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Our programs take novel approaches to shutting down one of cancer's most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer. Reporting to the Chief Medical Officer, the SVP Biometrics will be accountable for biometrics activities for all programs from IND-enabling to registration and launch. This includes leadership of the Biostatistics, Statistical Programming & Analysis, and Clinical Data Management functions. This role requires hands-on execution as well as oversight of internal and external staff. In addition, this person will represent the Biometrics function on the Erasca leadership team and in cross-functional discussions and decision making. The ideal candidate will have excellent technical skills, a track record of developing and mentoring strong teams, significant experience in all phases of oncology drug development, a track record of successful regulatory interactions, and excellent communication skills and executive presence. 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Clinical Trial Manager/Sr Clinical Trial Manager at Erasca Inc - San Diego, CA or remote - Clinical Trial Manager/Sr Clinical Trial Manager San Diego, CA or remote Erasca is a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer's most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer. The Clinical Trial Manager or Senior Clinical Trial Manager assists in the planning, implementation, and management of clinical studies from concept to completion. The position requires knowledge of clinical trial processes and prior experience in many aspects of trial execution from study start-up to study close-out, including assisting in the management of clinical vendors/CROs and assisting in the oversight of resources, budgets, contracts, and timelines. Essential Duties and Responsibilities: - Manage global clinical trials (Phase 1-3) in oncology indications, ensuring that studies are carried out in accordance with the clinical development plan, ICH-GCP, and FDA/other regulatory agency requirements. - Recruit global study sites and foster relationships with study investigators. - Participate in the process of site and vendor selection, qualification, and activation. - Develop Requests-for-Proposals and assist in vendor selection efforts. - Assist in review and negotiation of vendor contracts and study site clinical trial agreements. - Manage study vendors (e.g., CRO, IRT, laboratories, core ECG/imaging).

", "datePosted": "2026-06-11T21:56:22.000Z", "employmentType": "OTHER", "identifier": { "@type": "PropertyValue", "name": "Erasca Inc", "value": "248906e93a61c060c1b558069a9d822e" }, "hiringOrganization": { "@type": "Organization", "name": "Erasca Inc" }, "jobLocationType": "TELECOMMUTE", "applicantLocationRequirements": { "@type": "Country", "name": "USA" }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 145000, "maxValue": 190000, "unitText": "YEAR" } }, "directApply": false, "jobBenefits": "401(k) match", "incentiveCompensation": "Equity (Rsu, Options, Espp); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 60 }, "educationRequirements": "no requirements", "url": "https://fewerjobs.com/jobs/erasca/clinical-trial-manager-sr-clinical-trial-manager-248906e9" } }, { "@type": "ListItem", "position": 2, "url": "https://fewerjobs.com/jobs/erasca/assoc-director-director-pharmaceutical-development-3c00e900", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "Assoc Director/Director, Pharmaceutical Development", "description": "

Assoc Director/Director, Pharmaceutical Development at Erasca Inc - South San Francisco, CA - Assoc Director/Director, Pharmaceutical Development South San Francisco, CA Erasca is a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer's most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer. Position Summary: Reporting to the Sr Director Pharmaceutical Development, the Associate Director or Director of Pharmaceutical Development will be a liaison for the manufacture of Erasca's small molecule development drug products (DPs) at external contract development and manufacturing organizations (CDMOs). This individual will work on cross functional teams with colleagues from process development, analytical, formulation development, supply chain, QA, and regulatory CMC to plan, coordinate, and execute internal and external DP development and manufacturing activities. Essential Duties and Responsibilities: - Provide scientific, technical, and strategic direction to the design, development, and manufacture of investigational drug products from pre-clinical/clinical to commercial stage. - Manage activities and contractual relationship with contract manufacturers and laboratories performing product/formulation development, manufacturing, analytical development and testing, stability, and validation services. - Lead and collaborate with cross functional project team members to meet CMC goals. - Represent CMC DP and provide strategic recommendations and status reporting to cross-functional program team. - Author, review, and/or approve development

", "datePosted": "2026-06-11T02:14:44.000Z", "employmentType": "CONTRACTOR", "identifier": { "@type": "PropertyValue", "name": "Erasca Inc", "value": "3c00e9008e2d6dad1061121597ef75af" }, "hiringOrganization": { "@type": "Organization", "name": "Erasca Inc" }, "jobLocation": { "@type": "Place", "address": { "@type": "PostalAddress", "addressCountry": "US", "addressLocality": "South San Francisco" } }, "baseSalary": { "@type": "MonetaryAmount", "currency": "USD", "value": { "@type": "QuantitativeValue", "minValue": 200000, "maxValue": 225000, "unitText": "YEAR" } }, "directApply": false, "jobBenefits": "401(k) match", "incentiveCompensation": "Equity (Rsu, Options, Espp); Bonus", "experienceRequirements": { "@type": "OccupationalExperienceRequirements", "monthsOfExperience": 120 }, "educationRequirements": "no requirements", "url": "https://fewerjobs.com/jobs/erasca/assoc-director-director-pharmaceutical-development-3c00e900" } }, { "@type": "ListItem", "position": 3, "url": "https://fewerjobs.com/jobs/erasca/svp-late-clinical-development-04c53a03", "item": { "@context": "https://schema.org", "@type": "JobPosting", "title": "SVP Late Clinical Development", "description": "

SVP Late Clinical Development at Erasca Inc - San Diego, CA or remote - SVP Late Clinical Development San Diego, CA or remote Erasca is a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer's most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer. Reporting to the Chief Medical Officer, the SVP Late Clinical Development will provide medical leadership and oversight of late-stage clinical trials and collaborate with the CMO across the Erasca portfolio. In addition, the SVP will be a hands-on drug developer and will serve as clinical lead and/or medical monitor on programs or studies. A key area of focus will be the design and execution of multiple registration enabling trials in solid tumor indications. Essential Duties and Responsibilities: - Provide medical direction and high-quality scientific and clinical knowledge to guide the strategy and execution of late-stage clinical programs and contribute to clinical decision making across the Erasca portfolio. Participate in building and maintaining a culture of rigorous data-driven decision making. - Lead late clinical development function, directly and through reports. - Responsibilities will include clinical development strategy, protocol development, registrational strategy, KOL and academic site interactions, competitive landscape diligence, presentation of data, and other clinical deliverables. - Serve as

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SVP Biometrics at Erasca Inc - San Diego, CA or remote - SVP Biometrics San Diego, CA or remote Erasca is a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer's most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer. Reporting to the Chief Medical Officer, the SVP Biometrics will be accountable for biometrics activities for all programs from IND-enabling to registration and launch. This includes leadership of the Biostatistics, Statistical Programming & Analysis, and Clinical Data Management functions. This role requires hands-on execution as well as oversight of internal and external staff. In addition, this person will represent the Biometrics function on the Erasca leadership team and in cross-functional discussions and decision making. The ideal candidate will have excellent technical skills, a track record of developing and mentoring strong teams, significant experience in all phases of oncology drug development, a track record of successful regulatory interactions, and excellent communication skills and executive presence. Essential D uties and R e sponsibilities : - Build, m aintain , and develop a high performing team across Biostatistics, Statistical Programming & Analysis , and Clinical Data Management. - Ensure systems, capabilities and resources are in place that optimize the design, conduct, analysis and

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