs", "description": "

Senior Director/ Director, CMC Regulatory Affairs at ORIC Pharmaceuticals - South San Francisco, CA, United States - Senior Director/ Director, CMC Regulatory Affairs South San Francisco, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib (ORIC-114), a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . Reporting to the Chief Technical Officer, we are currently hiring a Director, CMC Regulatory Affairs, to join our Technical Operations team. This position is responsible for leading CMC regulatory activities and supporting all of ORIC's clinical development programs for oncology products. The role involves close collaboration with cross-functional teams including regulatory affairs, regulatory operations, quality, CMC, nonclinical, and clinical departments. Job Description: Oversee and direct all CMC regulatory strategies in compliance with global regulatory requirements for the development of ORIC's products. Provide CMC regulatory support for new and ongoing clinical trials, e.g., manage/prepare CMC document packages in support of INDs, CTAs and amendments to global regulatory agencies (RAs) and health authorities (HAs) Work collaboratively with Pharmaceutical Development, Drug Substance, and GMP Quality Assurance, in addition to Project Management, Clinical Operations, Clinical Supply, and Regulatory Operations. Lead

", "datePosted": "2026-06-10T03:52:15.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "ORIC Pharmaceuticals", "value": "507fd011f01b712edcf255e99ba0d0e4" }, "hiringOrganization": { "@type": "Organization", "name": "ORIC Pharmaceuticals" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressRegion": "CA", "addressLocality": "South San Francisco" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 220000, "maxValue": 300000, "unitText": "YEAR" } }, "directApply": false, "incentiveCompensation": "Equity (Rsu, Options, Espp)", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 96 }, "educationRequirements": "Doctorate", "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/senior-director-director-cmc-regulatory-affairs-507fd011" } }, { "@type": "ListItem", "position": 12, "url": "https://fewerjobs.com/jobs/oric-pharmaceuticals/director-clinical-quality-assurance-08183a0e", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Director, Clinical Quality Assurance", "description": "

Director, Clinical Quality Assurance at ORIC Pharmaceuticals - San Diego, CA, United States - Director, Clinical Quality Assurance San Diego, CA, United States Company Description: ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com , and follow us on X or LinkedIn . Reporting to the Senior Vice President of Quality, the Director of Clinical Quality Assurance will lead the Clinical QA function and provide strategic leadership and operational oversight across global early to late-stage clinical programs. The role is responsible for the development, implementation and oversight of quality policies, procedures, and risk-based systems appropriate for advancement of clinical programs. This individual will ensure compliance with global regulatory regulations, as applicable. The successful candidate will work closely with Clinical Development, Clinical Operations, Regulatory Affairs, and third-party Contract organizations to prepare the team for BLA/BIMO milestones. An in-depth understanding of global Health Authority requirements, clinical program management, quality systems, validation, and data integrity are essential requirements of the role. Job Description: Ensure compliance with all

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